Aik Choon Tan

Publication Activity (10 Years)

Years Active: 2003-2024
Publications (10 Years): 15

Top Topics

Molecular Mechanisms

Medline Abstracts

Top Venues

PLoS Comput. Biol.

Database J. Biol. Databases Curation

Publications

Xiang Liu, Nancy Gillis, Chang Jiang, Anthony McCofie, Timothy I. Shaw, Aik Choon Tan, Bo Zhao, Lixin Wan, Derek R. Duckett, Mingxiang Teng
An Epigenomic fingerprint of human cancers by landscape interrogation of super enhancers at the constituent level. PLoS Comput. Biol. 20 (2) (2024)
Ramin Homayouni, Prashanti Manda, Aik Choon Tan, Zhaohui S. Qin
Editorial: AI and data science in drug development and public health: Highlights from the MCBIOS 2022 conference. Frontiers Big Data 6 (2023)
Ching-Nung Lin, Christine H. Chung, Aik Choon Tan
NuKit: A deep learning platform for fast nucleus segmentation of histopathological images. J. Bioinform. Comput. Biol. 21 (1) (2023)
Alyssa N. Obermayer, Darwin Chang, Gabrielle Nobles, Mingxiang Teng, Aik Choon Tan, Xuefeng Wang, Y. Ann Chen, Steven Eschrich, Paulo C. Rodriguez, G. Daniel Grass, Soheil Meshinchi, Ahmad Tarhini, Dung-tsa Chen, Timothy I. Shaw
PATH-SURVEYOR: pathway level survival enquiry for immuno-oncology and drug repurposing. BMC Bioinform. 24 (1) (2023)
Zhaoping Xiong, Minji Jeon, Robert J. Allaway, Jaewoo Kang, Donghyeon Park, Jinhyuk Lee, Hwisang Jeon, Miyoung Ko, Hualiang Jiang, Mingyue Zheng, Aik Choon Tan, Xindi Guo, Multi-Targeting Drug DREAM Challenge Community, Kristen K. Dang, Alex Tropsha, Chana Hecht, Tirtha K. Das, Heather A. Carlson, Ruben Abagyan, Justin Guinney, Avner Schlessinger, Ross Cagan
Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge. PLoS Comput. Biol. 17 (9) (2021)
Mengyu Xie, Kyubum Lee, John H. Lockhart, Scott D. Cukras, Rodrigo Carvajal, Amer A. Beg, Elsa R. Flores, Mingxiang Teng, Christine H. Chung, Aik Choon Tan
TIMEx: tumor-immune microenvironment deconvolution web-portal for bulk transcriptomics using pan-cancer scRNA-seq signatures. Bioinform. 37 (20) (2021)
Kyubum Lee, John H. Lockhart, Mengyu Xie, Ritu Chaudhary, Robbert J. C. Slebos, Elsa R. Flores, Christine H. Chung, Aik Choon Tan
Deep Learning of Histopathology Images at the Single Cell Level. Frontiers Artif. Intell. 4 (2021)
Minji Jeon, Donghyeon Park, Jinhyuk Lee, Hwisang Jeon, Miyoung Ko, Sunkyu Kim, Yonghwa Choi, Aik Choon Tan, Jaewoo Kang
ReSimNet: drug response similarity prediction using Siamese neural networks. Bioinform. 35 (24) (2019)
Minjae Yoo, Jimin Shin, Hyunmin Kim, Jihye Kim, Jaewoo Kang, Aik Choon Tan
Exploring the molecular mechanisms of Traditional Chinese Medicine components using gene expression signatures and connectivity map. Comput. Methods Programs Biomed. 174 (2019)
Rani K. Powers, Andrew Goodspeed, Harrison Pielke-Lombardo, Aik Choon Tan, James C. Costello
GSEA-InContext: identifying novel and common patterns in expression experiments. Bioinform. 34 (13) (2018)
Zongliang Yue, Qi Zheng, Michael T. Neylon, Minjae Yoo, Jimin Shin, Zhiying Zhao, Aik Choon Tan, Jake Y. Chen
PAGER 2.0: an update to the pathway, annotated-list and gene-signature electronic repository for Human Network Biology. Nucleic Acids Res. 46 (Database-Issue) (2018)
Kyubum Lee, Byounggun Kim, Yonghwa Choi, Sunkyu Kim, Won-Ho Shin, Sunwon Lee, Sungjoon Park, Seongsoon Kim, Aik Choon Tan, Jaewoo Kang
Deep learning of mutation-gene-drug relations from the literature. BMC Bioinform. 19 (1) (2018)
Jennifer Hintzsche, Jihye Kim, Vinod Kumar Yadav, Carol Amato, Steven E. Robinson, Eric Seelenfreund, Yiqun Shellman, Joshua Wisell, Allison Applegate, Martin McCarter, Neil Box, John Tentler, Subhajyoti De, William A. Robinson, Aik Choon Tan
IMPACT: a whole-exome sequencing analysis pipeline for integrating molecular profiles with actionable therapeutics in clinical samples. J. Am. Medical Informatics Assoc. 23 (4) (2016)
Kyubum Lee, Won-Ho Shin, Byounggun Kim, Sunwon Lee, Yonghwa Choi, Sunkyu Kim, Minji Jeon, Aik Choon Tan, Jaewoo Kang
HiPub: translating PubMed and PMC texts to networks for knowledge discovery. Bioinform. 32 (18) (2016)
Kyubum Lee, Sunwon Lee, Sungjoon Park, Sunkyu Kim, Suhkyung Kim, Kwanghun Choi, Aik Choon Tan, Jaewoo Kang
BRONCO: Biomedical entity Relation ONcology COrpus for extracting gene-variant-disease-drug relations. Database J. Biol. Databases Curation 2016 (2016)
Karen A. Ryall, Jimin Shin, Minjae Yoo, Trista K. Hinz, Jihye Kim, Jaewoo Kang, Lynn E. Heasley, Aik Choon Tan
Identifying kinase dependency in cancer cells by integrating high-throughput drug screening and kinase inhibition data. Bioinform. 31 (23) (2015)
Karen A. Ryall, Aik Choon Tan
Systems biology approaches for advancing the discovery of effective drug combinations. J. Cheminformatics 7 (2015)
Minjae Yoo, Jimin Shin, Jihye Kim, Karen A. Ryall, Kyubum Lee, Sunwon Lee, Minji Jeon, Jaewoo Kang, Aik Choon Tan
DSigDB: drug signatures database for gene set analysis. Bioinform. 31 (18) (2015)
Jihye Kim, Vihas T. Vasu, Rangnath Mishra, Katherine R. Singleton, Minjae Yoo, Sonia M. Leach, Eveline Farias-Hesson, Robert J. Mason, Jaewoo Kang, Preveen Ramamoorthy, Jeffrey A. Kern, Lynn E. Heasley, James H. Finigan, Aik Choon Tan
Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy. Bioinform. 30 (17) (2014)
Minji Jeon, Sunwon Lee, Kyubum Lee, Aik Choon Tan, Jaewoo Kang
BEReX: Biomedical Entity-Relationship eXplorer. Bioinform. 30 (1) (2014)
Donald Geman, Bahman Afsari, Aik Choon Tan, Daniel Q. Naiman
Microarray Classification from Several Two-Gene Expression Comparisons. ICMLA (2008)
Lei Xu, Aik Choon Tan, Raimond L. Winslow, Donald Geman
Merging microarray data from separate breast cancer studies provides a robust prognostic test. BMC Bioinform. 9 (2008)
Aik Choon Tan, Daniel Q. Naiman, Lei Xu, Raimond L. Winslow, Donald Geman
Simple decision rules for classifying human cancers from gene expression profiles. Bioinform. 21 (20) (2005)
Lei Xu, Aik Choon Tan, Daniel Q. Naiman, Donald Geman, Raimond L. Winslow
Robust prostate cancer marker genes emerge from direct integration of inter-study microarray data. Bioinform. 21 (20) (2005)
Ali Al-Shahib, Chao He, Aik Choon Tan, Mark A. Girolami, David R. Gilbert
An Assessment of Feature Relevance in Predicting Protein Function from Sequence. IDEAL (2004)
Aik Choon Tan, David R. Gilbert
An Empirical Comparison of Supervised Machine Learning Techniques in Bioinformatics. APBC (2003)
Aik Choon Tan, David R. Gilbert, Yves Deville
Integrative machine learning approach for multi-class SCOP protein fold classification. German Conference on Bioinformatics (2003)