Desmond G. Higgins

Publication Activity (10 Years)

Years Active: 1987-2020
Publications (10 Years): 4

Top Topics

Protein Sequences

Multiple Sequence Alignments

Secondary Structure

Top Venues

Nucleic Acids Res.

Algorithms Mol. Biol.

Publications

Fabian Sievers, Desmond G. Higgins
QuanTest2: benchmarking multiple sequence alignments using secondary structure prediction. Bioinform. 36 (1) (2020)
Quan Le, Fabian Sievers, Desmond G. Higgins
Protein multiple sequence alignment benchmarking through secondary structure prediction. Bioinform. 33 (9) (2017)
Peter Jehl, Jean Manguy, Denis C. Shields, Desmond G. Higgins, Norman E. Davey
ProViz - a web-based visualization tool to investigate the functional and evolutionary features of protein sequences. Nucleic Acids Res. 44 (Webserver-Issue) (2016)
Gearoid Fox, Fabian Sievers, Desmond G. Higgins
protein structure predictions to measure the quality of very large multiple sequence alignments. Bioinform. 32 (6) (2016)
Kieran Boyce, Fabian Sievers, Desmond G. Higgins
Instability in progressive multiple sequence alignment algorithms. Algorithms Mol. Biol. 10 (2015)
Peter Jehl, Fabian Sievers, Desmond G. Higgins
OD-seq: outlier detection in multiple sequence alignments. BMC Bioinform. 16 (2015)
Audrey M. Michel, Gearoid Fox, Anmol M. Kiran, Christof De Bo, Patrick B. F. O'Connor, Stephen M. Heaphy, James P. A. Mullan, Claire A. Donohue, Desmond G. Higgins, Pavel V. Baranov
GWIPS-viz: development of a ribo-seq genome browser. Nucleic Acids Res. 42 (Database-Issue) (2014)
Fabian Sievers, Graham M. Hughes, Desmond G. Higgins
Systematic exploration of guide-tree topology effects for small protein alignments. BMC Bioinform. 15 (2014)
Fabian Sievers, David Dineen, Andreas Wilm, Desmond G. Higgins
Making automated multiple alignments of very large numbers of protein sequences. Bioinform. 29 (8) (2013)
Stephen F. Madden, Susan B. Carpenter, Ian B. Jeffery, Harry Björkbacka, Katherine A. Fitzgerald, Luke A. O'Neill, Desmond G. Higgins
Detecting microRNA activity from gene expression data. BMC Bioinform. 11 (2010)
Gordon Blackshields, Fabian Sievers, Weifeng Shi, Andreas Wilm, Desmond G. Higgins
Sequence embedding for fast construction of guide trees for multiple sequence alignment. Algorithms Mol. Biol. 5 (2010)
Sébastien Moretti, Andreas Wilm, Desmond G. Higgins, Ioannis Xenarios, Cédric Notredame
R-Coffee: a web server for accurately aligning noncoding RNA sequences. Nucleic Acids Res. 36 (Web-Server-Issue) (2008)
Simon J. Furney, Stephen F. Madden, Tomasz A. Kisiel, Desmond G. Higgins, Núria López-Bigas
Distinct Patterns in the Regulation and Evolution of Human Cancer Genes. Silico Biol. 8 (1) (2008)
Gordon Blackshields, Mark A. Larkin, Iain M. Wallace, Andreas Wilm, Desmond G. Higgins
Fast embedding methods for clustering tens of thousands of sequences. Comput. Biol. Chem. 32 (4) (2008)
Sébastien Moretti, Fabrice Armougom, Iain M. Wallace, Desmond G. Higgins, C. Victor Jongeneel, Cédric Notredame
The M-Coffee web server: a meta-method for computing multiple sequence alignments by combining alternative alignment methods. Nucleic Acids Res. 35 (Web-Server-Issue) (2007)
Ian B. Jeffery, Stephen F. Madden, Paul A. McGettigan, Guy Perrière, Aedín C. Culhane, Desmond G. Higgins
Integrating transcription factor binding site information with gene expression datasets. Bioinform. 23 (3) (2007)
Iain M. Wallace, Desmond G. Higgins
Supervised multivariate analysis of sequence groups to identify specificity determining residues. BMC Bioinform. 8 (2007)
Mark A. Larkin, Gordon Blackshields, N. P. Brown, R. Chenna, Paul A. McGettigan, Hamish McWilliam, Franck Valentin, Iain M. Wallace, Andreas Wilm, Rodrigo Lopez, Julie Dawn Thompson, Toby J. Gibson, Desmond G. Higgins
Clustal W and Clustal X version 2.0. Bioinform. 23 (21) (2007)
Gordon Blackshields, Iain M. Wallace, Mark A. Larkin, Desmond G. Higgins
Analysis and Comparison of Benchmarks for Multiple Sequence Alignment. Silico Biol. 6 (4) (2006)
Ian B. Jeffery, Desmond G. Higgins, Aedín C. Culhane
Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data. BMC Bioinform. 7 (2006)
Fabrice Armougom, Olivier Poirot, Sébastien Moretti, Desmond G. Higgins, Phillip Bucher, Vladimir Keduas, Cédric Notredame
APDB: a web server to evaluate the accuracy of sequence alignments using structural information. Bioinform. 22 (19) (2006)
Iain M. Wallace, Orla O'Sullivan, Desmond G. Higgins
Evaluation of iterative alignment algorithms for multiple alignment. Bioinform. 21 (8) (2005)
Aedín C. Culhane, Jean Thioulouse, Guy Perrière, Desmond G. Higgins
MADE4: an R package for multivariate analysis of gene expression data. Bioinform. 21 (11) (2005)
Chenna Ramu, Hideaki Sugawara, Tadashi Koike, Rodrigo Lopez, Toby J. Gibson, Desmond G. Higgins, Julie Dawn Thompson
Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res. 31 (13) (2003)
Orla O'Sullivan, Mark Zehnder, Desmond G. Higgins, Philipp Bucher, Aurélien Grosdidier, Cédric Notredame
APDB: a novel measure for benchmarking sequence alignment methods without reference alignments. ISMB (Supplement of Bioinformatics) (2003)
Steven D. Prestwich, Desmond G. Higgins, Orla O'Sullivan
A SAT-Based Approach to Multiple Sequence Alignment. CP (2003)
Aedín C. Culhane, Guy Perrière, Desmond G. Higgins
Cross-platform comparison and visualisation of gene expression data using co-inertia analysis. BMC Bioinform. 4 (2003)
Aedín C. Culhane, Guy Perrière, Elizabeth C. Considine, Thomas G. Cotter, Desmond G. Higgins
Between-group analysis of microarray data. Bioinform. 18 (12) (2002)
Patricia Thébault, Pierre Monestie, Annette McGrath, Desmond G. Higgins
MIAH: automatic alignment of eukaryotic SSU rRNAs. Bioinform. 15 (4) (1999)
Emmet A. O'Brien, Cédric Notredame, Desmond G. Higgins
Optimization of ribosomal RNA profile alignments. Bioinform. 14 (4) (1998)
Emmet A. O'Brien, Desmond G. Higgins
Empirical estimation of the reliability of ribosomal RNA alignments. Bioinform. 14 (10) (1998)
Cédric Notredame, Liisa Holm, Desmond G. Higgins
COFFEE: an objective function for multiple sequence alignments. Bioinform. 14 (5) (1998)
Julie Dawn Thompson, Desmond G. Higgins, Toby J. Gibson
Improved sensitivity of profile searches through the use of sequence weights and gap excision. Comput. Appl. Biosci. 10 (1) (1994)
Catherine M. Rice, Rainer Fuchs, Desmond G. Higgins, Peter Stoehr, Graham Cameron
The EMBL data library. Nucleic Acids Res. 21 (13) (1993)
Desmond G. Higgins
Sequence ordinations: a multivariate analysis approach to analysing large sequence data sets. Comput. Appl. Biosci. 8 (1) (1992)
Jaap Heringa, Hubert Sommerfeldt, Desmond G. Higgins, Patrick Argos
OBSTRUCT: a program to obtain largest cliques from a protein sequence set according to structural resolution and sequence similarity. Comput. Appl. Biosci. 8 (6) (1992)
Denis C. Shields, Desmond G. Higgins, P. M. Sharp
GCWIND: a microcomputer program for identifying open reading frames according to codon positional G+C content. Comput. Appl. Biosci. 8 (5) (1992)
Desmond G. Higgins, Alan J. Bleasby, Rainer Fuchs
CLUSTAL V: improved software for multiple sequence alignment. Comput. Appl. Biosci. 8 (2) (1992)
Desmond G. Higgins, Peter Stoehr
EMBLSCAN: fast approximate DNA database searches on compact disc. Comput. Appl. Biosci. 8 (2) (1992)
Desmond G. Higgins, P. M. Sharp
Fast and sensitive multiple sequence alignments on a microcomputer. Comput. Appl. Biosci. 5 (2) (1989)
Desmond G. Higgins, Manolo Gouy
Interfacing similarity search software with the sequence retrieval system ACNUC. Comput. Appl. Biosci. 3 (3) (1987)