Sheng-Yong Yang

Publication Activity (10 Years)

Years Active: 2007-2024
Publications (10 Years): 6

Top Topics

Generative Model

Support Vector Machine

Top Venues

J. Chem. Inf. Model.

Nucleic Acids Res.

Briefings Bioinform.

Publications

Yuanyuan Jiang, Guo Zhang, Jing You, Hailin Zhang, Rui Yao, Huan-Zhang Xie, Liyun Zhang, Ziyi Xia, Mengzhe Dai, Yunjie Wu, Linli Li, Sheng-Yong Yang
PocketFlow is a data-and-knowledge-driven structure-based molecular generative model. Nat. Mac. Intell. 6 (3) (2024)
Xin Yang, Guifeng Lin, Anjie Xia, Jingming Liu, Shiyu Zhang, Pei Zhou, Yiwei Wang, Jiahao Zhang, Yangli Zhou, Pei Chen, Yifei Wang, Tao Zheng, Linli Li, Sheng-Yong Yang
Discovery of Small Molecule Agonist of Gonadotropin-Releasing Hormone Receptor (GnRH1R). J. Chem. Inf. Model. 62 (20) (2022)
Feixiong Cheng, Huixiao Hong, Sheng-Yong Yang, Yuquan Wei
Individualized network-based drug repositioning infrastructure for precision oncology in the panomics era. Briefings Bioinform. 18 (4) (2017)
Shenzhen Huang, Chunli Song, Xiang Wang, Guo Zhang, Yanlin Wang, Xiaojuan Jiang, Qizheng Sun, Luyi Huang, Rong Xiang, Yiguo Hu, Linli Li, Sheng-Yong Yang
Discovery of New SIRT2 Inhibitors by Utilizing a Consensus Docking/Scoring Strategy and Structure-Activity Relationship Analysis. J. Chem. Inf. Model. 57 (4) (2017)
Xian Zeng, Lin Tao, Peng Zhang, Chu Qin, Shangying Chen, Weidong He, Ying Tan, Hong Xia Liu, Sheng-Yong Yang, Zhe Chen, Yu Yang Jiang, Yu Zong Chen
HEROD: a human ethnic and regional specific omics database. Bioinform. 33 (20) (2017)
Guo-Bo Li, Zhu-Jun Yu, Sha Liu, Lu-Yi Huang, Ling-Ling Yang, Christopher T. Lohans, Sheng-Yong Yang
IFPTarget: A Customized Virtual Target Identification Method Based on Protein-Ligand Interaction Fingerprinting Analyses. J. Chem. Inf. Model. 57 (7) (2017)
Cheng Zhang, Lin Tao, Chu Qin, Peng Zhang, Shangying Chen, Xian Zeng, Feng Xu, Zhe Chen, Sheng-Yong Yang, Yu Zong Chen
CFam: a chemical families database based on iterative selection of functional seeds and seed-directed compound clustering. Nucleic Acids Res. 43 (Database-Issue) (2015)
Chu Qin, Cheng Zhang, Feng Zhu, Feng Xu, Shangying Chen, Peng Zhang, Ying Hong Li, Sheng-Yong Yang, Yu-Quan Wei, Lin Tao, Yu Zong Chen
Therapeutic target database update 2014: a resource for targeted therapeutics. Nucleic Acids Res. 42 (Database-Issue) (2014)
Shu Zhou, Guo-Bo Li, Lu-Yi Huang, Huan-Zhang Xie, Ying-Lan Zhao, Yu Zong Chen, Lin-Li Li, Sheng-Yong Yang
A prediction model of drug-induced ototoxicity developed by an optimal support vector machine (SVM) method. Comput. Biol. Medicine 51 (2014)
Guo-Bo Li, Ling-Ling Yang, Wen-Jing Wang, Lin-Li Li, Sheng-Yong Yang
ID-Score: A New Empirical Scoring Function Based on a Comprehensive Set of Descriptors Related to Protein-Ligand Interactions. J. Chem. Inf. Model. 53 (3) (2013)
Lei Zhong, Chang-Ying Ma, Hui Zhang, Li-Jun Yang, Hua-Lin Wan, Qing-Qing Xie, Lin-Li Li, Sheng-Yong Yang
A prediction model of substrates and non-substrates of breast cancer resistance protein (BCRP) developed by GA-CG-SVM method. Comput. Biol. Medicine 41 (11) (2011)
Pankaj Kumar, Xiao Hua Ma, Xianghui Liu, Jia Jia, Bu-Cong Han, Ying Xue, Ze-Rong Li, Sheng-Yong Yang, Yu-Quan Wei, Yu Zong Chen
Effect of training data size and noise level on support vector machines virtual screening of genotoxic compounds from large compound libraries. J. Comput. Aided Mol. Des. 25 (5) (2011)
Ji-Xia Ren, Lin-Li Li, Ren-Lin Zheng, Huan-Zhang Xie, Zhi-Xing Cao, Shan Feng, You-Li Pan, Xin Chen, Yu-Quan Wei, Sheng-Yong Yang
Discovery of Novel Pim-1 Kinase Inhibitors by a Hierarchical Multistage Virtual Screening Approach Based on SVM Model, Pharmacophore, and Molecular Docking. J. Chem. Inf. Model. 51 (6) (2011)
Qi Huang, Lin-Li Li, Sheng-Yong Yang
RASA: A Rapid Retrosynthesis-Based Scoring Method for the Assessment of Synthetic Accessibility of Drug-like Molecules. J. Chem. Inf. Model. 51 (10) (2011)
Sheng-Yong Yang, Qi Huang, Lin-Li Li, Chang-Ying Ma, Hui Zhang, Ru Bai, Qizhi Teng, Ming-Li Xiang, Yu-Quan Wei
An integrated scheme for feature selection and parameter setting in the support vector machine modeling and its application to the prediction of pharmacokinetic properties of drugs. Artif. Intell. Medicine 46 (2) (2009)
Sheng-Yong Yang, Ming-Li Xiang, Li-Juan Chen, Guo-Bin Xie, Bing Shi, Yu-Quan Wei, Tom Ziegler
molecular dynamics study. J. Comput. Chem. 28 (2) (2007)