Pairwise statistical significance and empirical determination of effective gap opening penalties for protein local sequence alignment.
Ankit AgrawalVolker BrendelXiaoqiu HuangPublished in: Int. J. Comput. Biol. Drug Des. (2008)
Keyphrases
- sequence alignment
- pairwise
- statistical significance
- binding sites
- psi blast
- statistically significant
- amino acids
- multiple sequence alignment
- dynamic programming
- multiple alignment
- machine learning
- statistical tests
- smith waterman
- transcription factors
- protein sequences
- protein structure prediction
- comparative genomics
- data distribution
- similarity measure