Thomas Lengauer

ORCID

Publication Activity (10 Years)

Years Active: 1979-2023
Publications (10 Years): 12

Top Venues

Publications

Giulia Di Teodoro, Martin Pirkl, Francesca Incardona, Ilaria Vicenti, Anders Sönnerborg, Rolf Kaiser, Laura Palagi, Maurizio Zazzi, Thomas Lengauer
Incorporating temporal dynamics of mutations to enhance the prediction capability of antiretroviral therapy's outcome for HIV-1. CoRR (2023)
Matthias Döring, Joachim Büch, Georg Friedrich, Alejandro Pironti, Prabhav Kalaghatgi, Elena Knops, Eva Heger, Martin Obermeier, Martin Däumer, Alexander Thielen, Rolf Kaiser, Thomas Lengauer, Nico Pfeifer
geno2pheno[ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data. Nucleic Acids Res. 46 (Webserver-Issue) (2018)
Bonnie Berger, Terry Gaasterland, Thomas Lengauer, Christine A. Orengo, Bruno Gaëta, Scott Markel, Alfonso Valencia
ISCB's initial reaction to New England Journal of Medicine editorial on data sharing. Bioinform. 33 (18) (2017)
Prabhav Kalaghatgi, Thomas Lengauer
Computing phylogenetic trees using topologically related minimum spanning trees. J. Graph Algorithms Appl. 21 (6) (2017)
Felipe Albrecht, Markus List, Christoph Bock, Thomas Lengauer
DeepBlueR: large-scale epigenomic analysis in R. Bioinform. 33 (13) (2017)
Prabhav Kalaghatgi, Thomas Lengauer
Selecting optimal minimum spanning trees that share a topological correspondence with phylogenetic trees. CoRR (2017)
Felipe Albrecht, Markus List, Christoph Bock, Thomas Lengauer
DeepBlue epigenomic data server: programmatic data retrieval and analysis of epigenome region sets. Nucleic Acids Res. 44 (Webserver-Issue) (2016)
Bonnie Berger, Terry Gaasterland, Thomas Lengauer, Christine A. Orengo, Bruno Gaëta, Scott Markel, Alfonso Valencia
Editorial on Data Sharing. PLoS Comput. Biol. 12 (3) (2016)
Peter D. Karp, Bonnie Berger, Diane E. Kovats, Thomas Lengauer, Michal Linial, Pardis Sabeti, Winston Hide, Burkhard Rost
Message from the ISCB: ISCB Ebola award for important future research on the computational biology of Ebola virus. Bioinform. 31 (4) (2015)
Peter D. Karp, Bonnie Berger, Diane E. Kovats, Thomas Lengauer, Michal Linial, Pardis Sabeti, Winston Hide, Burkhard Rost
ISCB Ebola Award for Important Future Research on the Computational Biology of Ebola Virus. PLoS Comput. Biol. 11 (1) (2015)
Thomas Lengauer, Ruth Nussinov
How to Write a Presubmission Inquiry. PLoS Comput. Biol. 11 (2) (2015)
Peter Ebert, Fabian Müller, Karl Nordström, Thomas Lengauer, Marcel H. Schulz
A general concept for consistent documentation of computational analyses. Database J. Biol. Databases Curation 2015 (2015)
Anna Katharina Hildebrandt, Matthias Dietzen, Thomas Lengauer, Hans-Peter Lenhof, Ernst Althaus, Andreas Hildebrandt
Efficient computation of root mean square deviations under rigid transformations. J. Comput. Chem. 35 (10) (2014)
Mazen Ahmad, Olga V. Kalinina, Thomas Lengauer
Entropy gain due to water release upon ligand binding. J. Cheminformatics 6 (S-1) (2014)
Matthias Dietzen, Elena Zotenko, Andreas Hildebrandt, Thomas Lengauer
Correction to On the Applicability of Elastic Network Normal Modes in Small-Molecule Docking. J. Chem. Inf. Model. 54 (12) (2014)
Daniel Becker, Pavlo Lutsik, Peter Ebert, Christoph Bock, Thomas Lengauer, Jörn Walter
BiQ Analyzer HiMod: an interactive software tool for high-throughput locus-specific analysis of 5-methylcytosine and its oxidized derivatives. Nucleic Acids Res. 42 (Webserver-Issue) (2014)
Laura Tolosi, Jessica Theißen, Konstantin Halachev, Barbara Hero, Frank Berthold, Thomas Lengauer
A method for finding consensus breakpoints in the cancer genome from copy number data. Bioinform. 29 (14) (2013)
Katarzyna Bozek, Thomas Lengauer, Saleta Sierra, Rolf Kaiser, Francisco S. Domingues
Analysis of Physicochemical and Structural Properties Determining HIV-1 Coreceptor Usage. PLoS Comput. Biol. 9 (3) (2013)
Thomas Lengauer, Ruth Nussinov
. PLoS Comput. Biol. 9 (3) (2013)
Sven-Eric Schelhorn, Matthias Fischer, Laura Tolosi, Janine Altmüller, Peter Nürnberg, Herbert Pfister, Thomas Lengauer, Frank Berthold
Sensitive Detection of Viral Transcripts in Human Tumor Transcriptomes. PLoS Comput. Biol. 9 (10) (2013)
Matthias Dietzen, Elena Zotenko, Andreas Hildebrandt, Thomas Lengauer
On the Applicability of Elastic Network Normal Modes in Small-Molecule Docking. J. Chem. Inf. Model. 52 (3) (2012)
Jasmina Bogojeska, Daniel Stöckel, Maurizio Zazzi, Rolf Kaiser, Francesca Incardona, Michal Rosen-Zvi, Thomas Lengauer
History-alignment models for bias-aware prediction of virological response to HIV combination therapy. AISTATS (2012)
Nico Pfeifer, Thomas Lengauer
Improving HIV coreceptor usage prediction in the clinic using hints from next-generation sequencing data. Bioinform. 28 (18) (2012)
Burkhard Rost, Terry Gaasterland, Thomas Lengauer, Michal Linial, Scott Markel, B. J. Morrison McKay, Reinhard Schneider, Paul Horton, Janet Kelso
Paving the future: finding suitable ISMB venues. Bioinform. 28 (19) (2012)
Pavlo Lutsik, Lars Feuerbach, Julia Arand, Thomas Lengauer, Jörn Walter, Christoph Bock
BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing. Nucleic Acids Res. 39 (Web-Server-Issue) (2011)
Martin Däumer, Rolf Kaiser, Rolf Klein, Thomas Lengauer, Bernhard Thiele, Alexander Thielen
Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis. BMC Medical Informatics Decis. Mak. 11 (2011)
Laura Tolosi, Thomas Lengauer
Classification with correlated features: unreliability of feature ranking and solutions. Bioinform. 27 (14) (2011)
Kirsten Roomp, Iris Antes, Thomas Lengauer
Predicting MHC class I epitopes in large datasets. BMC Bioinform. 11 (2010)
André Altmann, Laura Tolosi, Oliver Sander, Thomas Lengauer
Permutation importance: a corrected feature importance measure. Bioinform. 26 (10) (2010)
Andreas Schlicker, Thomas Lengauer, Mario Albrecht
Improving disease gene prioritization using the semantic similarity of Gene Ontology terms. Bioinform. 26 (18) (2010)
Thomas Lengauer, André Altmann, Alexander Thielen, Rolf Kaiser
Chasing the AIDS virus. Commun. ACM 53 (3) (2010)
Jasmina Bogojeska, Steffen Bickel, André Altmann, Thomas Lengauer
Dealing with sparse data in predicting outcomes of HIV combination therapies. Bioinform. 26 (17) (2010)
Dorothea Emig, Nathan Salomonis, Jan Baumbach, Thomas Lengauer, Bruce R. Conklin, Mario Albrecht
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data. Nucleic Acids Res. 38 (Web-Server-Issue) (2010)
Thomas Lengauer, André Altmann, Alexander Thielen
Bioinformatische Unterstützung der Auswahl von HIV-Therapien. Inform. Spektrum 32 (4) (2009)
Hagen Blankenburg, Robert D. Finn, Andreas Prlic, Andrew M. Jenkinson, Fidel Ramírez, Dorothea Emig, Sven-Eric Schelhorn, Joachim Büch, Thomas Lengauer, Mario Albrecht
DASMI: exchanging, annotating and assessing molecular interaction data. Bioinform. 25 (10) (2009)
Juliane Perner, André Altmann, Thomas Lengauer
Semi-Supervised Learning for Improving Prediction of HIV Drug Resistance. GCB (2009)
Dorothea Emig, Melissa S. Cline, Karsten Klein, Anne Kunert, Petra Mutzel, Thomas Lengauer, Mario Albrecht
Integrative Visual Analysis of the Effects of Alternative Splicing on Protein Domain Interaction Networks. J. Integr. Bioinform. 5 (2) (2008)
Oliver Sander, Francisco S. Domingues, Hongbo Zhu, Thomas Lengauer, Ingolf Sommer
Structural Descriptors of Protein-Protein Binding Sites. APBC (2008)
Christoph Bock, Thomas Lengauer
Computational epigenetics. Bioinform. 24 (1) (2008)
Jasmina Bogojeska, Thomas Lengauer, Jörg Rahnenführer
Stability analysis of mixtures of mutagenetic trees. BMC Bioinform. 9 (2008)
Dorothea Emig, Melissa S. Cline, Thomas Lengauer, Mario Albrecht
Integrating expression data with domain interaction networks. Bioinform. 24 (21) (2008)
Andreas Schlicker, Fidel Ramírez, Jörg Rahnenführer, Carola Huthmacher, Alejandro Pironti, Francisco S. Domingues, Thomas Lengauer, Mario Albrecht
Applications of semantic similarity measures. Ontologies and Text Mining for Life Sciences (2008)
Steffen Bickel, Jasmina Bogojeska, Thomas Lengauer, Tobias Scheffer
Multi-task learning for HIV therapy screening. ICML (2008)
Nils Weinhold, Oliver Sander, Francisco S. Domingues, Thomas Lengauer, Ingolf Sommer
Local Function Conservation in Sequence and Structure Space. PLoS Comput. Biol. 4 (7) (2008)
Jasmina Bogojeska, Adrian Alexa, André Altmann, Thomas Lengauer, Jörg Rahnenführer
Rtreemix: an R package for estimating evolutionary pathways and genetic progression scores. Bioinform. 24 (20) (2008)
Yassen Assenov, Fidel Ramírez, Sven-Eric Schelhorn, Thomas Lengauer, Mario Albrecht
Computing topological parameters of biological networks. Bioinform. 24 (2) (2008)
Sven-Eric Schelhorn, Thomas Lengauer, Mario Albrecht
An integrative approach for predicting interactions of protein regions. ECCB (2008)
Michal Rosen-Zvi, André Altmann, Mattia C. F. Prosperi, Ehud Aharoni, Hani Neuvirth, Anders Sönnerborg, Eugen Schülter, Daniel Struck, Yardena Peres, Francesca Incardona, Rolf Kaiser, Maurizio Zazzi, Thomas Lengauer
Selecting anti-HIV therapies based on a variety of genomic and clinical factors. ISMB (2008)
Ingolf Sommer, Oliver Müller, Francisco S. Domingues, Oliver Sander, Joachim Weickert, Thomas Lengauer
Moment invariants as shape recognition technique for comparing protein binding sites. Bioinform. 23 (23) (2007)
Andreas Schlicker, Carola Huthmacher, Fidel Ramírez, Thomas Lengauer, Mario Albrecht
Functional evaluation of domain-domain interactions and human protein interaction networks. Bioinform. 23 (7) (2007)
Thomas Lengauer, B. J. Morrison McKay, Burkhard Rost
ISMB/ECCB 2007: The Premier Conference on Computational Biology. PLoS Comput. Biol. 3 (5) (2007)
Francisco S. Domingues, Jörg Rahnenführer, Thomas Lengauer
Conformational analysis of alternative protein structures. Bioinform. 23 (23) (2007)
Oliver Sander, Tobias Sing, Ingolf Sommer, Andrew J. Low, Peter K. Cheung, P. Richard Harrigan, Thomas Lengauer, Francisco S. Domingues
Structural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage. PLoS Comput. Biol. 3 (3) (2007)
Christoph Bock, Jörn Walter, Martina Paulsen, Thomas Lengauer
CpG Island Mapping by Epigenome Prediction. PLoS Comput. Biol. 3 (6) (2007)
Ingolf Sommer, Stefano Toppo, Oliver Sander, Thomas Lengauer, Silvio C. E. Tosatto
Improving the quality of protein structure models by selecting from alignment alternatives. BMC Bioinform. 7 (2006)
Oliver Sander, Ingolf Sommer, Thomas Lengauer
Local protein structure prediction using discriminative models. BMC Bioinform. 7 (2006)
Andrew E. Torda, Thomas Lengauer
Editorial. Bioinform. 22 (10) (2006)
Jochen Maydt, Thomas Lengauer
Recco: recombination analysis using cost optimization. Bioinform. 22 (9) (2006)
Andreas Steffen, Andreas Kämper, Thomas Lengauer
Flexible Docking of Ligands into Synthetic Receptors Using a Two-Sided Incremental Construction Algorithm. J. Chem. Inf. Model. 46 (4) (2006)
Adrian Alexa, Jörg Rahnenführer, Thomas Lengauer
Improved scoring of functional groups from gene expression data by decorrelating GO graph structure. Bioinform. 22 (13) (2006)
Dirk Neumann, Oliver Kohlbacher, Christian Merkwirth, Thomas Lengauer
A Fully Computational Model for Predicting Percutaneous Drug Absorption. J. Chem. Inf. Model. 46 (1) (2006)
Iris Antes, Shirley W. I. Siu, Thomas Lengauer
DynaPred: A structure and sequence based method for the prediction of MHC class I binding peptide sequences and conformations. ISMB (Supplement of Bioinformatics) (2006)
Hongbo Zhu, Francisco S. Domingues, Ingolf Sommer, Thomas Lengauer
NOXclass: prediction of protein-protein interaction types. BMC Bioinform. 7 (2006)
Burkhard Heil, Jost Ludwig, Hella Lichtenberg-Fraté, Thomas Lengauer
Computational recognition of potassium channel sequences. Bioinform. 22 (13) (2006)
Andreas Schlicker, Carola Huthmacher, Fidel Ramírez, Thomas Lengauer, Mario Albrecht
Functional Evaluation of Domain-Domain Interactions and Human Protein Interaction Networks. German Conference on Bioinformatics (2006)
Andreas Kämper, Joannis Apostolakis, Matthias Rarey, Christel M. Marian, Thomas Lengauer
Fully Automated Flexible Docking of Ligands into Flexible Synthetic Receptors Using Forward and Inverse Docking Strategies. J. Chem. Inf. Model. 46 (2) (2006)
Andreas Schlicker, Francisco S. Domingues, Jörg Rahnenführer, Thomas Lengauer
A new measure for functional similarity of gene products based on Gene Ontology. BMC Bioinform. 7 (2006)
Kirsten Roomp, Niko Beerenwinkel, Tobias Sing, Eugen Schülter, Joachim Büch, Saleta Sierra-Aragon, Martin Däumer, Daniel Hoffmann, Rolf Kaiser, Thomas Lengauer, Joachim Selbig
Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIV. DILS (2006)
Jörg Rahnenführer, Niko Beerenwinkel, Wolfgang A. Schulz, Christian Hartmann, Andreas von Deimling, Bernd Wullich, Thomas Lengauer
Estimating cancer survival and clinical outcome based on genetic tumor progression scores. Bioinform. 21 (10) (2005)
Christoph Bock, Sabine Reither, Thomas Mikeska, Martina Paulsen, Jörn Walter, Thomas Lengauer
BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing. Bioinform. 21 (21) (2005)
Thomas Lengauer
The DFG Priority Program "Informatics Methods for the Analysis and Interpretation of Large Genomic Datasets". it Inf. Technol. 47 (4) (2005)
Niko Beerenwinkel, Jörg Rahnenführer, Rolf Kaiser, Daniel Hoffmann, Joachim Selbig, Thomas Lengauer
Mtreemix: a software package for learning and using mixture models of mutagenetic trees. Bioinform. 21 (9) (2005)
Mario Albrecht, Carola Huthmacher, Silvio C. E. Tosatto, Thomas Lengauer
Decomposing protein networks into domain-domain interactions. ECCB/JBI (2005)
Christian Merkwirth, Thomas Lengauer
Automatic Generation of Complementary Descriptors with Molecular Graph Networks. J. Chem. Inf. Model. 45 (5) (2005)
Tobias Sing, Oliver Sander, Niko Beerenwinkel, Thomas Lengauer
ROCR: visualizing classifier performance in R. Bioinform. 21 (20) (2005)
Iris Antes, Christian Merkwirth, Thomas Lengauer
POEM: Parameter Optimization Using Ensemble Methods: Application to Target Specific Scoring Functions. J. Chem. Inf. Model. 45 (5) (2005)
Tobias Sing, Niko Beerenwinkel, Thomas Lengauer, Valentina Svicher, Francesca Ceccherini-Silberstein, Carlo-Federico Perno
Supervised and Unsupervised Approaches for Analyzing Covariation and Phenotypic Impact of HIV Drug Resistance Mutations. LWA (2005)
Andreas Hahn, Jörg Rahnenführer, Priti Talwar, Thomas Lengauer
Confirmation of human protein interaction data by human expression data. BMC Bioinform. 6 (2005)
Tobias Sing, Valentina Svicher, Niko Beerenwinkel, Francesca Ceccherini-Silberstein, Martin Däumer, Rolf Kaiser, Hauke Walter, Klaus Korn, Daniel Hoffmann, Mark Oette, Jürgen K. Rockstroh, Gerd Fätkenheuer, Carlo-Federico Perno, Thomas Lengauer
Characterization of Novel HIV Drug Resistance Mutations Using Clustering, Multidimensional Scaling and SVM-Based Feature Ranking. PKDD (2005)
Niko Beerenwinkel, Tobias Sing, Thomas Lengauer, Jörg Rahnenführer, Kirsten Roomp, Igor Savenkov, Roman Fischer, Daniel Hoffmann, Joachim Selbig, Klaus Korn, Hauke Walter, Thomas Berg, Patrick Braun, Gerd Fätkenheuer, Mark Oette, Jürgen K. Rockstroh, Bernd Kupfer, Rolf Kaiser, Martin Däumer
Computational methods for the design of effective therapies against drug resistant HIV strains. Bioinform. 21 (21) (2005)
Niko Beerenwinkel, Jörg Rahnenführer, Martin Däumer, Daniel Hoffmann, Rolf Kaiser, Joachim Selbig, Thomas Lengauer
Learning Multiple Evolutionary Pathways from Cross-Sectional Data. J. Comput. Biol. 12 (6) (2005)
Torsten Crass, Iris Antes, Rico Basekow, Peer Bork, Christian Buning, Maik Christensen, Holger Claussen, Christian Ebeling, Peter Ernst, Valérie Gailus-Durner, Karl-Heinz Glatting, Rolf Gohla, Frank Gößling, Korbinian Grote, Karsten R. Heidtke, Alexander Herrmann, Sean O'Keeffe, O. Kießlich, Sven Kolibal, Jan O. Korbel, Thomas Lengauer, Ines Liebich, Mark van der Linden, Hannes Luz, Kathrin Meissner, Christian von Mering, Heinz-Theodor Mevissen, Hans-Werner Mewes, Holger Michael, Martin Mokrejs, Tobias Müller, Heike Pospisil, Matthias Rarey, Jens G. Reich, Ralf Schneider, Dietmar Schomburg, Steffen Schulze-Kremer, Knut Schwarzer, Ingolf Sommer, Stephan Springstubbe, Sándor Suhai, Gnanasekaran Thoppae, Martin Vingron, Jens Warfsmann, Thomas Werner, Daniel Wetzler, Edgar Wingender, Ralf Zimmer
The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources. Bioinform. 20 (2) (2004)
Niko Beerenwinkel, Jörg Rahnenführer, Martin Däumer, Daniel Hoffmann, Rolf Kaiser, Joachim Selbig, Thomas Lengauer
Learning multiple evolutionary pathways from cross-sectional data. RECOMB (2004)
Tobias Sing, Niko Beerenwinkel, Thomas Lengauer
Learning Mixtures of Localized Rules by Maximizing the Area Under the ROC Curve. ROCAI (2004)
Ingolf Sommer, Jörg Rahnenführer, Francisco S. Domingues, U. de Lichtenberg, Thomas Lengauer
Predicting protein structure classes from function predictions. Bioinform. 20 (5) (2004)
Christian Merkwirth, Harald Mauser, Tanja Schulz-Gasch, Olivier Roche, Martin Stahl, Thomas Lengauer
Ensemble Methods for Classification in Cheminformatics. J. Chem. Inf. Model. 44 (6) (2004)
Niklas von Öhsen, Ingolf Sommer, Ralf Zimmer, Thomas Lengauer
Arby: automatic protein structure prediction using profile-profile alignment and confidence measures. Bioinform. 20 (14) (2004)
Niko Beerenwinkel, Thomas Lengauer, Martin Däumer, Rolf Kaiser, Hauke Walter, Klaus Korn, Daniel Hoffmann, Joachim Selbig
Methods for optimizing antiviral combination therapies. ISMB (Supplement of Bioinformatics) (2003)
Mario Albrecht, Thomas Lengauer
Pyranose Oxidase Identified as A Member of the GMC Oxidoreductase Family. Bioinform. 19 (10) (2003)
Alexander Zien, Juliane Fluck, Ralf Zimmer, Thomas Lengauer
Microarrays: How Many Do You Need? J. Comput. Biol. 10 (3/4) (2003)
Niko Beerenwinkel, Martin Däumer, Mark Oette, Klaus Korn, Daniel Hoffmann, Rolf Kaiser, Thomas Lengauer, Joachim Selbig, Hauke Walter
Geno2pheno: estimating phenotypic drug resistance from HIV-1 genotypes. Nucleic Acids Res. 31 (13) (2003)
Mario Albrecht, Thomas Lengauer, Stefan Schreiber
Disease-associated variants in PYPAF1 and NOD2 result in similar alterations of conserved sequence. Bioinform. 19 (17) (2003)
Marcus Peinado, Thomas Lengauer
Parallel 'go with the winners' algorithms in distributed memory models. J. Parallel Distributed Comput. 63 (9) (2003)
Thomas Lengauer
Analyzing resistance phenomena in HIV with bioinformatics methods. ECCB (2003)
Ingolf Sommer, Alexander Zien, Niklas von Öhsen, Ralf Zimmer, Thomas Lengauer
Confidence measures for protein fold recognition. Bioinform. 18 (6) (2002)
Jan Freudenberg, Ralf Zimmer, Daniel Hanisch, Thomas Lengauer
A hypergraph-based method for unification of existing protein structure- and sequence-families. Silico Biol. 2 (3) (2002)
Daniel Hanisch, Ralf Zimmer, Thomas Lengauer
ProML - the Protein Markup Language for specification of protein sequences, structures and families. Silico Biol. 2 (3) (2002)
Daniel Hanisch, Alexander Zien, Ralf Zimmer, Thomas Lengauer
Co-clustering of biological networks and gene expression data. ISMB (2002)
Sally A. Hindle, Matthias Rarey, Christian Buning, Thomas Lengauer
Flexible docking under pharmacophore type constraints. J. Comput. Aided Mol. Des. 16 (2) (2002)
Mario Albrecht, Daniel Hanisch, Ralf Zimmer, Thomas Lengauer
Improving fold recognition of protein threading by experimental distance constraints. Silico Biol. 2 (3) (2002)

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Publication Activity (10 Years)

Top Topics

Top Venues

Thomas Lengauer