Mutational signatures and mutable motifs in cancer genomes.
Igor B. RogozinYouri I. PavlovAlexander GoncearencoSubhajyoti DeArtem G. LadaEugenia PoliakovAnna R. PanchenkoDavid N. CooperPublished in: Briefings Bioinform. (2018)
Keyphrases
- genome sequences
- dna sequences
- human genome
- sequence data
- genomic data
- protein families
- breast cancer
- outcome prediction
- binding sites
- comparative analysis
- biological sequences
- regulatory elements
- phylogenetic analysis
- motif discovery
- signature recognition
- protein sequences
- motif finding
- sequence analysis
- early detection
- signature verification
- genome annotation
- cancer diagnosis
- colorectal cancer
- prostate cancer
- network motifs
- rna sequences
- phylogenetic trees
- cancer cells
- gene expression profiles
- genomic sequences
- copy number
- transcription factors
- cancer patients
- tissue samples
- repeated patterns
- signature scheme
- gene selection