Leslie A. Kuhn

Publication Activity (10 Years)

Years Active: 1997-2022
Publications (10 Years): 4

Top Topics

Amino Acid Sequences

Subcellular Localization

Molecular Biology

Top Venues

J. Comput. Aided Mol. Des.

J. Chem. Inf. Model.

Publications

Veerabahu Shanmugasundaram, Jürgen Bajorath, Ralph E. Christoffersen, James D. Petke, W. Jeffrey Howe, Mark A. Johnson, Dimitris K. Agrafiotis, Pil Lee, Leslie A. Kuhn, Jay T. Goodwin, M. Katharine Holloway, Thompson N. Doman, W. Patrick Walters, Suzanne K. Schreyer, José L. Medina-Franco, Karina Martínez-Mayorga, Linda L. Restifo
Epilogue to the Gerald Maggiora Festschrift: a tribute to an exemplary mentor, colleague, collaborator, and innovator. J. Comput. Aided Mol. Des. 36 (9) (2022)
Sebastian Raschka, Alex J. Wolf, Joseph Bemister-Buffington, Leslie A. Kuhn
Protein-ligand interfaces are polarized: discovery of a strong trend for intermolecular hydrogen bonds to favor donors on the protein side with implications for predicting and designing ligand complexes. J. Comput. Aided Mol. Des. 32 (4) (2018)
Sebastian Raschka, Anne M. Scott, Nan Liu, Santosh Gunturu, Mar Huertas, Weiming Li, Leslie A. Kuhn
Enabling the hypothesis-driven prioritization of ligand candidates in big databases: Screenlamp and its application to GPCR inhibitor discovery for invasive species control. J. Comput. Aided Mol. Des. 32 (3) (2018)
Nan Liu, Jeffrey R. Van Voorst, John B. Johnston, Leslie A. Kuhn
CholMine: Determinants and Prediction of Cholesterol and Cholate Binding Across Nonhomologous Protein Structures. J. Chem. Inf. Model. 55 (4) (2015)
Jeffrey R. Van Voorst, Yiying Tong, Leslie A. Kuhn
ArtSurf: a method for deformable partial matching of protein small-molecule binding sites. BCB (2012)
Sai Chetan K. Sukuru, Thibaut Crepin, Youli Milev, Liesl C. Marsh, Jonathan B. Hill, Regan J. Anderson, Jonathan C. Morris, Anjali Rohatgi, Gavin O'Mahony, Morten Grøtli, Franck Danel, Malcolm G. P. Page, Michael Härtlein, Stephen Cusack, Michael A. Kron, Leslie A. Kuhn
Asparaginyl-tRNA Synthetase Inhibitors and Relating Specificity to Conformational Change. J. Comput. Aided Mol. Des. 20 (3) (2006)
Ming Lei, Maria I. Zavodszky, Leslie A. Kuhn, M. F. Thorpe
Sampling protein conformations and pathways. J. Comput. Chem. 25 (9) (2004)
Michael L. Raymer, Travis E. Doom, Leslie A. Kuhn, William F. Punch III
Knowledge discovery in medical and biological datasets using a hybrid Bayes classifier/evolutionary algorithm. IEEE Trans. Syst. Man Cybern. Part B 33 (5) (2003)
Maria I. Zavodszky, Paul C. Sanschagrin, Rajesh S. Korde, Leslie A. Kuhn
Distilling the essential features of a protein surface for improving protein-ligand docking, scoring, and virtual screening. J. Comput. Aided Mol. Des. 16 (12) (2002)
Elizabeth E. Howell, Ushma Shukla, Stephanie N. Hicks, R. Derike Smiley, Leslie A. Kuhn, Maria I. Zavodszky
One site fits both: A model for the ternary complex of folate + NADPH in R67 dihydrofolate reductase, a D2 symmetric enzyme. J. Comput. Aided Mol. Des. 15 (11) (2001)
Michael L. Raymer, Leslie A. Kuhn, William F. Punch III
Knowledge Discovery in Biological Databasets Using a Hybrid Bayes Classifier/Evolutionary Algorithm. BIBE (2001)
Michael L. Raymer, William F. Punch III, Erik D. Goodman, Leslie A. Kuhn, Anil K. Jain
Dimensionality reduction using genetic algorithms. IEEE Trans. Evol. Comput. 4 (2) (2000)
Volker Schnecke, Leslie A. Kuhn
Database Screening for HIV Protease Ligands: The Influence of Binding-Site Conformation and Representation on Ligand Selectivity. ISMB (1999)
Michael L. Raymer, William F. Punch III, Erik D. Goodman, Paul C. Sanschagrin, Leslie A. Kuhn
Simultanous Feature Extraction and Selection Using a Genetic Algorithm. ICGA (1997)