Peichen Pan

Publication Activity (10 Years)

Years Active: 1992-2024
Publications (10 Years): 18

Top Topics

Geometric Structure

Convolutional Neural Networks

Virtual Screening

Top Venues

J. Cheminformatics

J. Chem. Inf. Model.

Comput. Biol. Medicine

Publications

Tianhao Wang, Jianbo Tong, Xing Zhang, Zhe Wang, Lei Xu, Peichen Pan, Tingjun Hou
Structure-based virtual screening of novel USP5 inhibitors targeting the zinc finger ubiquitin-binding domain. Comput. Biol. Medicine 174 (2024)
Odin Zhang, Haitao Lin, Hui Zhang, Huifeng Zhao, Yufei Huang, Yuansheng Huang, Dejun Jiang, Chang-Yu Hsieh, Peichen Pan, Tingjun Hou
Deep Lead Optimization: Leveraging Generative AI for Structural Modification. CoRR (2024)
Mingyang Wang, Zhengjian Wu, Jike Wang, Gaoqi Weng, Yu Kang, Peichen Pan, Dan Li, Yafeng Deng, Xiaojun Yao, Zhitong Bing, Chang-Yu Hsieh, Tingjun Hou
Genetic Algorithm-Based Receptor Ligand: A Genetic Algorithm-Guided Generative Model to Boost the Novelty and Drug-Likeness of Molecules in a Sampling Chemical Space. J. Chem. Inf. Model. 64 (4) (2024)
Xing Zhang, Jianbo Tong, Tianhao Wang, Tianyue Wang, Lei Xu, Zhe Wang, Tingjun Hou, Peichen Pan
Dissecting the role of ALK double mutations in drug resistance to lorlatinib with in-depth theoretical modeling and analysis. Comput. Biol. Medicine 169 (2024)
Wenjia Qian, Xiaorui Wang, Yu Kang, Peichen Pan, Tingjun Hou, Chang-Yu Hsieh
A general model for predicting enzyme functions based on enzymatic reactions. J. Cheminformatics 16 (1) (2024)
Odin Zhang, Yufei Huang, Shichen Cheng, Mengyao Yu, Xujun Zhang, Haitao Lin, Yundian Zeng, Mingyang Wang, Zhenxing Wu, Huifeng Zhao, Zaixi Zhang, Chenqing Hua, Yu Kang, Sunliang Cui, Peichen Pan, Chang-Yu Hsieh, Tingjun Hou
Deep Geometry Handling and Fragment-wise Molecular 3D Graph Generation. CoRR (2024)
Odin Zhang, Tianyue Wang, Gaoqi Weng, Dejun Jiang, Ning Wang, Xiaorui Wang, Huifeng Zhao, Jialu Wu, Ercheng Wang, Guangyong Chen, Yafeng Deng, Peichen Pan, Yu Kang, Chang-Yu Hsieh, Tingjun Hou
Learning on topological surface and geometric structure for 3D molecular generation. Nat. Comput. Sci. 3 (10) (2023)
Xujun Zhang, Chao Shen, Tianyue Wang, Yafeng Deng, Yu Kang, Dan Li, Tingjun Hou, Peichen Pan
ML-PLIC: a web platform for characterizing protein-ligand interactions and developing machine learning-based scoring functions. Briefings Bioinform. 24 (5) (2023)
Zhe Wang, Haiyang Zhong, Jintu Zhang, Peichen Pan, Dong Wang, Huanxiang Liu, Xiaojun Yao, Tingjun Hou, Yu Kang
Small-Molecule Conformer Generators: Evaluation of Traditional Methods and AI Models on High-Quality Data Sets. J. Chem. Inf. Model. 63 (21) (2023)
Xujun Zhang, Chao Shen, Dejun Jiang, Jintu Zhang, Qing Ye, Lei Xu, Tingjun Hou, Peichen Pan, Yu Kang
TB-IECS: an accurate machine learning-based scoring function for virtual screening. J. Cheminformatics 15 (1) (2023)
Xujun Zhang, Odin Zhang, Chao Shen, Wanglin Qu, Shicheng Chen, Hanqun Cao, Yu Kang, Zhe Wang, Ercheng Wang, Jintu Zhang, Yafeng Deng, Furui Liu, Tianyue Wang, Hongyan Du, Langcheng Wang, Peichen Pan, Guangyong Chen, Chang-Yu Hsieh, Tingjun Hou
Efficient and accurate large library ligand docking with KarmaDock. Nat. Comput. Sci. 3 (9) (2023)
Mingyang Wang, Jike Wang, Gaoqi Weng, Yu Kang, Peichen Pan, Dan Li, Yafeng Deng, Honglin Li, Chang-Yu Hsieh, Tingjun Hou
ReMODE: a deep learning-based web server for target-specific drug design. J. Cheminformatics 14 (1) (2022)
Gaoang Wang, Jiahui Yu, Hongyan Du, Chao Shen, Xujun Zhang, Yifei Liu, Yangyang Zhang, Dong-Sheng Cao, Peichen Pan, Tingjun Hou
VGSC-DB: an online database of voltage-gated sodium channels. J. Cheminformatics 14 (1) (2022)
Jason Cong, Jason Lau, Gai Liu, Stephen Neuendorffer, Peichen Pan, Kees A. Vissers, Zhiru Zhang
FPGA HLS Today: Successes, Challenges, and Opportunities. ACM Trans. Reconfigurable Technol. Syst. 15 (4) (2022)
Chen Zhang, Guangyu Sun, Zhenman Fang, Peipei Zhou, Peichen Pan, Jason Cong
Caffeine: Toward Uniformed Representation and Acceleration for Deep Convolutional Neural Networks. IEEE Trans. Comput. Aided Des. Integr. Circuits Syst. 38 (11) (2019)
Jun Shang, Huiyong Sun, Hui Liu, Fu Chen, Sheng Tian, Peichen Pan, Dan Li, De-Xin Kong, Tingjun Hou
Comparative analyses of structural features and scaffold diversity for purchasable compound libraries. J. Cheminformatics 9 (1) (2017)
Jason Cong, Muhuan Huang, Peichen Pan, Di Wu, Peng Zhang
Software Infrastructure for Enabling FPGA-Based Accelerations in Data Centers: Invited Paper. ISLPED (2016)
Chen Zhang, Zhenman Fang, Peipei Zhou, Peichen Pan, Jason Cong
Caffeine: towards uniformed representation and acceleration for deep convolutional neural networks. ICCAD (2016)
Peichen Pan, Sheng Tian, Huiyong Sun, Xiaotian Kong, Wenfang Zhou, Dan Li, Youyong Li, Tingjun Hou
Identification and Preliminary SAR Analysis of Novel Type-I Inhibitors of TIE-2 via Structure-Based Virtual Screening and Biological Evaluation in in vitro Models. J. Chem. Inf. Model. 55 (12) (2015)
Sheng Tian, Huiyong Sun, Peichen Pan, Dan Li, Xuechu Zhen, Youyong Li, Tingjun Hou
Assessing an Ensemble Docking-Based Virtual Screening Strategy for Kinase Targets by Considering Protein Flexibility. J. Chem. Inf. Model. 54 (10) (2014)
Peichen Pan, Youyong Li, Huidong Yu, Huiyong Sun, Tingjun Hou
Molecular Principle of Topotecan Resistance by Topoisomerase I Mutations through Molecular Modeling Approaches. J. Chem. Inf. Model. 53 (4) (2013)
Sheng Tian, Huiyong Sun, Youyong Li, Peichen Pan, Dan Li, Tingjun Hou
Development and Evaluation of an Integrated Virtual Screening Strategy by Combining Molecular Docking and Pharmacophore Searching Based on Multiple Protein Structures. J. Chem. Inf. Model. 53 (10) (2013)
Deming Chen, Jason Cong, Peichen Pan
FPGA Design Automation: A Survey. Found. Trends Electron. Des. Autom. 1 (3) (2006)
Parthasarathi Dasgupta, Peichen Pan, Subhas C. Nandy, Bhargab B. Bhattacharya
Monotone bipartitioning problem in a planar point set with applications to VLSI. ACM Trans. Design Autom. Electr. Syst. 7 (2) (2002)
Peichen Pan, Guohua Chen
Optimal Retiming for Initial State Computation. VLSI Design (1999)
Peichen Pan
Performance-Driven Integration of Retiming and Resynthesis. DAC (1999)
Prashant Saxena, Peichen Pan, C. L. Liu
The Retiming of Single-Phase Clocked Circuits Containing Level-Sensitive Latches. VLSI Design (1999)
Peichen Pan, C. L. Liu
Partial Scan with Preselected Scan Signals. IEEE Trans. Computers 48 (9) (1999)
Peichen Pan, Arvind K. Karandikar, C. L. Liu
Optimal clock period clustering for sequential circuits with retiming. IEEE Trans. Comput. Aided Des. Integr. Circuits Syst. 17 (6) (1998)
Unni Narayanan, Peichen Pan, C. L. Liu
Low power logic synthesis under a general delay model. ISLPED (1998)
Peichen Pan, C. L. Liu
Optimal clock period FPGA technology mapping for sequential circuits. ACM Trans. Design Autom. Electr. Syst. 3 (3) (1998)
Peichen Pan, Chih-Chang Lin
A New Retiming-Based Technology Mapping Algorithm for LUT-based FPGAs. FPGA (1998)
Arvind K. Karandikar, Peichen Pan, C. L. Liu
Optimal Clock Period Clustering for Sequential Circuits with Retiming. ICCD (1997)
Peichen Pan, Sai-keung Dong, C. L. Liu
Optimal Graph Constraint Reduction for Symbolic Layout Compaction. Algorithmica 18 (4) (1997)
Peichen Pan
Continuous Retiming: Algorithms and Applications. ICCD (1997)
Peichen Pan, Weiping Shi, C. L. Liu
Area Minimization for Hierarchical Floorplans. Algorithmica 15 (6) (1996)
Peichen Pan, C. L. Liu
Optimal Clock Period FPGA Technology Mapping for Sequential Circuits. DAC (1996)
Peichen Pan, C. L. Liu
Technology Mapping of Sequential Circuits for LUT-Based FPGAs for Performance. FPGA (1996)
Xiangfeng Chen, Peichen Pan, C. L. Liu
Desensitization for Power Reduction in Sequential Circuits. DAC (1996)
Peichen Pan, C. L. Liu
Area minimization for floorplans. IEEE Trans. Comput. Aided Des. Integr. Circuits Syst. 14 (1) (1995)
Peichen Pan, C. L. Liu
Partial Scan with Pre-selected Scan Signals. DAC (1995)
Peichen Pan, Weiping Shi, C. L. Liu
Area minimization for hierarchical floorplans. ICCAD (1994)
Peichen Pan, Sai-keung Dong, C. L. Liu
Optimal Graph Constraint Reduction for Symbolic Layout Compaction. DAC (1993)
Peichen Pan, C. L. Liu
Area minimization for general floorplans. ICCAD (1992)