Rainer Spang

Publication Activity (10 Years)

Years Active: 1997-2024
Publications (10 Years): 15

Top Topics

Sharing Platform

Kullback Leibler

Top Venues

J. Comput. Biol.

Publications

Michael Huttner, Jakob Simeth, Renato Liguori, Fulvia Ferrazzi, Rainer Spang
dabih - encrypted data storage and sharing platform. CoRR (2024)
Simon Pfahler, Peter Georg, Rudolf Schill, Maren Klever, Lars Grasedyck, Rainer Spang, Tilo Wettig
Taming numerical imprecision by adapting the KL divergence to negative probabilities. Stat. Comput. 34 (5) (2024)
Rudolf Schill, Maren Klever, Andreas Lösch, Y. Linda Hu, Stefan Vocht, Kevin Rupp, Lars Grasedyck, Rainer Spang, Niko Beerenwinkel
Overcoming Observation Bias for Cancer Progression Modeling. RECOMB (2024)
Lena Buck, Tobias Schmidt, Maren Feist, Philipp Schwarzfischer, Dieter Kube, Peter J. Oefner, Helena U. Zacharias, Michael Altenbuchinger, Katja Dettmer, Wolfram Gronwald, Rainer Spang
Anomaly detection in mixed high-dimensional molecular data. Bioinform. 39 (8) (2023)
Stefan Schrod, Andreas Schäfer, Stefan Solbrig, Robert Lohmayer, Wolfram Gronwald, Peter J. Oefner, Tim Beißbarth, Rainer Spang, Helena U. Zacharias, Michael Altenbuchinger
BITES: Balanced Individual Treatment Effect for Survival data. CoRR (2022)
Kevin Rupp, Rudolf Schill, Jonas Süskind, Peter Georg, Maren Klever, Andreas Lösch, Lars Grasedyck, Tilo Wettig, Rainer Spang
Differentiated uniformization: A new method for inferring Markov chains on combinatorial state spaces including stochastic epidemic models. CoRR (2021)
Franziska Görtler, Marian Schön, Jakob Simeth, Stefan Solbrig, Tilo Wettig, Peter J. Oefner, Rainer Spang, Michael Altenbuchinger
Loss-Function Learning for Digital Tissue Deconvolution. J. Comput. Biol. 27 (3) (2020)
Rudolf Schill, Stefan Solbrig, Tilo Wettig, Rainer Spang
Modelling cancer progression using Mutual Hazard Networks. Bioinform. 36 (1) (2020)
Marian Schön, Jakob Simeth, Paul Heinrich, Franziska Görtler, Stefan Solbrig, Tilo Wettig, Peter J. Oefner, Michael Altenbuchinger, Rainer Spang
DTD: An R Package for Digital Tissue Deconvolution. J. Comput. Biol. 27 (3) (2020)
Peter Georg, Lars Grasedyck, Maren Klever, Rudolf Schill, Rainer Spang, Tilo Wettig
Low-rank tensor methods for Markov chains with applications to tumor progression models. CoRR (2020)
Franziska Görtler, Stefan Solbrig, Tilo Wettig, Peter J. Oefner, Rainer Spang, Michael Altenbuchinger
Loss-Function Learning for Digital Tissue Deconvolution. RECOMB (2018)
Michael Altenbuchinger, Thorsten Rehberg, H. U. Zacharias, Frank Stämmler, K. Dettmer, D. Weber, Andreas Hiergeist, A. Gessner, E. Holler, Peter J. Oefner, Rainer Spang
Reference point insensitive molecular data analysis. Bioinform. 33 (2) (2017)
Michael Altenbuchinger, Philipp Schwarzfischer, Thorsten Rehberg, Jörg Reinders, Christian W. Kohler, Wolfram Gronwald, Julia Richter, Monika Szczepanowski, Neus Masqué-Soler, Wolfram Klapper, Peter J. Oefner, Rainer Spang
Molecular signatures that can be transferred across different omics platforms. Bioinform. 33 (14) (2017)
Michael Altenbuchinger, Philipp Schwarzfischer, Thorsten Rehberg, Jörg Reinders, Christian W. Kohler, Wolfram Gronwald, Julia Richter, Monika Szczepanowski, Neus Masqué-Soler, Wolfram Klapper, Peter J. Oefner, Rainer Spang
Molecular signatures that can be transferred across different omics platforms. Bioinform. 33 (17) (2017)
Martin Pirkl, Elisabeth Hand, Dieter Kube, Rainer Spang
Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models. Bioinform. 32 (6) (2016)
Franziska Taruttis, Rainer Spang, Julia C. Engelmann
A statistical approach to virtual cellular experiments: improved causal discovery using accumulation IDA (aIDA). Bioinform. 31 (23) (2015)
Julia C. Engelmann, Thomas Amann, Birgitta Ott-Rötzer, Margit Nützel, Yvonne Reinders, Jörg Reinders, Wolfgang E. Thasler, Theresa Kristl, Andreas Teufel, Christian G. Huber, Peter J. Oefner, Rainer Spang, Claus Hellerbrand
Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFκB Signaling in Hepatocellular Carcinoma. PLoS Comput. Biol. 11 (5) (2015)
Sebastian Dümcke, Johannes Bräuer, Benedict Anchang, Rainer Spang, Niko Beerenwinkel, Achim Tresch
Exact likelihood computation in Boolean networks with probabilistic time delays, and its application in signal network reconstruction. Bioinform. 30 (3) (2014)
Mohammad Javad Sadeh, Giusi Moffa, Rainer Spang
Considering Unknown Unknowns - Reconstruction of Non-confoundable Causal Relations in Biological Networks. RECOMB (2013)
Mohammad Javad Sadeh, Giusi Moffa, Rainer Spang
Considering Unknown Unknowns: Reconstruction of Nonconfoundable Causal Relations in Biological Networks. J. Comput. Biol. 20 (11) (2013)
Matthias Maneck, Alexandra Schrader, Dieter Kube, Rainer Spang
Genomic data integration using guided clustering. Bioinform. 27 (16) (2011)
Inka J. Appel, Wolfram Gronwald, Rainer Spang
Estimating classification probabilities in high-dimensional diagnostic studies. Bioinform. 27 (18) (2011)
Marian Thieme, Claudio Lottaz, Harald Niederstätter, Walther Parson, Rainer Spang, Peter J. Oefner
ReseqChip: Automated integration of multiple local context probe data from the MitoChip array in mitochondrial DNA sequence assembly. BMC Bioinform. 10 (2009)
Dennis Kostka, Rainer Spang
Microarray Based Diagnosis Profits from Better Documentation of Gene Expression Signatures. PLoS Comput. Biol. 4 (2) (2008)
Juby Jacob, Marcel Jentsch, Dennis Kostka, Stefan Bentink, Rainer Spang
Detecting hierarchical structure in molecular characteristics of disease using transitive approximations of directed graphs. Bioinform. 24 (7) (2008)
Holger Fröhlich, Tim Beißbarth, Achim Tresch, Dennis Kostka, Juby Jacob, Rainer Spang, Florian Markowetz
Analyzing gene perturbation screens with nested effects models in R and bioconductor. Bioinform. 24 (21) (2008)
Stefanie Scheid, Rainer Spang
Compensating for Unknown Confounders in Microarray Data Analysis Using Filtered Permutations. J. Comput. Biol. 14 (5) (2007)
Florian Markowetz, Dennis Kostka, Olga G. Troyanskaya, Rainer Spang
Nested effects models for high-dimensional phenotyping screens. ISMB/ECCB (Supplement of Bioinformatics) (2007)
Florian Markowetz, Rainer Spang
Inferring cellular networks - a review. BMC Bioinform. 8 (S-6) (2007)
Claudio Lottaz, Joern Toedling, Rainer Spang
Annotation-based distance measures for patient subgroup discovery in clinical microarray studies. Bioinform. 23 (17) (2007)
Claudio Lottaz, Xinan Yang, Stefanie Scheid, Rainer Spang
- a bioconductor package for detecting similarity in ordered gene lists. Bioinform. 22 (18) (2006)
Xinan Yang, Stefan Bentink, Stefanie Scheid, Rainer Spang
Similarities of Ordered Gene Lists. J. Bioinform. Comput. Biol. 4 (3) (2006)
Jochen Jaeger, Rainer Spang
Selecting normalization genes for small diagnostic microarrays. BMC Bioinform. 7 (2006)
Claudio Lottaz, Joern Toedling, Rainer Spang
Annotation-based Distance Measures for Patient Subgroup Discovery in Clinical Microarray Studies. German Conference on Bioinformatics (2006)
Joern Toedling, Peter Rhein, Richard Ratei, Leonid Karawajew, Rainer Spang
Automated in-silico detection of cell populations in flow cytometry readouts and its application to leukemia disease monitoring. BMC Bioinform. 7 (2006)
Stefanie Scheid, Rainer Spang
Permutation Filtering: A Novel Concept for Significance Analysis of Large-Scale Genomic Data. RECOMB (2006)
Florian Markowetz, Jacques Bloch, Rainer Spang
Non-transcriptional pathway features reconstructed from secondary effects of RNA interference. Bioinform. 21 (21) (2005)
Florian Markowetz, Steffen Grossmann, Rainer Spang
Probabilistic Soft Interventions in Conditional Gaussian Networks. AISTATS (2005)
Claudio Lottaz, Rainer Spang
stam - a Bioconductor compliant R package for structured analysis of microarray data. BMC Bioinform. 6 (2005)
Claudio Lottaz, Rainer Spang
Molecular decomposition of complex clinical phenotypes using biologically structured analysis of microarray data. Bioinform. 21 (9) (2005)
Stefanie Scheid, Rainer Spang
twilight; a Bioconductor package for estimating the local false discovery rate. Bioinform. 21 (12) (2005)
Stefanie Scheid, Rainer Spang
A Stochastic Downhill Search Algorithm for Estimating the Local False Discovery Rate. IEEE ACM Trans. Comput. Biol. Bioinform. 1 (3) (2004)
Dennis Kostka, Rainer Spang
Finding disease specific alterations in the co-expression of genes. ISMB/ECCB (Supplement of Bioinformatics) (2004)
Rainer Spang, Marc Rehmsmeier, Jens Stoye
A Novel Approach to Remote Homology Detection: Jumping Alignments. J. Comput. Biol. 9 (5) (2002)
Rainer Spang, Carrie Blanchette, Harry Zuzan, Jeffrey R. Marks, Joseph Nevins, Mike West
Prediction and uncertainty in the analysis of gene expression profiles. Silico Biol. 2 (3) (2002)
Constantin Bannert, Marc Rehmsmeier, Rainer Spang, Jens Stoye
Sequence Database Search Using Jumping Alignments. German Conference on Bioinformatics (2001)
Rainer Spang, Carrie Blanchette, Harry Zuzan, Jeffrey R. Marks, Joseph Nevins, Mike West
Prediction and uncertainty in the analysis of gene expression profiles. German Conference on Bioinformatics (2001)
Rainer Spang, Martin Vingron
Limits of homology detection by pairwise sequence comparison. Bioinform. 17 (4) (2001)
Rainer Spang, Marc Rehmsmeier, Jens Stoye
Sequence Database Search Using Jumping Alignments. ISMB (2000)
Tobias Müller, Rainer Spang, Martin Vingron
A new method for modeling protein evolution. German Conference on Bioinformatics (1999)
Rainer Spang, Martin Vingron
Statistics of large-scale sequence searching. Bioinform. 14 (3) (1998)
Rainer Spang, Martin Vingron
Statistics of large scale sequence searching. German Conference on Bioinformatics (1997)