Douglas B. Kell

Publication Activity (10 Years)

Years Active: 1998-2020
Publications (10 Years): 9

Top Topics

Computational Models

Gene Expression

Biomedical Literature

Top Venues

BMC Syst. Biol.

J. Cheminformatics

Publications

Yash Khemchandani, Stephen O'Hagan, Soumitra Samanta, Neil Swainston, Timothy J. Roberts, Danushka Bollegala, Douglas B. Kell
DeepGraphMolGen, a multi-objective, computational strategy for generating molecules with desirable properties: a graph convolution and reinforcement learning approach. J. Cheminformatics 12 (1) (2020)
Pablo Carbonell, Jerry Wong, Neil Swainston, Eriko Takano, Nicholas J. Turner, Nigel S. Scrutton, Douglas B. Kell, Rainer Breitling, Jean-Loup Faulon
Selenzyme: enzyme selection tool for pathway design. Bioinform. 34 (12) (2018)
Neil Swainston, Mark Dunstan, Adrian J. Jervis, Christopher J. Robinson, Pablo Carbonell, Alan R. Williams, Jean-Loup Faulon, Nigel S. Scrutton, Douglas B. Kell
PartsGenie: an integrated tool for optimizing and sharing synthetic biology parts. Bioinform. 34 (13) (2018)
Douglas B. Kell
Evolutionary algorithms and synthetic biology for directed evolution: commentary on "on the mapping of genotype to phenotype in evolutionary algorithms" by Peter A. Whigham, Grant Dick, and James Maclaurin. Genet. Program. Evolvable Mach. 18 (3) (2017)
Andreas Holzinger, Chris Biemann, Constantinos S. Pattichis, Douglas B. Kell
What do we need to build explainable AI systems for the medical domain? CoRR (2017)
Neil Swainston, Andrew Currin, Lucy Green, Rainer Breitling, Philip J. Day, Douglas B. Kell
CodonGenie: optimised ambiguous codon design tools. PeerJ Prepr. 5 (2017)
Steve O'Hagan, Douglas B. Kell
Analysis of drug-endogenous human metabolite similarities in terms of their maximum common substructures. J. Cheminformatics 9 (1) (2017)
Neil Swainston, Andrew Currin, Lucy Green, Rainer Breitling, Philip J. Day, Douglas B. Kell
CodonGenie: optimised ambiguous codon design tools. PeerJ Comput. Sci. 3 (2017)
Andrew Currin, Konstantin Korovin, Maria Ababi, Katherine Roper, Douglas B. Kell, Philip J. Day, Ross D. King
Computing exponentially faster: Implementing a nondeterministic universal Turing machine using DNA. CoRR (2016)
Steve O'Hagan, Douglas B. Kell
Software review: the KNIME workflow environment and its applications in genetic programming and machine learning. Genet. Program. Evolvable Mach. 16 (3) (2015)
Neil Swainston, Andrew Currin, Philip J. Day, Douglas B. Kell
GeneGenie: optimized oligomer design for directed evolution. Nucleic Acids Res. 42 (Webserver-Issue) (2014)
Finja Büchel, Nicolas Rodriguez, Neil Swainston, Clemens Wrzodek, Tobias Czauderna, Roland Keller, Florian Mittag, Michael Schubert, Mihai Glont, Martin Golebiewski, Martijn P. van Iersel, Sarah M. Keating, Matthias Rall, Michael Wybrow, Henning Hermjakob, Michael Hucka, Douglas B. Kell, Wolfgang Müller, Pedro Mendes, Andreas Zell, Claudine Chaouiya, Julio Saez-Rodriguez, Falk Schreiber, Camille Laibe, Andreas Dräger, Nicolas Le Novère
Path2Models: large-scale generation of computational models from biochemical pathway maps. BMC Syst. Biol. 7 (2013)
Makoto Miwa, Tomoko Ohta, Rafal Rak, Andrew Rowley, Douglas B. Kell, Sampo Pyysalo, Sophia Ananiadou
A method for integrating and ranking the evidence for biochemical pathways by mining reactions from text. Bioinform. 29 (13) (2013)
Pinar Pir, Alex Gutteridge, Jian Wu, Bharat Rash, Douglas B. Kell, Nianshu Zhang, Stephen G. Oliver
The genetic control of growth rate: a systems biology study in yeast. BMC Syst. Biol. 6 (2012)
Makoto Miwa, Paul Thompson, John McNaught, Douglas B. Kell, Sophia Ananiadou
Extracting semantically enriched events from biomedical literature. BMC Bioinform. 13 (2012)
Marie Brown, David C. Wedge, Royston Goodacre, Douglas B. Kell, Philip N. Baker, Louise C. Kenny, Mamas A. Mamas, Ludwig Neyses, Warwick B. Dunn
Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets. Bioinform. 28 (1) (2012)
Dave Lee, Kieran Smallbone, Warwick B. Dunn, Ettore Murabito, Catherine Winder, Douglas B. Kell, Pedro Mendes, Neil Swainston
Improving metabolic flux predictions using absolute gene expression data. BMC Syst. Biol. 6 (2012)
Marie Brown, David C. Wedge, Royston Goodacre, Douglas B. Kell, Philip N. Baker, Louise C. Kenny, Mamas A. Mamas, Ludwig Neyses, Warwick B. Dunn
Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets. Bioinform. 27 (8) (2011)
Yogendra Patel, Catherine A. Heyward, Michael R. H. White, Douglas B. Kell
Predicting the points of interaction of small molecules in the NF-κB pathway. BMC Syst. Biol. 5 (2011)
Yunjiao Wang, Pawel Paszek, Caroline A. Horton, Douglas B. Kell, Michael R. H. White, David S. Broomhead, Mark R. Muldoon
Interactions among oscillatory pathways in NF-kappa B signaling. BMC Syst. Biol. 5 (2011)
Neil Swainston, Kieran Smallbone, Pedro Mendes, Douglas B. Kell, Norman W. Paton
The SuBliMinaL Toolbox: automating steps in the reconstruction of metabolic networks. J. Integr. Bioinform. 8 (2) (2011)
Terri K. Attwood, Douglas B. Kell, Philip McDermott, James Marsh, Stephen Pettifer, David Thorne
Utopia documents: linking scholarly literature with research data. Bioinform. 26 (18) (2010)
Paul D. Dobson, Kieran Smallbone, Daniel Jameson, Evangelos Simeonidis, Karin Lanthaler, Pinar Pir, Chuan Lu, Neil Swainston, Warwick B. Dunn, Paul Fisher, Duncan Hull, Marie Brown, Olusegun Oshota, Natalie J. Stanford, Douglas B. Kell, Ross D. King, Stephen G. Oliver, Robert D. Stevens, Pedro Mendes
Further developments towards a genome-scale metabolic model of yeast. BMC Syst. Biol. 4 (2010)
Alice Villéger, Stephen Pettifer, Douglas B. Kell
Arcadia: a visualization tool for metabolic pathways. Bioinform. 26 (11) (2010)
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Spasic, Neil Swainston, Kathleen Carroll, Warwick B. Dunn, Farid Khan, Naglis Malys, Hanan L. Messiha, Evangelos Simeonidis, Dieter Weichart, Catherine Winder, Jill Wishart, David S. Broomhead, Carole A. Goble, Simon J. Gaskell, Douglas B. Kell, Hans V. Westerhoff, Pedro Mendes, Norman W. Paton
Systematic integration of experimental data and models in systems biology. BMC Bioinform. 11 (2010)
William Rowe, David C. Wedge, Mark Platt, Douglas B. Kell, Joshua D. Knowles
Predictive models for population performance on real biological fitness landscapes. Bioinform. 26 (17) (2010)
Daniel Jameson, David A. Turner, John Ankers, Stephnie Kennedy, Sheila Ryan, Neil Swainston, Tony Griffiths, David G. Spiller, Stephen G. Oliver, Michael R. H. White, Douglas B. Kell, Norman W. Paton
Information management for high content live cell imaging. BMC Bioinform. 10 (2009)
Steve Pettifer, David Thorne, Philip McDermott, James Marsh, Alice Villéger, Douglas B. Kell, Teresa K. Attwood
Visualising biological data: a semantic approach to tool and database integration. BMC Bioinform. 10 (S-6) (2009)
Irena Spasic, Evangelos Simeonidis, Hanan L. Messiha, Norman W. Paton, Douglas B. Kell
KiPar, a tool for systematic information retrieval regarding parameters for kinetic modelling of yeast metabolic pathways. Bioinform. 25 (11) (2009)
Thomas Williamson, Jean-Marc Schwartz, Douglas B. Kell, Lubomira Stateva
Deterministic mathematical models of the cAMP pathway in Saccharomyces cerevisiae. BMC Syst. Biol. 3 (2009)
Peter Li, Tom Oinn, Stian Soiland, Douglas B. Kell
Automated manipulation of systems biology models using libSBML within Taverna workflows. Bioinform. 24 (2) (2008)
Peter Li, Juan I. Castrillo, Giles Velarde, Ingo Wassink, Stian Soiland-Reyes, Stuart Owen, David Withers, Tom Oinn, Matthew R. Pocock, Carole A. Goble, Stephen G. Oliver, Douglas B. Kell
Performing statistical analyses on quantitative data in Taverna workflows: An example using R and maxdBrowse to identify differentially-expressed genes from microarray data. BMC Bioinform. 9 (2008)
Caroline Farrelly, Douglas B. Kell, Joshua D. Knowles
Molecular Structure Elucidation Using Ant Colony Optimization: A Preliminary Study. ANTS Conference (2008)
David C. Wedge, Douglas B. Kell
Rapid prediction of optimum population size in genetic programming using a novel genotype -: fitness correlation. GECCO (2008)
Irena Spasic, Daniel Schober, Susanna-Assunta Sansone, Dietrich Rebholz-Schuhmann, Douglas B. Kell, Norman W. Paton
Facilitating the development of controlled vocabularies for metabolomics technologies with text mining. BMC Bioinform. 9 (S-5) (2008)
Duncan Hull, Steve Pettifer, Douglas B. Kell
Defrosting the Digital Library: Bibliographic Tools for the Next Generation Web. PLoS Comput. Biol. 4 (10) (2008)
Yisu Jin, Joshua D. Knowles, Hongmei Lu, Yizeng Liang, Douglas B. Kell
The landscape adaptive particle swarm optimizer. Appl. Soft Comput. 8 (1) (2008)
Bayu Jayawardhana, Douglas B. Kell, Magnus Rattray
Bayesian inference of the sites of perturbations in metabolic pathways via Markov chain Monte Carlo. Bioinform. 24 (9) (2008)
Thomas Williamson, Frank Bruggemann, Douglas B. Kell, Lubomira Stateva
Towards a mathematical model of the cAMP pathway in S. cerevisiae. BMC Syst. Biol. 1 (S-1) (2007)
Yisu Jin, Hong Yue, Martin Brown, Yizeng Liang, Douglas B. Kell
Improving Data Fitting of a Signal Transduction Model by Global Sensitivity Analysis. ACC (2007)
David C. Wedge, Simon J. Gaskell, Simon J. Hubbard, Douglas B. Kell, King Wai Lau, Claire Eyers
Peptide detectability following ESI mass spectrometry: prediction using genetic programming. GECCO (2007)
Julia Handl, Douglas B. Kell, Joshua D. Knowles
Multiobjective Optimization in Bioinformatics and Computational Biology. IEEE ACM Trans. Comput. Biol. Bioinform. 4 (2) (2007)
Irena Spasic, Warwick B. Dunn, Giles Velarde, Andy Tseng, Helen Jenkins, Nigel Hardy, Stephen G. Oliver, Douglas B. Kell
MeMo: a hybrid SQL/XML approach to metabolomic data management for functional genomics. BMC Bioinform. 7 (2006)
Julia Handl, Joshua D. Knowles, Douglas B. Kell
Computational cluster validation in post-genomic data analysis. Bioinform. 21 (15) (2005)
David Hancock, Michael Wilson, Giles Velarde, Norman Morrison, Andrew Hayes, Helen Hulme, A. Joseph Wood, Karim Nashar, Douglas B. Kell, Andy Brass
maxdLoad2 and maxdBrowse: standards-compliant tools for microarray experimental annotation, data management and dissemination. BMC Bioinform. 6 (2005)
David Corne, Martin J. Oates, Douglas B. Kell
Landscape State Machines: Tools for Evolutionary Algorithm Performance Analyses and Landscape/Algorithm Mapping. EvoWorkshops (2003)
David W. Corne, Martin J. Oates, Douglas B. Kell
Fitness Gains and Mutation Patterns: Deriving Mutation Rates by Exploiting Landscape Data. FOGA (2002)
David Corne, Martin J. Oates, Douglas B. Kell
On Fitness Distributions and Expected Fitness Gain of Mutation Rates in Parallel Evolutionary Algorithms. PPSN (2002)
Martin J. Oates, David Corne, Douglas B. Kell
Observed dynamics of Large Scale Parallel Evolutionary Algorithms with Implications for protein Engineering. SEAL (2002)
Philip G. K. Reiser, Ross D. King, Douglas B. Kell, Stephen Muggleton, Christopher H. Bryant, Stephen G. Oliver
Developing a Logical Model of Yeast Metabolism. Electron. Trans. Artif. Intell. 5 (B) (2001)
Pedro Mendes, Douglas B. Kell
MEG (Model Extender for Gepasi): a program for the modelling of complex, heterogeneous, cellular systems. Bioinform. 17 (3) (2001)
Wei Liu, Andy Woodward, Douglas B. Kell
Compression of proteome gel images using complex wavelet transform. German Conference on Bioinformatics (2001)
Janet Taylor, Jem J. Rowland, Douglas B. Kell
Spectral analysis via supervised genetic search with application-specific mutations. CEC (2001)
Christopher H. Bryant, Stephen Muggleton, Stephen G. Oliver, Douglas B. Kell, Philip G. K. Reiser, Ross D. King
Combining Inductive Logic Programming, Active Learning and Robotics to Discover the Function of Genes. Electron. Trans. Artif. Intell. 5 (B) (2001)
Helen E. Johnson, Richard J. Gilbert, Michael K. Winson, Royston Goodacre, Aileen R. Smith, Jem J. Rowland, Michael A. Hall, Douglas B. Kell
Explanatory Analysis of the Metabolome Using Genetic Programming of Simple, Interpretable Rules. Genet. Program. Evolvable Mach. 1 (3) (2000)
Richard J. Gilbert, Jem J. Rowland, Douglas B. Kell
Genomic computing: explanatory modelling for functional genomics. GECCO (2000)
Pedro Mendes, Douglas B. Kell
Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation. Bioinform. 14 (10) (1998)