Detecting SNPs and estimating allele frequencies in clonal bacterial populations by sequencing pooled DNA.
Kathryn E. HoltYik Y. TeoHeng LiSatheesh NairGordon DouganJohn WainJulian ParkhillPublished in: Bioinform. (2009)
Keyphrases
- dna sequences
- single nucleotide polymorphisms
- convergence speed
- genome wide
- particle swarm optimization
- high throughput sequencing
- human genome
- multiobjective optimization
- computational biology
- complex diseases
- coding regions
- machine learning
- binding sites
- highly correlated
- biological sequences
- sequence analysis
- dna computing