Patrick B. Ryan

Publication Activity (10 Years)

Years Active: 2010-2023
Publications (10 Years): 60

Top Topics

Observational Data

Prognostic Models

Electronic Health Records

Top Venues

J. Am. Medical Informatics Assoc.

J. Biomed. Informatics

BMC Medical Informatics Decis. Mak.

Publications

Tiffany J. Callahan, Adrianne L. Stefanski, Jordan M. Wyrwa, Chenjie Zeng, Anna Ostropolets, Juan M. Banda, William A. Baumgartner Jr., Richard D. Boyce, Elena Casiraghi, Ben D. Coleman, Janine H. Collins, Sara J. Deakyne Davies, James A. Feinstein, Asiyah Y. Lin, Blake Martin, Nicolas A. Matentzoglu, Daniella Meeker, Justin T. Reese, Jessica Sinclair, Sanya Bathla Taneja, Katy E. Trinkley, Nicole A. Vasilevsky, Andrew E. Williams, Xingmin Aaron Zhang, Joshua C. Denny, Patrick B. Ryan, George Hripcsak, Tellen D. Bennett, Melissa A. Haendel, Peter N. Robinson, Lawrence E. Hunter, Michael G. Kahn
Ontologizing health systems data at scale: making translational discovery a reality. npj Digit. Medicine 6 (2023)
Anna Ostropolets, Yasser Albogami, Mitchell Conover, Juan M. Banda, William A. Baumgartner Jr., Clair Blacketer, Priyamvada Desai, Scott L. DuVall, Stephen P. Fortin, James P. Gilbert, Asieh Golozar, Joshua Ide, Andrew S. Kanter, David M. Kern, Chungsoo Kim, Lana Y. H. Lai, Chenyu Li, Feifan Liu, Kristine E. Lynch, Evan Minty, Maria Inês Neves, Ding Quan Ng, Tontel Obene, Victor Pera, Nicole Pratt, Gowtham Rao, Nadav Rappoport, Ines Reinecke, Paola Saroufim, Azza Shoaibi, Katherine Simon, Marc A. Suchard, Joel N. Swerdel, Erica A. Voss, James Weaver, Linying Zhang, George Hripcsak, Patrick B. Ryan
Reproducible variability: assessing investigator discordance across 9 research teams attempting to reproduce the same observational study. J. Am. Medical Informatics Assoc. 30 (5) (2023)
Alexandros Rekkas, David van Klaveren, Patrick B. Ryan, Ewout W. Steyerberg, David M. Kent, Peter R. Rijnbeek
A standardized framework for risk-based assessment of treatment effect heterogeneity in observational healthcare databases. npj Digit. Medicine 6 (2023)
Stephen P. Fortin, Jenna Reps, Patrick B. Ryan
Correction to: Adaptation and validation of a coding algorithm for the Charlson Comorbidity Index in administrative claims data using the SNOMED CT standardized vocabulary. BMC Medical Informatics Decis. Mak. 23 (1) (2023)
Vipina Kuttichi Keloth, Juan M. Banda, Michael J. Gurley, Paul M. Heider, Georgina Kennedy, Hongfang Liu, Feifan Liu, Timothy A. Miller, Karthik Natarajan, Olga V. Patterson, Yifan Peng, Kalpana Raja, Ruth M. Reeves, Masoud Rouhizadeh, Jianlin Shi, Xiaoyan Wang, Yanshan Wang, Wei-Qi Wei, Andrew E. Williams, Rui Zhang, Rimma Belenkaya, Christian G. Reich, Clair Blacketer, Patrick B. Ryan, George Hripcsak, Noémie Elhadad, Hua Xu
Representing and utilizing clinical textual data for real world studies: An OHDSI approach. J. Biomed. Informatics 142 (2023)
Qiong Wu, Martijn J. Schuemie, Marc A. Suchard, Patrick B. Ryan, George Hripcsak, Charles A. Rohde, Yong Chen
Padé approximant meets federated learning: A nearly lossless, one-shot algorithm for evidence synthesis in distributed research networks with rare outcomes. J. Biomed. Informatics 145 (2023)
Tiffany J. Callahan, Ignacio J. Tripodi, Adrianne L. Stefanski, Luca Cappelletti, Sanya Bathla Taneja, Jordan M. Wyrwa, Elena Casiraghi, Nicolas A. Matentzoglu, Justin T. Reese, Jonathan C. Silverstein, Charles Tapley Hoyt, Richard D. Boyce, Scott A. Malec, Deepak R. Unni, Marcin P. Joachimiak, Peter N. Robinson, Christopher J. Mungall, Emanuele Cavalleri, Tommaso Fontana, Giorgio Valentini, Marco Mesiti, Lucas A. Gillenwater, Brook E. Santangelo, Nicole A. Vasilevsky, Robert Hoehndorf, Tellen D. Bennett, Patrick B. Ryan, George Hripcsak, Michael G. Kahn, Michael Bada, William A. Baumgartner Jr., Lawrence E. Hunter
An Open-Source Knowledge Graph Ecosystem for the Life Sciences. CoRR (2023)
Anna Ostropolets, George Hripcsak, Syed A Husain, Lauren R. Richter, Matthew E. Spotnitz, Ahmed Elhussein, Patrick B. Ryan
Scalable and interpretable alternative to chart review for phenotype evaluation using standardized structured data from electronic health records. J. Am. Medical Informatics Assoc. 31 (1) (2023)
Joel N. Swerdel, Martijn J. Schuemie, Gayle Murray, Patrick B. Ryan
PheValuator 2.0: Methodological improvements for the PheValuator approach to semi-automated phenotype algorithm evaluation. J. Biomed. Informatics 135 (2022)
Stephen P. Fortin, Jenna Reps, Patrick B. Ryan
Adaptation and validation of a coding algorithm for the Charlson Comorbidity Index in administrative claims data using the SNOMED CT standardized vocabulary. BMC Medical Informatics Decis. Mak. 22 (1) (2022)
Jenna Marie Reps, Ross D. Williams, Martijn J. Schuemie, Patrick B. Ryan, Peter R. Rijnbeek
Learning patient-level prediction models across multiple healthcare databases: evaluation of ensembles for increasing model transportability. BMC Medical Informatics Decis. Mak. 22 (1) (2022)
Luis H. John, Jan A. Kors, Jenna Marie Reps, Patrick B. Ryan, Peter R. Rijnbeek
Logistic regression models for patient-level prediction based on massive observational data: Do we need all data? Int. J. Medical Informatics 163 (2022)
Chi Yuan, Patrick B. Ryan, Casey N. Ta, Jae Hyun Kim, Ziran Li, Chunhua Weng
From clinical trials to clinical practice: How long are drugs tested and then used by patients? J. Am. Medical Informatics Assoc. 28 (11) (2021)
Jenna Marie Reps, Peter R. Rijnbeek, Alana Cuthbert, Patrick B. Ryan, Nicole Pratt, Martijn J. Schuemie
An empirical analysis of dealing with patients who are lost to follow-up when developing prognostic models using a cohort design. BMC Medical Informatics Decis. Mak. 21 (1) (2021)
Amelia J. Averitt, Patrick B. Ryan, Chunhua Weng, Adler J. Perotte
A conceptual framework for external validity. J. Biomed. Informatics 121 (2021)
Martijn J. Schuemie, Patrick B. Ryan, Nicole Pratt, Ruijun Chen, Seng Chan You, Harlan M. Krumholz, David Madigan, George Hripcsak, Marc A. Suchard
Erratum to: Large-Scale Evidence Generation and Evaluation across a Network of Databases (LEGEND): Assessing Validity Using Hypertension as a Case Study. J. Am. Medical Informatics Assoc. 28 (1) (2021)
Anna Ostropolets, Patrick B. Ryan, George Hripcsak
PHenotype Observed Entity Baseline Endorsements (PHOEBE) - recommender system for concept selection in phenotype algorithm development. AMIA (2021)
Jenna Marie Reps, Patrick B. Ryan, Peter R. Rijnbeek, Martijn J. Schuemie
Design matters in patient-level prediction: evaluation of a cohort vs. case-control design when developing predictive models in observational healthcare datasets. J. Big Data 8 (1) (2021)
Clair Blacketer, Frank J. DeFalco, Patrick B. Ryan, Peter R. Rijnbeek
Increasing trust in real-world evidence through evaluation of observational data quality. J. Am. Medical Informatics Assoc. 28 (10) (2021)
Jae Hyun Kim, Casey N. Ta, Cong Liu, Cynthia Sung, Alex M. Butler, Latoya A. Stewart, Lyudmila Ena, James R. Rogers, Junghwan Lee, Anna Ostropolets, Patrick B. Ryan, Hao Liu, Shing M. Lee, Mitchell S. V. Elkind, Chunhua Weng
Towards clinical data-driven eligibility criteria optimization for interventional COVID-19 clinical trials. J. Am. Medical Informatics Assoc. 28 (1) (2021)
Chao Pang, Ruijun Chen, Harry Reyes Nieva, Krishna Kalluri, Tony Sun, Xinzhuo Jiang, Victor Alfonso Rodriguez, Patrick B. Ryan, Karthik Natarajan
Characterization and Comparison of Embedding Algorithms for Phenotyping across a Network of Observational Databases. AMIA (2020)
Anna Ostropolets, Christian G. Reich, Patrick B. Ryan, Chunhua Weng, Anthony Molinaro, Frank J. DeFalco, Jitendra Jonnagaddala, Siaw-Teng Liaw, Hokyun Jeon, Rae Woong Park, Matthew E. Spotnitz, Karthik Natarajan, Kristin Kostka, George Argyriou, Robert T. Miller, Andrew E. Williams, Evan Minty, José D. Posada, George Hripcsak
Characterizing database granularity using SNOMED-CT hierarchy. AMIA (2020)
Luis H. John, Jan A. Kors, Jenna Marie Reps, Patrick B. Ryan, Peter R. Rijnbeek
How little data do we need for patient-level prediction? CoRR (2020)
Anna Ostropolets, Christian G. Reich, Patrick B. Ryan, Ning Shang, George Hripcsak, Chunhua Weng
Adapting electronic health records-derived phenotypes to claims data: Lessons learned in using limited clinical data for phenotyping. J. Biomed. Informatics 102 (2020)
Martijn J. Schuemie, Patrick B. Ryan, Nicole Pratt, Ruijun Chen, Seng Chan You, Harlan M. Krumholz, David Madigan, George Hripcsak, Marc A. Suchard
Principles of Large-scale Evidence Generation and Evaluation across a Network of Databases (LEGEND). J. Am. Medical Informatics Assoc. 27 (8) (2020)
James R. Rogers, Junghwan Lee, Ziheng Zhou, Patrick B. Ryan, George Hripcsak, Chunhua Weng
Contemporary Use of Real World Data for Clinical Trial Conduct. AMIA (2020)
Ruijun Chen, Martijn J. Schuemie, Marc A. Suchard, Anna Ostropolets, Linying Zhang, Patrick B. Ryan, George Hripcsak
Evaluation of Large-scale Propensity Score Modeling and Covariate Balance on Potential Unmeasured Confounding in Observational Research. AMIA (2020)
Amelia J. Averitt, Chunhua Weng, Patrick B. Ryan, Adler J. Perotte
Translating evidence into practice: eligibility criteria fail to eliminate clinically significant differences between real-world and study populations. npj Digit. Medicine 3 (2020)
Martijn J. Schuemie, Patrick B. Ryan, Nicole Pratt, Ruijun Chen, Seng Chan You, Harlan M. Krumholz, David Madigan, George Hripcsak, Marc A. Suchard
Large-scale evidence generation and evaluation across a network of databases (LEGEND): assessing validity using hypertension as a case study. J. Am. Medical Informatics Assoc. 27 (8) (2020)
Victor Alfonso Rodriguez, Tony Sun, Phyllis Thangaraj, Chao Pang, Krishna Kalluri, Xinzhuo Jiang, Karthik Natarajan, Patrick B. Ryan, Anna Ostropolets, Ruijun Chen
Phenotype Concept Set Construction from Concept Pair Likelihoods. AMIA (2020)
Jenna Marie Reps, Peter R. Rijnbeek, Patrick B. Ryan
Supplementing claims data analysis using self-reported data to develop a probabilistic phenotype model for current smoking status. J. Biomed. Informatics 97 (2019)
Chi Yuan, Patrick B. Ryan, Casey N. Ta, Yixuan Guo, Ziran Li, Jill Hardin, Rupa Makadia, Peng Jin, Ning Shang, Tian Kang, Chunhua Weng
Criteria2Query: a natural language interface to clinical databases for cohort definition. J. Am. Medical Informatics Assoc. 26 (4) (2019)
Fernanda C. Polubriaginof, Patrick B. Ryan, Hojjat Salmasian, Andrea W. Shapiro, Adler J. Perotte, Monika M. Safford, George Hripcsak, Shaun Smith, Nicholas P. Tatonetti, David K. Vawdrey
Challenges with quality of race and ethnicity data in observational databases. J. Am. Medical Informatics Assoc. 26 (8-9) (2019)
Joel N. Swerdel, George Hripcsak, Patrick B. Ryan
PheValuator: Development and evaluation of a phenotype algorithm evaluator. J. Biomed. Informatics 97 (2019)
Noémie Elhadad, Iñigo Urteaga, Alison Callahan, Jenna Reps, Patrick B. Ryan
Learning Across a Healthcare Data Network to Improve Model Robustness and Evidence Reliability. AMIA (2019)
Anando Sen, Andrew Goldstein, Shreya Chakrabarti, Ning Shang, Tian Kang, Anil Yaman, Patrick B. Ryan, Chunhua Weng
The representativeness of eligible patients in type 2 diabetes trials: a case study using GIST 2.0. J. Am. Medical Informatics Assoc. 25 (3) (2018)
Mary Regina Boland, Pradipta Parhi, Li Li, Riccardo Miotto, Robert J. Carroll, Usman Iqbal, Phung-Anh (Alex) Nguyen, Martijn J. Schuemie, Seng Chan You, Donahue Smith, Sean Mooney, Patrick B. Ryan, Yu-Chuan (Jack) Li, Rae Woong Park, Joshua C. Denny, Joel T. Dudley, George Hripcsak, Pierre Gentine, Nicholas P. Tatonetti
Uncovering exposures responsible for birth season - disease effects: a global study. J. Am. Medical Informatics Assoc. 25 (3) (2018)
George Hripcsak, Matthew E. Levine, Ning Shang, Patrick B. Ryan
Effect of vocabulary mapping for conditions on phenotype cohorts. J. Am. Medical Informatics Assoc. 25 (12) (2018)
Jenna Marie Reps, Martijn J. Schuemie, Marc A. Suchard, Patrick B. Ryan, Peter R. Rijnbeek
Design and implementation of a standardized framework to generate and evaluate patient-level prediction models using observational healthcare data. J. Am. Medical Informatics Assoc. 25 (8) (2018)
Ruijun Chen, Patrick B. Ryan, Karthik Natarajan, Thomas Falconer, Christian G. Reich, Rohit Vashisht, Nigam Shah, George Hripcsak
Treatment Pathways in Patients with Cancer Using a Large-scale Observational Data Network. AMIA (2018)
Cole Brokamp, Chris Wolfe, Todd Lingren, John Harley, Patrick B. Ryan
Decentralized and reproducible geocoding and characterization of community and environmental exposures for multisite studies. J. Am. Medical Informatics Assoc. 25 (3) (2018)
Erica A. Voss, Richard D. Boyce, Patrick B. Ryan, Johan van der Lei, Peter R. Rijnbeek, Martijn J. Schuemie
Accuracy of an automated knowledge base for identifying drug adverse reactions. J. Biomed. Informatics 66 (2017)
Richard D. Boyce, Erica A. Voss, Vojtech Huser, Lee Evans, Christian G. Reich, Jon D. Duke, Nicholas P. Tatonetti, Tal Lorberbaum, Michel Dumontier, Manfred Hauben, Magnus Wallberg, Lili Peng, Sara Dempster, Yongqun He, Anthony G. Sena, Vassilis Koutkias, Pantelis Natsiavas, Patrick B. Ryan
Large-scale adverse effects related to treatment evidence standardization (LAERTES): an open scalable system for linking pharmacovigilance evidence sources with clinical data. J. Biomed. Semant. 8 (1) (2017)
Jon D. Duke, George Hripcsak, Patrick B. Ryan, Nigam Shah
From Large-Scale Network Analytics to Clinical Solutions in OHDSI. AMIA (2017)
Robert Moskovitch, Fernanda Polubriaginof, Aviram Weiss, Patrick B. Ryan, Nicholas P. Tatonetti
Procedure prediction from symbolic Electronic Health Records via time intervals analytics. J. Biomed. Informatics 75 (2017)
Vivienne J. Zhu, J. Marc Overhage, Qianli Ma, Patrick B. Ryan
The Impact of Censoring Drug Switching in Medication Adherence Measures of Chronic Single Ingredient Oral Drugs. MedInfo (2017)
Chi Yuan, Patrick B. Ryan, Yixuan Guo, Peng Jin, Tian Kang, Chunhua Weng
Criteria2Query: Automatically Transforming Clinical Research Eligibility Criteria Text to OMOP Common Data Model (CDM)-based Cohort Queries. AMIA (2017)
Jianying Hu, Nigam H. Shah, Bradley A. Malin, Patrick B. Ryan, Anil Jain
Big Data for Healthcare and Life Sciences: Learning Useful Insights from Imperfect Data. AMIA (2016)
Ning Shang, George Hripcsak, Patrick B. Ryan, Chunhua Weng
The Applicability of an EHR Phenotype for Cohort Identification. CRI (2016)
Jon D. Duke, George Hripcsak, Nigam Shah, Patrick B. Ryan, Vojtech Huser
Observational Health Data Sciences and Informatics (OHDSI): A Rapidly Growing International Network for Open Science and Data Analytics in Healthcare. CRI (2016)
Anando Sen, Shreya Chakrabarti, Andrew Goldstein, Shuang Wang, Patrick B. Ryan, Chunhua Weng
GIST 2.0: A scalable multi-trait metric for quantifying population representativeness of individual clinical studies. J. Biomed. Informatics 63 (2016)
Trevor R. Shaddox, Patrick B. Ryan, Martijn J. Schuemie, David Madigan, Marc A. Suchard
Hierarchical models for multiple, rare outcomes using massive observational healthcare databases. Stat. Anal. Data Min. 9 (4) (2016)
Jon D. Duke, Nigam H. Shah, George Hripcsak, Patrick B. Ryan
Ensuring Reproducibility in Observational Research: Building and Sharing Knowledge Resources in the OHDSI Network. AMIA (2016)
Zhe He, Patrick B. Ryan, Julia Hoxha, Shuang Wang, Simona Carini, Ida Sim, Chunhua Weng
Multivariate analysis of the population representativeness of related clinical studies. J. Biomed. Informatics 60 (2016)
Jon D. Duke, Frank J. DeFalco, Chris Knoll, Vojtech Huser, Richard D. Boyce, Patrick B. Ryan
OHDSI: An Open-Source Platform for Observational Data Analytics and Collaborative Research. AMIA (2015)
Jon D. Duke, George Hripcsak, Nigam Shah, Patrick B. Ryan
The Value of an Open-Source Observational Research Collaboratory: Results from the OHDSI Initiative. AMIA (2015)
Zach Shahn, Patrick B. Ryan, David Madigan
Predicting health outcomes from high-dimensional longitudinal health histories using relational random forests. Stat. Anal. Data Min. 8 (2) (2015)
Erica A. Voss, Rupa Makadia, Amy Matcho, Qianli Ma, Chris Knoll, Martijn J. Schuemie, Frank J. DeFalco, Ajit Londhe, Vivienne J. Zhu, Patrick B. Ryan
Feasibility and utility of applications of the common data model to multiple, disparate observational health databases. J. Am. Medical Informatics Assoc. 22 (3) (2015)
George Hripcsak, Jon D. Duke, Nigam H. Shah, Christian G. Reich, Vojtech Huser, Martijn J. Schuemie, Marc A. Suchard, Rae Woong Park, Ian Chi Kei Wong, Peter R. Rijnbeek, Johan van der Lei, Nicole Pratt, G. Niklas Norén, Yu-Chuan Li, Paul E. Stang, David Madigan, Patrick B. Ryan
Observational Health Data Sciences and Informatics (OHDSI): Opportunities for Observational Researchers. MedInfo (2015)
Zhe He, Praveen Chandar Ravichandran, Patrick B. Ryan, Chunhua Weng
Simulation-based Evaluation of the Generalizability Index for Study Traits. AMIA (2015)
Tyler H. McCormick, Rebecca Ferrell, Alan F. Karr, Patrick B. Ryan
Big data, big results: Knowledge discovery in output from large-scale analytics. Stat. Anal. Data Min. 7 (5) (2014)
Vivienne J. Zhu, Rupa Makadia, Amy Matcho, Martijn J. Schuemie, Patrick B. Ryan
Transforming NHANES Database to the OMOP Common Data Model. AMIA (2014)
Vivienne J. Zhu, Patrick B. Ryan, J. Marc Overhage, Paul E. Stang, Jesse Berlin
Developing a Systematic Approach to Measure Medication Adherence. AMIA (2013)
Marc A. Suchard, Shawn E. Simpson, Ivan Zorych, Patrick B. Ryan, David Madigan
Massive Parallelization of Serial Inference Algorithms for a Complex Generalized Linear Model. ACM Trans. Model. Comput. Simul. 23 (1) (2013)
Christian G. Reich, Patrick B. Ryan, Paul E. Stang, Mitra Rocca
Evaluation of alternative standardized terminologies for medical conditions within a network of observational healthcare databases. J. Biomed. Informatics 45 (4) (2012)
J. Marc Overhage, Patrick B. Ryan, Christian G. Reich, Abraham G. Hartzema, Paul E. Stang
Validation of a common data model for active safety surveillance research. J. Am. Medical Informatics Assoc. 19 (1) (2012)
Stephanie J. Reisinger, Patrick B. Ryan, Donald J. O'Hara, Gregory E. Powell, Jeffery L. Painter, Edward N. Pattishall, Jonathan A. Morris
Development and evaluation of a common data model enabling active drug safety surveillance using disparate healthcare databases. J. Am. Medical Informatics Assoc. 17 (6) (2010)