HMMvar-func: a new method for predicting the functional outcome of genetic variants.
Mingming LiuLayne T. WatsonLiqing ZhangPublished in: BMC Bioinform. (2015)
Keyphrases
- significant improvement
- synthetic data
- main contribution
- cost function
- experimental evaluation
- high precision
- detection method
- preprocessing
- bayesian networks
- computational cost
- segmentation method
- mutual information
- theoretical analysis
- fully automatic
- optimization algorithm
- computationally efficient
- image quality
- edge detection
- support vector machine
- dynamic programming