DDGun: an untrained method for the prediction of protein stability changes upon single and multiple point variations.
Ludovica MontanucciEmidio CapriottiYotam FrankNir Ben-TalPiero FariselliPublished in: BMC Bioinform. (2019)
Keyphrases
- high precision
- preprocessing
- significant improvement
- high accuracy
- contact map
- feature set
- model selection
- support vector machine svm
- similarity measure
- computational complexity
- prediction model
- detection method
- support vector machine
- stability analysis
- multiple objects
- neural network
- probabilistic model
- computational cost
- dynamic programming
- cost function
- genetic algorithm