David N. Cooper

Publication Activity (10 Years)

Years Active: 1998-2023
Publications (10 Years): 11

Top Topics

Genotype Phenotype

Top Venues

Nucleic Acids Res.

PLoS Comput. Biol.

Publications

Siying Lin, Haoyang Zhang, Mengling Qi, David N. Cooper, Yuedong Yang, Yuanhao Yang, Huiying Zhao
Inferring the genetic relationship between brain imaging-derived phenotypes and risk of complex diseases by Mendelian randomization and genome-wide colocalization. NeuroImage 279 (2023)
Robin Steinhaus, Sebastian Proft, Markus Schuelke, David N. Cooper, Jana Marie Schwarz, Dominik Seelow
MutationTaster2021. Nucleic Acids Res. 49 (Webserver-Issue) (2021)
Peng Zhang, Bertrand Boisson, Peter D. Stenson, David N. Cooper, Jean-Laurent Casanova, Laurent Abel, Yuval Itan
SeqTailor: a user-friendly webserver for the extraction of DNA or protein sequences from next-generation sequencing data. Nucleic Acids Res. 47 (Webserver-Issue) (2019)
Kymberleigh A. Pagel, Danny Antaki, Aojie Lian, Matthew E. Mort, David N. Cooper, Jonathan Sebat, Lilia M. Iakoucheva, Sean D. Mooney, Predrag Radivojac
Pathogenicity and functional impact of non-frameshifting insertion/deletion variation in the human genome. PLoS Comput. Biol. 15 (6) (2019)
Jana Marie Schwarz, Daniela Hombach, Sebastian Köhler, David N. Cooper, Markus Schuelke, Dominik Seelow
RegulationSpotter: annotation and interpretation of extratranscriptic DNA variants. Nucleic Acids Res. 47 (Webserver-Issue) (2019)
Mark F. Rogers, Hashem A. Shihab, Matthew E. Mort, David N. Cooper, Tom R. Gaunt, Colin Campbell
FATHMM-XF: accurate prediction of pathogenic point mutations via extended features. Bioinform. 34 (3) (2018)
Igor B. Rogozin, Youri I. Pavlov, Alexander Goncearenco, Subhajyoti De, Artem G. Lada, Eugenia Poliakov, Anna R. Panchenko, David N. Cooper
Mutational signatures and mutable motifs in cancer genomes. Briefings Bioinform. 19 (6) (2018)
Kymberleigh A. Pagel, Vikas Pejaver, Guan Ning Lin, Hyun-Jun Nam, Matthew E. Mort, David N. Cooper, Jonathan Sebat, Lilia M. Iakoucheva, Sean D. Mooney, Predrag Radivojac
When loss-of-function is loss of function: assessing mutational signatures and impact of loss-of-function genetic variants. Bioinform. 33 (14) (2017)
Michael Ferlaino, Mark F. Rogers, Hashem A. Shihab, Matthew E. Mort, David N. Cooper, Tom R. Gaunt, Colin Campbell
An integrative approach to predicting the functional effects of small indels in non-coding regions of the human genome. BMC Bioinform. 18 (1) (2017)
Sérgio Matos, David Campos, Renato P. Pinho, Raquel M. Silva, Matthew E. Mort, David N. Cooper, José Luís Oliveira
Mining clinical attributes of genomic variants through assisted literature curation in Egas. Database J. Biol. Databases Curation 2016 (2016)
Jose Lugo-Martinez, Vikas Pejaver, Kymberleigh A. Pagel, Shantanu Jain, Matthew E. Mort, David N. Cooper, Sean D. Mooney, Predrag Radivojac
The Loss and Gain of Functional Amino Acid Residues Is a Common Mechanism Causing Human Inherited Disease. PLoS Comput. Biol. 12 (8) (2016)
Hashem A. Shihab, Mark F. Rogers, Julian Gough, Matthew E. Mort, David N. Cooper, Ian N. M. Day, Tom R. Gaunt, Colin Campbell
An integrative approach to predicting the functional effects of non-coding and coding sequence variation. Bioinform. 31 (10) (2015)
Lukas Folkman, Yuedong Yang, Zhixiu Li, Bela Stantic, Abdul Sattar, Matthew E. Mort, David N. Cooper, Yunlong Liu, Yaoqi Zhou
DDIG-in: detecting disease-causing genetic variations due to frameshifting indels and nonsense mutations employing sequence and structural properties at nucleotide and protein levels. Bioinform. 31 (10) (2015)
Mark F. Rogers, Colin Campbell, Hashem A. Shihab, Tom R. Gaunt, Matthew E. Mort, David N. Cooper
Sequential data selection for predicting the pathogenic effects of sequence variation. BIBM (2015)
Yun-Ching Chen, Christopher Douville, Cheng Wang, Noushin Niknafs, Grace Yeo, Violeta Beleva Guthrie, Hannah Carter, Peter D. Stenson, David N. Cooper, Biao Li, Sean D. Mooney, Rachel Karchin
A Probabilistic Model to Predict Clinical Phenotypic Traits from Genome Sequencing. PLoS Comput. Biol. 10 (9) (2014)
Christopher Douville, Hannah Carter, Rick Kim, Noushin Niknafs, Mark Diekhans, Peter D. Stenson, David N. Cooper, Michael C. Ryan, Rachel Karchin
CRAVAT: cancer-related analysis of variants toolkit. Bioinform. 29 (5) (2013)
Hashem A. Shihab, Julian Gough, David N. Cooper, Ian N. M. Day, Tom R. Gaunt
Predicting the functional consequences of cancer-associated amino acid substitutions. Bioinform. 29 (12) (2013)
Mingxiang Teng, Shoji Ichikawa, Leah R. Padgett, Yadong Wang, Matthew E. Mort, David N. Cooper, Daniel L. Koller, Tatiana Foroud, Howard J. Edenberg, Michael J. Econs, Yunlong Liu
regSNPs: a strategy for prioritizing regulatory single nucleotide substitutions. Bioinform. 28 (14) (2012)
Fuxiao Xin, Steven A. Myers, Yong Fuga Li, David N. Cooper, Sean D. Mooney, Predrag Radivojac
Structure-based kernels for the prediction of catalytic residues and their involvement in human inherited disease. Bioinform. 26 (16) (2010)
Fuxiao Xin, Steven A. Myers, Yong Fuga Li, David N. Cooper, Sean D. Mooney, Predrag Radivojac
Structure-based kernels for the prediction of catalytic residues and their involvement in human inherited disease. BMC Bioinform. 11 (S-10) (2010)
Biao Li, Vidhya G. Krishnan, Matthew E. Mort, Fuxiao Xin, Kishore K. Kamati, David N. Cooper, Sean D. Mooney, Predrag Radivojac
Automated inference of molecular mechanisms of disease from amino acid substitutions. Bioinform. 25 (21) (2009)
Imtiaz A. Khan, Matthew E. Mort, Paul R. Buckland, Michael C. O'Donovan, David N. Cooper, Nadia A. Chuzhanova
In Silico Discrimination of Single Nucleotide Polymorphisms and Pathological Mutations in Human Gene Promoter Regions by Means of Local DNA Sequence Context and Regularity. Silico Biol. 6 (1-2) (2006)
David N. Cooper, Edward V. Ball, Michael Krawczak
The human gene mutation database. Nucleic Acids Res. 26 (1) (1998)