Yu Zong Chen

Publication Activity (10 Years)

Years Active: 2002-2023
Publications (10 Years): 17

Top Topics

Clinical Trials

Subcellular Localization

Top Venues

Nucleic Acids Res.

Briefings Bioinform.

Comput. Biol. Medicine

Publications

Tianyi Wang, Ying Tan, Yu Zong Chen, Chunyan Tan
Infrared Spectral Analysis for Prediction of Functional Groups Based on Feature-Aggregated Deep Learning. J. Chem. Inf. Model. 63 (15) (2023)
Wan Xiang Shen, Shu Ran Liang, Yu Yang Jiang, Yu Zong Chen
Enhanced metagenomic deep learning for disease prediction and consistent signature recognition by restructured microbiome 2D representations. Patterns 4 (1) (2023)
Kai Ping Cheng, Wan Xiang Shen, Yu Yang Jiang, Yan Chen, Yu Zong Chen, Ying Tan
Deep learning of 2D-Restructured gene expression representations for improved low-sample therapeutic response prediction. Comput. Biol. Medicine 164 (2023)
Hui Zhao, Yuan Yang, Shuaiqi Wang, Xue Yang, Kaicheng Zhou, Caili Xu, Xuyao Zhang, Jiajun Fan, Dongyue Hou, Xingxiu Li, Hanbo Lin, Ying Tan, Shanshan Wang, Xinyi Chu, Dongzhi Zhuoma, Fengying Zhang, Dianwen Ju, Xian Zeng, Yu Zong Chen
NPASS database update 2023: quantitative natural product activity and species source database for biomedical research. Nucleic Acids Res. 51 (D1) (2023)
Wan Xiang Shen, Yu Zong Chen
Toward ordered -omics data science: Researchers on the magic of turning metagenomic chaos into image-like patterns. Patterns 4 (1) (2023)
Shanshan Wang, Yu Zong Chen, Songsen Fu, Yufen Zhao
-phosphorylated proteins in human cells. Comput. Biol. Medicine 151 (Part) (2022)
Jing-Fang Yang, Fan Wang, Yu Zong Chen, Ge-Fei Hao, Guangfu Yang
Erratum to: LARMD: integration of bioinformatic resources to profile ligand-driven protein dynamics with a case on the activation of estrogen receptor. Briefings Bioinform. 22 (1) (2021)
Xian Zeng, Xue Yang, Jiajun Fan, Ying Tan, Lingyi Ju, Wanxiang Shen, Yali Wang, Xinghao Wang, Weiping Chen, Dianwen Ju, Yu Zong Chen
MASI: microbiota - active substance interactions database. Nucleic Acids Res. 49 (Database-Issue) (2021)
Wan Xiang Shen, Xian Zeng, Feng Zhu, Ya li Wang, Chu Qin, Ying Tan, Yu Yang Jiang, Yu Zong Chen
Out-of-the-box deep learning prediction of pharmaceutical properties by broadly learned knowledge-based molecular representations. Nat. Mach. Intell. 3 (4) (2021)
Lu Lu, Yu Zong Chen, Tony Tae-Hyoung Kim
A Configurable Randomness Enhanced RRAM PUF with Biased Current Sensing Scheme. ISCAS (2021)
Jing-Fang Yang, Fan Wang, Yu Zong Chen, Ge-Fei Hao, Guangfu Yang
LARMD: integration of bioinformatic resources to profile ligand-driven protein dynamics with a case on the activation of estrogen receptor. Briefings Bioinform. 21 (6) (2020)
Ying Hong Li, Xiao Xu Li, Jiajun Hong, Yunxia Wang, Jianbo Fu, Hong Yang, Chun Yan Yu, Feng Cheng Li, Jie Hu, Weiwei Xue, Yu Yang Jiang, Yu Zong Chen, Feng Zhu
Clinical trials, progression-speed differentiating features and swiftness rule of the innovative targets of first-in-class drugs. Briefings Bioinform. 21 (2) (2020)
Xian Zeng, Peng Zhang, Yali Wang, Chu Qin, Shangying Chen, Weidong He, Lin Tao, Ying Tan, Dan Gao, Bo-hua Wang, Zhe Chen, Weiping Chen, Yu Yang Jiang, Yu Zong Chen
CMAUP: a database of collective molecular activities of useful plants. Nucleic Acids Res. 47 (Database-Issue) (2019)
Xian Zeng, Peng Zhang, Weidong He, Chu Qin, Shangying Chen, Lin Tao, Yali Wang, Ying Tan, Dan Gao, Bo-hua Wang, Zhe Chen, Weiping Chen, Yu Yang Jiang, Yu Zong Chen
NPASS: natural product activity and species source database for natural product research, discovery and tool development. Nucleic Acids Res. 46 (Database-Issue) (2018)
Ying Hong Li, Chun Yan Yu, Xiao Xu Li, Peng Zhang, Jing Tang, Qingxia Yang, Tingting Fu, Xiaoyu Zhang, Xuejiao Cui, Gao Tu, Yang Zhang, Shuang Li, Fengyuan Yang, Qiu Sun, Chu Qin, Xian Zeng, Zhe Chen, Yu Zong Chen, Feng Zhu
Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics. Nucleic Acids Res. 46 (Database-Issue) (2018)
Xian Zeng, Lin Tao, Peng Zhang, Chu Qin, Shangying Chen, Weidong He, Ying Tan, Hong Xia Liu, Sheng-Yong Yang, Zhe Chen, Yu Yang Jiang, Yu Zong Chen
HEROD: a human ethnic and regional specific omics database. Bioinform. 33 (20) (2017)
Hong Yang, Chu Qin, Ying Hong Li, Lin Tao, Jin Zhou, Chun Yan Yu, Feng Xu, Zhe Chen, Feng Zhu, Yu Zong Chen
Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information. Nucleic Acids Res. 44 (Database-Issue) (2016)
Cheng Zhang, Lin Tao, Chu Qin, Peng Zhang, Shangying Chen, Xian Zeng, Feng Xu, Zhe Chen, Sheng-Yong Yang, Yu Zong Chen
CFam: a chemical families database based on iterative selection of functional seeds and seed-directed compound clustering. Nucleic Acids Res. 43 (Database-Issue) (2015)
Chu Qin, Cheng Zhang, Feng Zhu, Feng Xu, Shangying Chen, Peng Zhang, Ying Hong Li, Sheng-Yong Yang, Yu-Quan Wei, Lin Tao, Yu Zong Chen
Therapeutic target database update 2014: a resource for targeted therapeutics. Nucleic Acids Res. 42 (Database-Issue) (2014)
Shu Zhou, Guo-Bo Li, Lu-Yi Huang, Huan-Zhang Xie, Ying-Lan Zhao, Yu Zong Chen, Lin-Li Li, Sheng-Yong Yang
A prediction model of drug-induced ototoxicity developed by an optimal support vector machine (SVM) method. Comput. Biol. Medicine 51 (2014)
Ju He, Guobing Yang, Hanbing Rao, Ze-Rong Li, Xianping Ding, Yu Zong Chen
Prediction of human major histocompatibility complex class II binding peptides by continuous kernel discrimination method. Artif. Intell. Medicine 55 (2) (2012)
XiaoNa Wei, Bu-Cong Han, Jing-Xian Zhang, X. H. Liu, C. Y. Tan, Y. Y. Jiang, Boon Chuan Low, Bruce Tidor, Yu Zong Chen
An Integrated Mathematical Model of Thrombin-, Histamine-and VEGF-Mediated Signalling in Endothelial Permeability. BMC Syst. Biol. 5 (2011)
Hao Ye, Li Ye, Hong Kang, Duanfeng Zhang, Lin Tao, Kailin Tang, Xueping Liu, Ruixin Zhu, Qi Liu, Yu Zong Chen, Yixue Li, Zhi-Wei Cao
HIT: linking herbal active ingredients to targets. Nucleic Acids Res. 39 (Database-Issue) (2011)
Pankaj Kumar, Xiao Hua Ma, Xianghui Liu, Jia Jia, Bu-Cong Han, Ying Xue, Ze-Rong Li, Sheng-Yong Yang, Yu-Quan Wei, Yu Zong Chen
Effect of training data size and noise level on support vector machines virtual screening of genotoxic compounds from large compound libraries. J. Comput. Aided Mol. Des. 25 (5) (2011)
H. B. Rao, F. Zhu, G. B. Yang, Z. R. Li, Yu Zong Chen
Update of PROFEAT: a web server for computing structural and physicochemical features of proteins and peptides from amino acid sequence. Nucleic Acids Res. 39 (Web-Server-Issue) (2011)
Hanbing Rao, Ze-Rong Li, Xiang-Yuan Li, Xiao Hua Ma, Choong Yong Ung, Hu Li, Xianghui Liu, Yu Zong Chen
Identification of small molecule aggregators from large compound libraries by support vector machines. J. Comput. Chem. 31 (4) (2010)
Xue-Gang Yang, Wei Lv, Yu Zong Chen, Ying Xue
prediction and screening of gamma-secretase inhibitors by molecular descriptors and machine learning methods. J. Comput. Chem. 31 (6) (2010)
Feng Zhu, Bu-Cong Han, Pankaj Kumar, Xianghui Liu, Xiao Hua Ma, XiaoNa Wei, Lu Huang, Yangfan Guo, LianYi Han, ChanJuan Zheng, Yu Zong Chen
Update of TTD: Therapeutic Target Database. Nucleic Acids Res. 38 (Database-Issue) (2010)
X. H. Liu, Xiao Hua Ma, C. Y. Tan, Y. Y. Jiang, M. L. Go, Boon Chuan Low, Yu Zong Chen
Virtual Screening of Abl Inhibitors from Large Compound Libraries by Support Vector Machines. J. Chem. Inf. Model. 49 (9) (2009)
Xue-Gang Yang, Duan Chen, Min Wang, Ying Xue, Yu Zong Chen
Prediction of antibacterial compounds by machine learning approaches. J. Comput. Chem. 30 (8) (2009)
Pankaj Kumar, Bu-Cong Han, Z. Shi, Jia Jia, Yupeng Wang, Y. T. Zhang, L. Liang, Q. F. Liu, Zhi Liang Ji, Yu Zong Chen
Update of KDBI: Kinetic Data of Bio-molecular Interaction database. Nucleic Acids Res. 37 (Database-Issue) (2009)
Rong Wang, Jian-Sheng Wang, Gui-Rong Liu, Jongyoon Han, Yu Zong Chen
Simulation of DNA electrophoresis in systems of large number of solvent particles by coarse-grained hybrid molecular dynamics approach. J. Comput. Chem. 30 (4) (2009)
Hu Li, Choong Yong Ung, Xiao Hua Ma, Bao Wen Li, Boon Chuan Low, Zhi Wei Cao, Yu Zong Chen
Simulation of crosstalk between small GTPase RhoA and EGFR-ERK signaling pathway via MEKK1. Bioinform. 25 (3) (2009)
Xiao Hua Ma, R. Wang, S. Y. Yang, Z. R. Li, Ying Xue, Y. C. Wei, Boon Chuan Low, Yu Zong Chen
Evaluation of Virtual Screening Performance of Support Vector Machines Trained by Sparsely Distributed Active Compounds. J. Chem. Inf. Model. 48 (6) (2008)
C. J. Zheng, L. Y. Han, B. Xie, C. Y. Liew, S. Ong, J. Cui, H. L. Zhang, Z. Q. Tang, S. H. Gan, L. Jiang, Yu Zong Chen
PharmGED: Pharmacogenetic Effect Database. Nucleic Acids Res. 35 (Database-Issue) (2007)
Jing-Xian Zhang, Wei-Juan Huang, Jing-Hua Zeng, Wen-Hui Huang, Yi Wang, Rui Zhao, Bu-Cong Han, Qing-Feng Liu, Yu Zong Chen, Zhi Liang Ji
DITOP: drug-induced toxicity related protein database. Bioinform. 23 (13) (2007)
Serene A. K. Ong, Honghuang Lin, Yu Zong Chen, Ze-Rong Li, Zhi Wei Cao
Efficacy of different protein descriptors in predicting protein functional families. BMC Bioinform. 8 (2007)
L. Y. Han, Honghuang Lin, Ze-Rong Li, C. J. Zheng, Zhi Wei Cao, B. Xie, Yu Zong Chen
PEARLS: Program for Energetic Analysis of Receptor-Ligand System. J. Chem. Inf. Model. 46 (1) (2006)
Ze-Rong Li, Honghuang Lin, L. Y. Han, L. Jiang, X. Chen, Yu Zong Chen
PROFEAT: a web server for computing structural and physicochemical features of proteins and peptides from amino acid sequence. Nucleic Acids Res. 34 (Web-Server-Issue) (2006)
H. H. Lin, L. Y. Han, H. L. Zhang, C. J. Zheng, B. Xie, Zhi Wei Cao, Yu Zong Chen
Prediction of the functional class of metal-binding proteins from sequence derived physicochemical properties by support vector machine approach. BMC Bioinform. 7 (S-5) (2006)
C. Z. Cai, Q. F. Yuan, H. G. Xiao, X. H. Liu, L. Y. Han, Yu Zong Chen
Prediction of Transmembrane Proteins from Their Primary Sequence by Support Vector Machine Approach. ICIC (3) (2006)
Hu Li, Chun Wei Yap, Choong Yong Ung, Ying Xue, Zhi Wei Cao, Yu Zong Chen
Effect of Selection of Molecular Descriptors on the Prediction of Blood-Brain Barrier Penetrating and Nonpenetrating Agents by Statistical Learning Methods. J. Chem. Inf. Model. 45 (5) (2005)
Chun Wei Yap, Yu Zong Chen
Prediction of Cytochrome P450 3A4, 2D6, and 2C9 Inhibitors and Substrates by Using Support Vector Machines. J. Chem. Inf. Model. 45 (4) (2005)
J. F. Wang, Z. R. Li, C. Z. Cai, Yu Zong Chen
Assessment of approximate string matching in a biomedical text retrieval problem. Comput. Biol. Medicine 35 (8) (2005)
Ying Xue, Chun Wei Yap, Li Zhi Sun, Zhi Wei Cao, J. F. Wang, Yu Zong Chen
Prediction of P-Glycoprotein Substrates by a Support Vector Machine Approach. J. Chem. Inf. Model. 44 (4) (2004)
Ying Xue, Ze-Rong Li, Chun Wei Yap, Li Zhi Sun, Xin Chen, Yu Zong Chen
Effect of Molecular Descriptor Feature Selection in Support Vector Machine Classification of Pharmacokinetic and Toxicological Properties of Chemical Agents. J. Chem. Inf. Model. 44 (5) (2004)
C. J. Zheng, H. Zhou, B. Xie, L. Y. Han, Chun Wei Yap, Yu Zong Chen
TRMP: a database of therapeutically relevant multiple pathways. Bioinform. 20 (14) (2004)
Zhi Wei Cao, Ying Xue, L. Y. Han, B. Xie, H. Zhou, C. J. Zheng, Honghuang Lin, Yu Zong Chen
MoViES: molecular vibrations evaluation server for analysis of fluctuational dynamics of proteins and nucleic acids. Nucleic Acids Res. 32 (Web-Server-Issue) (2004)
C. Z. Cai, L. Y. Han, Zhi Liang Ji, X. Chen, Yu Zong Chen
SVM-Prot: web-based support vector machine software for functional classification of a protein from its primary sequence. Nucleic Acids Res. 31 (13) (2003)
Zhi Liang Ji, X. Chen, C. J. Zheng, L. X. Yao, L. Y. Han, Wee Kiang Yeo, P. C. Chung, H. S. Puy, Y. T. Tay, A. Muhammad, Yu Zong Chen
KDBI: Kinetic Data of Bio-molecular Interactions database. Nucleic Acids Res. 31 (1) (2003)
X. Chen, Zhi Liang Ji, Yu Zong Chen
TTD: Therapeutic Target Database. Nucleic Acids Res. 30 (1) (2002)
Li Zhi Sun, Zhi Liang Ji, Xin Chen, J. F. Wang, Yu Zong Chen
ADME-AP: a database of ADME associated proteins. Bioinform. 18 (12) (2002)
X. Chen, Zhi Liang Ji, D. G. Zhi, Yu Zong Chen
CLiBE: A Database of Computed Ligand Binding Energy for Ligand-receptor Complexes. Comput. Chem. 26 (6) (2002)