PhenoGene: Disease-gene prioritization using graph embedding on patient phenotypic profiles.
Shankai YanLing LuoLi FangDaniel VeltriAndrew J. OlerRajarshi GhoshChih-Hsuan WeiMorgan SimilukKai WangZhiyong LuPublished in: AMIA (2022)
Keyphrases
- graph embedding
- single nucleotide polymorphisms
- gene regulatory networks
- biological processes
- patient groups
- discriminant analysis
- semi supervised
- low dimensional
- dimensionality reduction
- data representation
- gene expression
- copy number
- microarray
- discriminant embedding
- subspace learning
- dictionary learning
- gene sets
- high throughput
- gene expression data
- genome wide
- dna sequences
- pattern recognition
- label information
- principal component analysis
- gene ontology
- training data
- high dimensional
- image features
- user profiles
- geometric properties
- feature representation
- microarray data