Protein Surface Softness Is the Origin of Enzyme Cold-Adaptation of Trypsin.
Geir Villy IsaksenJohan ÅqvistBjørn Olav BrandsdalPublished in: PLoS Comput. Biol. (2014)
Keyphrases
- amino acids
- protein folding
- drug discovery
- protein sequences
- predicting protein
- surface features
- protein structure prediction
- range data
- surface reconstruction
- three dimensional
- protein families
- object surface
- protein protein interactions
- d objects
- surface fitting
- adaptation process
- contact map
- dead end
- signal transduction
- surface points
- amino acid sequences
- protein function
- secondary structure
- complex networks
- viewpoint
- search algorithm