Christine A. Orengo

Publication Activity (10 Years)

Years Active: 1996-2023
Publications (10 Years): 31

Top Topics

Structural Similarities

Genome Sequences

Top Venues

Nucleic Acids Res.

PLoS Comput. Biol.

Publications

Vamsi Nallapareddy, Nicola Bordin, Ian Sillitoe, Michael Heinzinger, Maria Littmann, Vaishali P. Waman, Neeladri Sen, Burkhard Rost, Christine A. Orengo
CATHe: detection of remote homologues for CATH superfamilies using embeddings from protein language models. Bioinform. 39 (1) (2023)
Typhaine Paysan-Lafosse, Matthias Blum, Sara Chuguransky, Tiago Grego, Beatriz Lázaro Pinto, Gustavo A. Salazar, Maxwell L. Bileschi, Peer Bork, Alan Bridge, Lucy J. Colwell, Julian Gough, Daniel H. Haft, Ivica Letunic, Aron Marchler-Bauer, Huaiyu Mi, Darren A. Natale, Christine A. Orengo, Arun Prasad Pandurangan, Catherine Rivoire, Christian J. A. Sigrist, Ian Sillitoe, Narmada Thanki, Paul D. Thomas, Silvio C. E. Tosatto, Cathy H. Wu, Alex Bateman
InterPro in 2022. Nucleic Acids Res. 51 (D1) (2023)
Thibault Tubiana, Ian Sillitoe, Christine A. Orengo, Nathalie Reuter
Dissecting peripheral protein-membrane interfaces. PLoS Comput. Biol. 18 (12) (2022)
Elena Rojano, Fernando Moreno Jabato, James Richard Perkins, José Córdoba-Caballero, Federico García-Criado, Ian Sillitoe, Christine A. Orengo, Juan A. G. Ranea, Pedro Seoane-Zonjic
Assigning protein function from domain-function associations using DomFun. BMC Bioinform. 23 (1) (2022)
Valérie de Crécy-Lagard, Rocio Amorin de Hegedus, Cecilia N. Arighi, Jill Babor, Alex Bateman, Ian Blaby, Crysten Blaby-Haas, Alan Bridge, Stephen K. Burley, Stacey Cleveland, Lucy J. Colwell, Ana Conesa, Christian Dallago, Antoine Danchin, Anita de Waard, Adam Deutschbauer, Raquel Dias, Yousong Ding, Gang Fang, Iddo Friedberg, John Gerlt, Joshua Goldford, Mark Gorelik, Benjamin M. Gyori, Christopher Henry, Geoffrey Hutinet, Marshall Jaroch, Peter D. Karp, Liudmyla Kondratova, Zhiyong Lu, Aron Marchler-Bauer, Maria Jesus Martin, Claire D. McWhite, Gaurav D. Moghe, Paul Monaghan, Anne Morgat, Christopher J. Mungall, Darren A. Natale, William C. Nelson, Seán I. O'Donoghue, Christine A. Orengo, Katherine H. O'Toole, Predrag Radivojac, Colbie Reed, Richard J. Roberts, Dmitri Rodionov, Irina A. Rodionova, Jeffrey DePons, Lana Saleh, Gloria M. Sheynkman, Françoise Thibaud-Nissen, Paul D. Thomas, Peter Uetz, David Vallenet, Erica Watson Carter, Peter Weigele, Valerie Wood, Elisha M. Wood-Charlson, Jin Xu
A roadmap for the functional annotation of protein families: a community perspective. Database J. Biol. Databases Curation 2022 (2022) (2022)
Mihaly Varadi, Stephen Anyango, David R. Armstrong, John M. Berrisford, Preeti Choudhary, Mandar S. Deshpande, Nurul Nadzirin, Sreenath Nair, Lukás Pravda, Ahsan Tanweer, Bissan Al-Lazikani, Claudia Andreini, Geoffrey J. Barton, David Bednar, Karel Berka, Tom L. Blundell, Kelly Brock, José María Carazo, Jirí Damborský, Alessia David, Sucharita Dey, Roland L. Dunbrack Jr., Juan Fernández-Recio, Franca Fraternali, Toby J. Gibson, Manuela Helmer-Citterich, David Hoksza, Thomas A. Hopf, David Jakubec, Natarajan Kannan, Radoslav Krivák, Manjeet Kumar, Emmanuel D. Levy, Nir London, José Ramón Macías, Mallur Srivatsan Madhusudhan, Debora S. Marks, Lennart Martens, Stuart A McGowan, Jake E. McGreig, Vivek Modi, R. Gonzalo Parra, Gerardo Pepe, Damiano Piovesan, Jaime Prilusky, Valeria Putignano, Leandro G. Radusky, Pathmanaban Ramasamy, Atilio O. Rausch, Nathalie Reuter, Luis A. Rodriguez, Nathan J. Rollins, Antonio Rosato, Pawel Rubach, Luis Serrano, Gulzar Singh, Petr Skoda, Carlos Oscar Sánchez Sorzano, Jan Stourac, Joanna I. Sulkowska, Radka Svobodová Vareková, Natalia Tichshenko, Silvio C. E. Tosatto, Wim F. Vranken, Mark N. Wass, Dandan Xue, Daniel Zaidman, Janet M. Thornton, Michael J. E. Sternberg, Christine A. Orengo, Sameer Velankar
PDBe-KB: collaboratively defining the biological context of structural data. Nucleic Acids Res. 50 (D1) (2022)
Neeladri Sen, Ivan Anishchenko, Nicola Bordin, Ian Sillitoe, Sameer Velankar, David Baker, Christine A. Orengo
Characterizing and explaining the impact of disease-associated mutations in proteins without known structures or structural homologs. Briefings Bioinform. 23 (4) (2022)
M. Michael Gromiha, Christine A. Orengo, Ramanathan Sowdhamini, Janet M. Thornton
Srinivasan (1962-2021) in Bioinformatics and beyond. Bioinform. 38 (8) (2022)
Ian Sillitoe, Nicola Bordin, Natalie L. Dawson, Vaishali P. Waman, Paul Ashford, Harry M. Scholes, Camilla S. M. Pang, Laurel Woodridge, Clemens Rauer, Neeladri Sen, Mahnaz Abbasian, Sean Le Cornu, Su Datt Lam, Karel Berka, Ivana Hutarová Vareková, Radka Svobodová Vareková, Jonathan G. Lees, Christine A. Orengo
CATH: increased structural coverage of functional space. Nucleic Acids Res. 49 (Database-Issue) (2021)
Sayoni Das, Harry M. Scholes, Neeladri Sen, Christine A. Orengo
CATH functional families predict functional sites in proteins. Bioinform. 37 (8) (2021)
Su Datt Lam, M. Madan Babu, Jonathan G. Lees, Christine A. Orengo
Biological impact of mutually exclusive exon switching. PLoS Comput. Biol. 17 (3) (2021)
Maria Littmann, Nicola Bordin, Michael Heinzinger, Konstantin Schütze, Christian Dallago, Christine A. Orengo, Burkhard Rost
Clustering FunFams using sequence embeddings improves EC purity. Bioinform. 37 (20) (2021)
Matthias Blum, Hsin-Yu Chang, Sara Chuguransky, Tiago Grego, Swaathi Kandasamy, Alex L. Mitchell, Gift Nuka, Typhaine Paysan-Lafosse, Matloob Qureshi, Shriya Raj, Lorna J. Richardson, Gustavo A. Salazar, Lowri Williams, Peer Bork, Alan Bridge, Julian Gough, Daniel H. Haft, Ivica Letunic, Aron Marchler-Bauer, Huaiyu Mi, Darren A. Natale, Marco Necci, Christine A. Orengo, Arun Prasad Pandurangan, Catherine Rivoire, Christian J. A. Sigrist, Ian Sillitoe, Narmada Thanki, Paul D. Thomas, Silvio C. E. Tosatto, Cathy H. Wu, Alex Bateman, Robert D. Finn
The InterPro protein families and domains database: 20 years on. Nucleic Acids Res. 49 (Database-Issue) (2021)
Vaishali P. Waman, Neeladri Sen, Mihaly Varadi, Antoine Daina, Shoshana J. Wodak, Vincent Zoete, Sameer Velankar, Christine A. Orengo
The impact of structural bioinformatics tools and resources on SARS-CoV-2 research and therapeutic strategies. Briefings Bioinform. 22 (2) (2021)
Ian Sillitoe, Antonina Andreeva, Tom L. Blundell, Daniel W. A. Buchan, Robert D. Finn, Julian Gough, David T. Jones, Lawrence A. Kelley, Typhaine Paysan-Lafosse, Su Datt Lam, Alexey G. Murzin, Arun Prasad Pandurangan, Gustavo A. Salazar, Marcin J. Skwark, Michael J. E. Sternberg, Sameer Velankar, Christine A. Orengo
Genome3D: integrating a collaborative data pipeline to expand the depth and breadth of consensus protein structure annotation. Nucleic Acids Res. 48 (Database-Issue) (2020)
Rachel Drysdale, Charles E. Cook, Robert Petryszak, Vivienne Baillie Gerritsen, Mary Barlow, Elisabeth Gasteiger, Franziska Gruhl, Jürgen Haas, Jerry Lanfear, Rodrigo Lopez, Nicole Redaschi, Heinz Stockinger, Daniel Teixeira, Aravind Venkatesan, Alex Bateman, Alan Bridge, Guy Cochrane, Robert D. Finn, Frank Oliver Glöckner, Marc Hanauer, Thomas M. Keane, Andrew Leach, Luana Licata, Per Oksvold, Sandra E. Orchard, Christine A. Orengo, Helen E. Parkinson, Bengt Persson, Pablo Porras, Jordi Rambla, Ana Rath, Charlotte Rodwell, Ugis Sarkans, Dietmar Schomburg, Ian Sillitoe, J. Dylan Spalding, Mathias Uhlén, Sameer Velankar, Juan Antonio Vizcaíno, Kalle von Feilitzen, Christian von Mering, Andrew D. Yates, Niklas Blomberg, Christine Durinx, Johanna R. McEntyre
The ELIXIR Core Data Resources: fundamental infrastructure for the life sciences. Bioinform. 36 (8) (2020)
Mihaly Varadi, John M. Berrisford, Mandar S. Deshpande, Sreenath Nair, Aleksandras Gutmanas, David R. Armstrong, Lukás Pravda, Bissan Al-Lazikani, Stephen Anyango, Geoffrey J. Barton, Karel Berka, Tom L. Blundell, Neera Borkakoti, Jose M. Dana, Sayoni Das, Sucharita Dey, Patrizio Di Micco, Franca Fraternali, Toby J. Gibson, Manuela Helmer-Citterich, David Hoksza, Liang-Chin Huang, Rishabh Jain, Harry Jubb, Christos C. Kannas, Natarajan Kannan, Jaroslav Koca, Radoslav Krivák, Manjeet Kumar, Emmanuel D. Levy, Fábio Madeira, M. S. Madhusudhan, Henry J. Martell, Stuart A. MacGowan, Jake E. McGreig, Saqib Mir, Abhik Mukhopadhyay, Luca Parca, Typhaine Paysan-Lafosse, Leandro G. Radusky, António J. M. Ribeiro, Luis Serrano, Ian Sillitoe, Gulzar Singh, Petr Skoda, Radka Svobodová Vareková, Jonathan D. Tyzack, Alfonso Valencia, Eloy D. Villasclaras-Fernández, Wim F. Vranken, Mark N. Wass, Janet M. Thornton, Michael J. E. Sternberg, Christine A. Orengo, Sameer Velankar
PDBe-KB: a community-driven resource for structural and functional annotations. Nucleic Acids Res. 48 (Database-Issue) (2020)
Alex L. Mitchell, Teresa K. Attwood, Patricia C. Babbitt, Matthias Blum, Peer Bork, Alan Bridge, Shoshana D. Brown, Hsin-Yu Chang, Sara El-Gebali, Matthew Fraser, Julian Gough, David Haft, Hongzhan Huang, Ivica Letunic, Rodrigo Lopez, Aurelien Luciani, Fábio Madeira, Aron Marchler-Bauer, Huaiyu Mi, Darren A. Natale, Marco Necci, Gift Nuka, Christine A. Orengo, Arun Prasad Pandurangan, Typhaine Paysan-Lafosse, Sebastien Pesseat, Simon C. Potter, Matloob Qureshi, Neil D. Rawlings, Nicole Redaschi, Lorna J. Richardson, Catherine Rivoire, Gustavo A. Salazar, Amaia Sangrador-Vegas, Christian J. A. Sigrist, Ian Sillitoe, Granger G. Sutton, Narmada Thanki, Paul D. Thomas, Silvio C. E. Tosatto, Siew-Yit Yong, Robert D. Finn
InterPro in 2019: improving coverage, classification and access to protein sequence annotations. Nucleic Acids Res. 47 (Database-Issue) (2019)
Linus Scheibenreif, Maria Littmann, Christine A. Orengo, Burkhard Rost
FunFam protein families improve residue level molecular function prediction. BMC Bioinform. 20 (1) (2019)
Ian Sillitoe, Natalie L. Dawson, Tony E. Lewis, Sayoni Das, Jonathan G. Lees, Paul Ashford, Adeyelu Tolulope, Harry M. Scholes, Ilya Senatorov, Andra Bujan, Fatima Ceballos Rodriguez-Conde, Benjamin Dowling, Janet M. Thornton, Christine A. Orengo
CATH: expanding the horizons of structure-based functional annotations for genome sequences. Nucleic Acids Res. 47 (Database-Issue) (2019)
Elena Rojano, James Richard Perkins, Ian Sillitoe, Christine A. Orengo, Juan Antonio Garcia-Ranea, Pedro Seoane
Associating Protein Domains with Biological Functions: A Tripartite Network Approach. IWBBIO (2) (2019)
Tony E. Lewis, Ian Sillitoe, Natalie L. Dawson, Su Datt Lam, Tristan Clarke, David A. Lee, Christine A. Orengo, Jonathan G. Lees
Gene3D: Extensive prediction of globular domains in proteins. Nucleic Acids Res. 46 (Database-Issue) (2018)
Tony E. Lewis, Ian Sillitoe, Natalie L. Dawson, Su Datt Lam, Tristan Clarke, David A. Lee, Christine A. Orengo, Jonathan G. Lees
Gene3D: Extensive prediction of globular domains in proteins. Nucleic Acids Res. 46 (Database-Issue) (2018)
Cen Wan, Jonathan G. Lees, Federico Minneci, Christine A. Orengo, David T. Jones
Analysis of temporal transcription expression profiles reveal links between protein function and developmental stages of Drosophila melanogaster. PLoS Comput. Biol. 13 (10) (2017)
Natalie L. Dawson, Tony E. Lewis, Sayoni Das, Jonathan G. Lees, David A. Lee, Paul Ashford, Christine A. Orengo, Ian Sillitoe
CATH: an expanded resource to predict protein function through structure and sequence. Nucleic Acids Res. 45 (Database-Issue) (2017)
Bonnie Berger, Terry Gaasterland, Thomas Lengauer, Christine A. Orengo, Bruno Gaëta, Scott Markel, Alfonso Valencia
ISCB's initial reaction to New England Journal of Medicine editorial on data sharing. Bioinform. 33 (18) (2017)
Robert D. Finn, Teresa K. Attwood, Patricia C. Babbitt, Alex Bateman, Peer Bork, Alan Bridge, Hsin-Yu Chang, Zsuzsanna Dosztányi, Sara El-Gebali, Matthew Fraser, Julian Gough, David Haft, Gemma L. Holliday, Hongzhan Huang, Xiaosong Huang, Ivica Letunic, Rodrigo Lopez, Shennan Lu, Aron Marchler-Bauer, Huaiyu Mi, Jaina Mistry, Darren A. Natale, Marco Necci, Gift Nuka, Christine A. Orengo, Youngmi Park, Sebastien Pesseat, Damiano Piovesan, Simon C. Potter, Neil D. Rawlings, Nicole Redaschi, Lorna J. Richardson, Catherine Rivoire, Amaia Sangrador-Vegas, Christian J. A. Sigrist, Ian Sillitoe, Ben Smithers, Silvano Squizzato, Granger G. Sutton, Narmada Thanki, Paul D. Thomas, Silvio C. E. Tosatto, Cathy H. Wu, Ioannis Xenarios, Lai-Su L. Yeh, Siew-Yit Yong, Alex L. Mitchell
InterPro in 2017 - beyond protein family and domain annotations. Nucleic Acids Res. 45 (Database-Issue) (2017)
Su Datt Lam, Natalie L. Dawson, Sayoni Das, Ian Sillitoe, Paul Ashford, David A. Lee, Sonja Lehtinen, Christine A. Orengo, Jonathan G. Lees
Gene3D: expanding the utility of domain assignments. Nucleic Acids Res. 44 (Database-Issue) (2016)
David A. Lee, Sayoni Das, Natalie L. Dawson, Dragana Dobrijevic, John Ward, Christine A. Orengo
Novel Computational Protocols for Functionally Classifying and Characterising Serine Beta-Lactamases. PLoS Comput. Biol. 12 (6) (2016)
Sayoni Das, David A. Lee, Ian Sillitoe, Natalie L. Dawson, Jonathan G. Lees, Christine A. Orengo
Functional classification of CATH superfamilies: a domain-based approach for protein function annotation. Bioinform. 32 (18) (2016)
Bonnie Berger, Terry Gaasterland, Thomas Lengauer, Christine A. Orengo, Bruno Gaëta, Scott Markel, Alfonso Valencia
Editorial on Data Sharing. PLoS Comput. Biol. 12 (3) (2016)
Tony E. Lewis, Ian Sillitoe, Antonina Andreeva, Tom L. Blundell, Daniel W. A. Buchan, Cyrus Chothia, Domenico Cozzetto, Jose M. Dana, Ioannis Filippis, Julian Gough, David T. Jones, Lawrence A. Kelley, Gerard J. Kleywegt, Federico Minneci, Jaina Mistry, Alexey G. Murzin, Bernardo Ochoa-Montaño, Matt E. Oates, Marco Punta, Owen J. L. Rackham, Jonathan Stahlhacke, Michael J. E. Sternberg, Sameer Velankar, Christine A. Orengo
Genome3D: exploiting structure to help users understand their sequences. Nucleic Acids Res. 43 (Database-Issue) (2015)
Sayoni Das, Ian Sillitoe, David A. Lee, Jonathan G. Lees, Natalie L. Dawson, John Ward, Christine A. Orengo
CATH FunFHMMer web server: protein functional annotations using functional family assignments. Nucleic Acids Res. 43 (Webserver-Issue) (2015)
Ian Sillitoe, Tony E. Lewis, Alison L. Cuff, Sayoni Das, Paul Ashford, Natalie L. Dawson, Nicholas Furnham, Roman A. Laskowski, David A. Lee, Jonathan G. Lees, Sonja Lehtinen, Romain A. Studer, Janet M. Thornton, Christine A. Orengo
CATH: comprehensive structural and functional annotations for genome sequences. Nucleic Acids Res. 43 (Database-Issue) (2015)
Alex L. Mitchell, Hsin-Yu Chang, Louise C. Daugherty, Matthew Fraser, Sarah Hunter, Rodrigo Lopez, Craig McAnulla, Conor McMenamin, Gift Nuka, Sebastien Pesseat, Amaia Sangrador-Vegas, Maxim Scheremetjew, Claudia Rato, Siew-Yit Yong, Alex Bateman, Marco Punta, Teresa K. Attwood, Christian J. A. Sigrist, Nicole Redaschi, Catherine Rivoire, Ioannis Xenarios, Daniel Kahn, Dominique Guyot, Peer Bork, Ivica Letunic, Julian Gough, Matt E. Oates, Daniel H. Haft, Hongzhan Huang, Darren A. Natale, Cathy H. Wu, Christine A. Orengo, Ian Sillitoe, Huaiyu Mi, Paul D. Thomas, Robert D. Finn
The InterPro protein families database: the classification resource after 15 years. Nucleic Acids Res. 43 (Database-Issue) (2015)
Sayoni Das, David A. Lee, Ian Sillitoe, Natalie L. Dawson, Jonathan G. Lees, Christine A. Orengo
Functional classification of CATH superfamilies: a domain-based approach for protein function annotation. Bioinform. 31 (21) (2015)
Jonathan G. Lees, Jean-Karim Hériché, Ian Morilla, José María Fernández, Priit Adler, Martin Krallinger, Jaak Vilo, Alfonso Valencia, Jan Ellenberg, Juan A. G. Ranea, Christine A. Orengo
FUN-L: gene prioritization for RNAi screens. Bioinform. 31 (12) (2015)
Jonathan G. Lees, David A. Lee, Romain A. Studer, Natalie L. Dawson, Ian Sillitoe, Sayoni Das, Corin Yeats, Benoit H. Dessailly, Robert Rentzsch, Christine A. Orengo
Gene3D: Multi-domain annotations for protein sequence and comparative genome analysis. Nucleic Acids Res. 42 (Database-Issue) (2014)
Tony E. Lewis, Ian Sillitoe, Antonina Andreeva, Tom L. Blundell, Daniel W. A. Buchan, Cyrus Chothia, Alison L. Cuff, Jose M. Dana, Ioannis Filippis, Julian Gough, Sarah Hunter, David T. Jones, Lawrence A. Kelley, Gerard J. Kleywegt, Federico Minneci, Alex L. Mitchell, Alexey G. Murzin, Bernardo Ochoa-Montaño, Owen J. L. Rackham, James Smith, Michael J. E. Sternberg, Sameer Velankar, Corin Yeats, Christine A. Orengo
Genome3D: a UK collaborative project to annotate genomic sequences with predicted 3D structures based on SCOP and CATH domains. Nucleic Acids Res. 41 (Database-Issue) (2013)
Ian Sillitoe, Alison L. Cuff, Benoit H. Dessailly, Natalie L. Dawson, Nicholas Furnham, David A. Lee, Jonathan G. Lees, Tony E. Lewis, Romain A. Studer, Robert Rentzsch, Corin Yeats, Janet M. Thornton, Christine A. Orengo
New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures. Nucleic Acids Res. 41 (Database-Issue) (2013)
Robert Rentzsch, Christine A. Orengo
Protein function prediction using domain families. BMC Bioinform. 14 (S-3) (2013)
Jonathan G. Lees, Corin Yeats, James Richard Perkins, Ian Sillitoe, Robert Rentzsch, Benoit H. Dessailly, Christine A. Orengo
Gene3D: a domain-based resource for comparative genomics, functional annotation and protein network analysis. Nucleic Acids Res. 40 (Database-Issue) (2012)
Sarah Hunter, Philip Jones, Alex L. Mitchell, Rolf Apweiler, Teresa K. Attwood, Alex Bateman, Thomas Bernard, David Binns, Peer Bork, Sarah W. Burge, Edouard De Castro, Penny C. Coggill, Matthew Corbett, Ujjwal Das, Louise C. Daugherty, Lauranne Duquenne, Robert D. Finn, Matthew Fraser, Julian Gough, Daniel H. Haft, Nicolas Hulo, Daniel Kahn, Elizabeth Kelly, Ivica Letunic, David Lonsdale, Rodrigo Lopez, Martin Madera, John Maslen, Craig McAnulla, Jennifer McDowall, Conor McMenamin, Huaiyu Mi, Prudence Mutowo-Meullenet, Nicola J. Mulder, Darren A. Natale, Christine A. Orengo, Sebastien Pesseat, Marco Punta, Antony F. Quinn, Catherine Rivoire, Amaia Sangrador-Vegas, Jeremy D. Selengut, Christian J. A. Sigrist, Maxim Scheremetjew, John G. Tate, Manjulapramila Thimmajanarthanan, Paul D. Thomas, Cathy H. Wu, Corin Yeats, Siew-Yit Yong
InterPro in 2011: new developments in the family and domain prediction database. Nucleic Acids Res. 40 (Database-Issue) (2012)
Nicholas Furnham, Ian Sillitoe, Gemma L. Holliday, Alison L. Cuff, Roman A. Laskowski, Christine A. Orengo, Janet M. Thornton
Exploring the Evolution of Novel Enzyme Functions within Structurally Defined Protein Superfamilies. PLoS Comput. Biol. 8 (3) (2012)
Nicholas Furnham, Ian Sillitoe, Gemma L. Holliday, Alison L. Cuff, Syed Asad Rahman, Roman A. Laskowski, Christine A. Orengo, Janet M. Thornton
FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies. Nucleic Acids Res. 40 (Database-Issue) (2012)
Corin Yeats, Jonathan G. Lees, Phil Carter, Ian Sillitoe, Christine A. Orengo
The Gene3D Web Services: a platform for identifying, annotating and comparing structural domains in protein sequences. Nucleic Acids Res. 39 (Web-Server-Issue) (2011)
Alison L. Cuff, Ian Sillitoe, Tony E. Lewis, Andrew B. Clegg, Robert Rentzsch, Nicholas Furnham, Marialuisa Pellegrini-Calace, David T. Jones, Janet M. Thornton, Christine A. Orengo
Extending CATH: increasing coverage of the protein structure universe and linking structure with function. Nucleic Acids Res. 39 (Database-Issue) (2011)
José M. G. Izarzugaza, Lisa E. M. Hopcroft, Anja Baresic, Christine A. Orengo, Andrew C. R. Martin, Alfonso Valencia
Characterization of pathogenic germline mutations in human Protein Kinases. BMC Bioinform. 12 (S-4) (2011)
Corin Yeats, Oliver Redfern, Christine A. Orengo
A fast and automated solution for accurately resolving protein domain architectures. Bioinform. 26 (6) (2010)
Jonathan G. Lees, Corin Yeats, Oliver Redfern, Andrew B. Clegg, Christine A. Orengo
Gene3D: merging structure and function for a Thousand genomes. Nucleic Acids Res. 38 (Database-Issue) (2010)
Juan A. G. Ranea, Ian Morilla, Jonathan G. Lees, Adam James Reid, Corin Yeats, Andrew B. Clegg, Francisca Sánchez-Jiménez, Christine A. Orengo
Finding the "Dark Matter" in Human and Yeast Protein Network Prediction and Modelling. PLoS Comput. Biol. 6 (9) (2010)
José M. G. Izarzugaza, Anja Baresic, Lisa E. M. McMillan, Corin Yeats, Andrew B. Clegg, Christine A. Orengo, Andrew C. R. Martin, Alfonso Valencia
An integrated approach to the interpretation of Single Amino Acid Polymorphisms within the framework of CATH and Gene3D. BMC Bioinform. 10 (S-8) (2009)
Oliver Redfern, Benoit H. Dessailly, Timothy Dallman, Ian Sillitoe, Christine A. Orengo
FLORA: A Novel Method to Predict Protein Function from Structure in Diverse Superfamilies. PLoS Comput. Biol. 5 (8) (2009)
Sarah Hunter, Rolf Apweiler, Teresa K. Attwood, Amos Bairoch, Alex Bateman, David Binns, Peer Bork, Ujjwal Das, Louise C. Daugherty, Lauranne Duquenne, Robert D. Finn, Julian Gough, Daniel H. Haft, Nicolas Hulo, Daniel Kahn, Elizabeth Kelly, Aurélie Laugraud, Ivica Letunic, David Lonsdale, Rodrigo Lopez, Martin Madera, John Maslen, Craig McAnulla, Jennifer McDowall, Jaina Mistry, Alex L. Mitchell, Nicola J. Mulder, Darren A. Natale, Christine A. Orengo, Antony F. Quinn, Jeremy D. Selengut, Christian J. A. Sigrist, Manjula Thimma, Paul D. Thomas, Franck Valentin, Derek Wilson, Cathy H. Wu, Corin Yeats
InterPro: the integrative protein signature database. Nucleic Acids Res. 37 (Database-Issue) (2009)
Alison L. Cuff, Ian Sillitoe, Tony E. Lewis, Oliver Redfern, Richard Garratt, Janet M. Thornton, Christine A. Orengo
The CATH classification revisited - architectures reviewed and new ways to characterize structural divergence in superfamilies. Nucleic Acids Res. 37 (Database-Issue) (2009)
Jennifer A. Siepen, Khalid Belhajjame, Julian N. Selley, Suzanne M. Embury, Norman W. Paton, Carole A. Goble, Stephen G. Oliver, Robert Stevens, Lucas Zamboulis, Nigel J. Martin, Alexandra Poulovassilis, Philip Jones, Richard G. Côté, Henning Hermjakob, Melissa M. Pentony, David T. Jones, Christine A. Orengo, Simon J. Hubbard
ISPIDER Central: an integrated database web-server for proteomics. Nucleic Acids Res. 36 (Web-Server-Issue) (2008)
Benoit H. Dessailly, Marc F. Lensink, Christine A. Orengo, Shoshana J. Wodak
-structures. Nucleic Acids Res. 36 (Database-Issue) (2008)
Anna E. Lobley, Timothy Nugent, Christine A. Orengo, David T. Jones
FFPred: an integrated feature-based function prediction server for vertebrate proteomes. Nucleic Acids Res. 36 (Web-Server-Issue) (2008)
Corin Yeats, Jonathan G. Lees, Adam James Reid, Paul Kellam, Nigel J. Martin, Xinhui Liu, Christine A. Orengo
Gene3D: comprehensive structural and functional annotation of genomes. Nucleic Acids Res. 36 (Database-Issue) (2008)
Nicola J. Mulder, Rolf Apweiler, Teresa K. Attwood, Amos Bairoch, Alex Bateman, David Binns, Peer Bork, Virginie Buillard, Lorenzo Cerutti, Richard R. Copley, Emmanuel Courcelle, Ujjwal Das, Louise C. Daugherty, Mark Dibley, Robert D. Finn, Wolfgang Fleischmann, Julian Gough, Daniel H. Haft, Nicolas Hulo, Sarah Hunter, Daniel Kahn, Alexander Kanapin, Anish Kejariwal, Alberto Labarga, Petra S. Langendijk-Genevaux, David Lonsdale, Rodrigo Lopez, Ivica Letunic, Martin Madera, John Maslen, Craig McAnulla, Jennifer McDowall, Jaina Mistry, Alex L. Mitchell, Anastasia N. Nikolskaya, Sandra E. Orchard, Christine A. Orengo, Robert Petryszak, Jeremy D. Selengut, Christian J. A. Sigrist, Paul D. Thomas, Franck Valentin, Derek Wilson, Cathy H. Wu, Corin Yeats
New developments in the InterPro database. Nucleic Acids Res. 35 (Database-Issue) (2007)
Adam James Reid, Corin Yeats, Christine A. Orengo
Methods of remote homology detection can be combined to increase coverage by 10% in the midnight zone. Bioinform. 23 (18) (2007)
Andrew P. Harrison, Caroline E. Johnston, Christine A. Orengo
Establishing a major cause of discrepancy in the calibration of Affymetrix GeneChips. BMC Bioinform. 8 (2007)
Juan A. G. Ranea, Corin Yeats, Alastair Grant, Christine A. Orengo
Predicting Protein Function with Hierarchical Phylogenetic Profiles: The Gene3D Phylo-Tuner Method Applied to Eukaryotic Genomes. PLoS Comput. Biol. 3 (11) (2007)
Lesley H. Greene, Tony E. Lewis, Sarah Addou, Alison L. Cuff, Timothy Dallman, Mark Dibley, Oliver Redfern, Frances M. G. Pearl, Rekha Nambudiry, Adam James Reid, Ian Sillitoe, Corin Yeats, Janet M. Thornton, Christine A. Orengo
The CATH domain structure database: new protocols and classification levels give a more comprehensive resource for exploring evolution. Nucleic Acids Res. 35 (Database-Issue) (2007)
Oliver Redfern, Andrew P. Harrison, Timothy Dallman, Frances M. G. Pearl, Christine A. Orengo
CATHEDRAL: A Fast and Effective Algorithm to Predict Folds and Domain Boundaries from Multidomain Protein Structures. PLoS Comput. Biol. 3 (11) (2007)
Anna E. Lobley, Mark B. Swindells, Christine A. Orengo, David T. Jones
Inferring Function Using Patterns of Native Disorder in Proteins. PLoS Comput. Biol. 3 (8) (2007)
Russell L. Marsden, Tony A. Lewis, Christine A. Orengo
Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint. BMC Bioinform. 8 (2007)
Corin Yeats, Michael Maibaum, Russell L. Marsden, Mark Dibley, David A. Lee, Sarah Addou, Christine A. Orengo
Gene3D: modelling protein structure, function and evolution. Nucleic Acids Res. 34 (Database-Issue) (2006)
Michael Hirsch, Allan Tucker, Stephen Swift, Nigel J. Martin, Christine A. Orengo, Paul Kellam, Xiaohui Liu
Improved Robustness in Time Series Analysis of Gene Expression Data by Polynomial Model Based Clustering. CompLife (2006)
Frances M. G. Pearl, Annabel E. Todd, Ian Sillitoe, Mark Dibley, Oliver Redfern, Tony E. Lewis, Christopher Bennett, Russell L. Marsden, Alastair Grant, David A. Lee, Adrian Akpor, Michael Maibaum, Andrew P. Harrison, Timothy Dallman, Gabrielle A. Reeves, Ilhem Diboun, Sarah Addou, Stefano Lise, Caroline E. Johnston, Antonio Sillero, Janet M. Thornton, Christine A. Orengo
The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis. Nucleic Acids Res. 33 (Database-Issue) (2005)
Michael Maibaum, Lucas Zamboulis, Galia Rimon, Christine A. Orengo, Nigel J. Martin, Alexandra Poulovassilis
Cluster Based Integration of Heterogeneous Biological Databases Using the AutoMed Toolkit. DILS (2005)
Paul Kellam, Stephen Swift, Allan Tucker, Veronica Vinciotti, Nigel J. Martin, Christine A. Orengo, Xiaohui Liu
Consensus Clustering and Functional Interpretation of Gene Expression Data. Spanish Bioinformatics Conference (2004)
Juan Garcia Ranea, Alastair Grant, Janet M. Thornton, Christine A. Orengo
Microeconomic Principles Explain an Optimal Genome Size in Bacteria. Spanish Bioinformatics Conference (2004)
James E. Bray, Russell L. Marsden, Stuart C. G. Rison, Alexei Savchenko, Aled M. Edwards, Janet M. Thornton, Christine A. Orengo
A practical and robust sequence search strategy for structural genomics target selection. Bioinform. 20 (14) (2004)
Michael Maibaum, Galia Rimon, Christine A. Orengo, Nigel J. Martin, Alexandra Poulovassilis
BioMap: Gene Family based Integration of Heterogeneous Biological Databases Using AutoMed Metadata. DEXA Workshops (2004)
David A. Lee, Sandrine Fefeu, Adrian A. Edo-Ukeh, Christine A. Orengo, Christine Slingsby
EyeSite: a semi-automated database of protein families in the eye. Nucleic Acids Res. 32 (Database-Issue) (2004)
David A. Lee, Alastair Grant, Ian Sillitoe, Mark Dibley, Juan Garcia Ranea, Christine A. Orengo
A structural perspective on genome evolution. RECOMB (2004)
Frances M. G. Pearl, C. F. Bennett, James E. Bray, Andrew P. Harrison, Nigel J. Martin, Adrian J. Shepherd, Ian Sillitoe, Janet M. Thornton, Christine A. Orengo
The CATH database: an extended protein family resource for structural and functional genomics. Nucleic Acids Res. 31 (1) (2003)
Christine A. Orengo
A Structural Perspective on Genome Evolution(Invited Talk). German Conference on Bioinformatics (2003)
Andrew P. Harrison, Frances M. G. Pearl, Ian Sillitoe, Tim Slidel, Richard Mott, Janet M. Thornton, Christine A. Orengo
Recognizing the fold of a protein structure. Bioinform. 19 (14) (2003)
Daniel W. A. Buchan, Stuart C. G. Rison, James E. Bray, David A. Lee, Frances M. G. Pearl, Janet M. Thornton, Christine A. Orengo
Gene3D: structural assignments for the biologist and bioinformaticist alike. Nucleic Acids Res. 31 (1) (2003)
Paul Kellam, Xiaohui Liu, Nigel J. Martin, Christine A. Orengo, Stephen Swift, Allan Tucker
A framework for modelling virus gene expression data. Intell. Data Anal. 6 (3) (2002)
Adrian J. Shepherd, Nigel J. Martin, Roger G. Johnson, Paul Kellam, Christine A. Orengo
PFDB: a generic protein family database integrating the CATH domain structure database with sequence based protein family resources. Bioinform. 18 (12) (2002)
Frances M. G. Pearl, Nigel J. Martin, James E. Bray, Daniel W. A. Buchan, Andrew P. Harrison, David A. Lee, Gabrielle A. Reeves, Adrian J. Shepherd, Ian Sillitoe, Annabel E. Todd, Janet M. Thornton, Christine A. Orengo
A rapid classification protocol for the CATH Domain Database to support structural genomics. Nucleic Acids Res. 29 (1) (2001)
Paul Kellam, Xiaohui Liu, Nigel J. Martin, Christine A. Orengo, Stephen Swift, Allan Tucker
A Framework for Modelling Short, High-Dimensional Multivariate Time Series: Preliminary Results in Virus Gene Expression Data Analysis. IDA (2001)
M. Mar Albà, David A. Lee, Frances M. G. Pearl, Adrian J. Shepherd, Nigel J. Martin, Christine A. Orengo, Paul Kellam
VIDA: a virus database system for the organization of animal virus genome open reading frames. Nucleic Acids Res. 29 (1) (2001)
Frances M. G. Pearl, David A. Lee, James E. Bray, Ian Sillitoe, Annabel E. Todd, Andrew P. Harrison, Janet M. Thornton, Christine A. Orengo
Assigning genomic sequences to CATH. Nucleic Acids Res. 28 (1) (2000)
Christine A. Orengo, Frances M. G. Pearl, James E. Bray, Annabel E. Todd, A. C. Martin, Loredana Lo Conte, Janet M. Thornton
The CATH Database provides insights into protein structure/function relationships. Nucleic Acids Res. 27 (1) (1999)
Janet M. Thornton, Andrew C. R. Martin, Christine A. Orengo, Duncan Milburn, Roman A. Laskowski
[Invited Lecture] Protein Folds and Functions. German Conference on Bioinformatics (1998)
Nigel P. Brown, Christine A. Orengo, William R. Taylor
A Protein Structure Comparison Methodology. Comput. Chem. 20 (3) (1996)