Lei Chen

Publication Activity (10 Years)

Years Active: 2007-2024
Publications (10 Years): 22

Top Topics

Gene Expression

Computational Methods

Machine Learning

Subcellular Localization

Top Venues

Comput. Math. Methods Medicine

Artif. Intell. Medicine

Publications

Jingxin Ren, Qian Gao, Xianchao Zhou, Lei Chen, Wei Guo, Kaiyan Feng, Tao Huang, Yu-Dong Cai
Identification of key gene expression associated with quality of life after recovery from COVID-19. Medical Biol. Eng. Comput. 62 (4) (2024)
Yueyang Li, Weiming Zeng, Wenhao Dong, Di Han, Lei Chen, Hongyu Chen, Hongjie Yan, Wai Ting Siok, Nizhuan Wang
A Tale of Single-channel Electroencephalogram: Devices, Datasets, Signal Processing, Applications, and Future Directions. CoRR (2024)
Rongguang Ye, Lei Chen, Weiduo Liao, Jinyuan Zhang, Hisao Ishibuchi
Data-Driven Preference Sampling for Pareto Front Learning. CoRR (2024)
Lei Chen, Jing Xu, Yubin Zhou
PDATC-NCPMKL: Predicting drug's Anatomical Therapeutic Chemical (ATC) codes based on network consistency projection and multiple kernel learning. Comput. Biol. Medicine 169 (2024)
Jingxin Ren, Xianchao Zhou, Ke Huang, Lei Chen, Wei Guo, Kaiyan Feng, Tao Huang, Yu-Dong Cai
Identification of key genes associated with persistent immune changes and secondary immune activation responses induced by influenza vaccination after COVID-19 recovery by machine learning methods. Comput. Biol. Medicine 169 (2024)
Lei Chen, Jiahui Gu, Bo Zhou
PMiSLocMF: predicting miRNA subcellular localizations by incorporating multi-source features of miRNAs. Briefings Bioinform. 25 (5) (2024)
Lei Chen, Yuwei Chen
RMTLysPTM: recognizing multiple types of lysine PTM sites by deep analysis on sequences. Briefings Bioinform. 25 (1) (2023)
Xiaoyong Pan, Lei Chen, Min Liu, Zhibin Niu, Tao Huang, Yu-Dong Cai
Identifying Protein Subcellular Locations With Embeddings-Based node2loc. IEEE ACM Trans. Comput. Biol. Bioinform. 19 (2) (2022)
Yuanyuan Zhu, Bin Hu, Lei Chen, Qi Dai
iMPTCE-Hnetwork: A Multilabel Classifier for Identifying Metabolic Pathway Types of Chemicals and Enzymes with a Heterogeneous Network. Comput. Math. Methods Medicine 2021 (2021)
Yanjuan Jia, Ran Zhao, Lei Chen
Similarity-Based Machine Learning Model for Predicting the Metabolic Pathways of Compounds. IEEE Access 8 (2020)
Jian-Peng Zhou, Lei Chen, Zi-Han Guo
iATC-NRAKEL: an efficient multi-label classifier for recognizing anatomical therapeutic chemical classes of drugs. Bioinform. 36 (5) (2020)
Haiyan Liang, Lei Chen, Xian Zhao, Xiaolin Zhang
Prediction of Drug Side Effects with a Refined Negative Sample Selection Strategy. Comput. Math. Methods Medicine 2020 (2020)
Jian-Peng Zhou, Lei Chen, Tianyun Wang, Min Liu
iATC-FRAKEL: a simple multi-label web server for recognizing anatomical therapeutic chemical classes of drugs with their fingerprints only. Bioinform. 36 (11) (2020)
Ran Zhao, Lei Chen, Bo Zhou, Zi-Han Guo, Shuaiqun Wang, Aorigele
Recognizing Novel Tumor Suppressor Genes Using a Network Machine Learning Strategy. IEEE Access 7 (2019)
Xiaolin Zhang, Lei Chen, Zi-Han Guo, Haiyan Liang
Identification of Human Membrane Protein Types by Incorporating Network Embedding Methods. IEEE Access 7 (2019)
Lei Chen, Xiaoyong Pan, Tao Zeng, Yu-Hang Zhang, Tao Huang, Yu-Dong Cai
Identifying Essential Signature Genes and Expression Rules Associated With Distinctive Development Stages of Early Embryonic Cells. IEEE Access 7 (2019)
Quan Zou, Lei Chen, Tao Huang, Zhenguo Zhang, Yungang Xu
Machine learning and graph analytics in computational biomedicine. Artif. Intell. Medicine 83 (2017)
Lei Chen, Yu-Hang Zhang, Guohui Lu, Tao Huang, Yu-Dong Cai
Analysis of cancer-related lncRNAs using gene ontology and KEGG pathways. Artif. Intell. Medicine 76 (2017)
Lei Chen, Shaopeng Wang, Yu-Hang Zhang, Jiarui Li, Zhi-Hao Xing, Jialiang Yang, Tao Huang, Yu-Dong Cai
Identify Key Sequence Features to Improve CRISPR sgRNA Efficacy. IEEE Access 5 (2017)
Chao Wang, Lei Chen, Changhong Lu
k-Power domination in block graphs. J. Comb. Optim. 31 (2) (2016)
Jian Zhang, Jing Yang, Tao Huang, Yang Shu, Lei Chen
Identification of novel proliferative diabetic retinopathy related genes on protein-protein interaction network. Neurocomputing 217 (2016)
Nizhuan Wang, Weiming Zeng, Dongtailang Chen, Jun Yin, Lei Chen
A Novel Brain Networks Enhancement Model (BNEM) for BOLD fMRI Data Analysis With Highly Spatial Reproducibility. IEEE J. Biomed. Health Informatics 20 (4) (2016)
Lei Chen, Tao Huang, Chuan Lu, Lin Lu, Dandan Li
Machine Learning and Network Methods for Biology and Medicine. Comput. Math. Methods Medicine 2015 (2015)
Lei Chen, Changhong Lu, Zhenbing Zeng
Graphs with unique minimum paired-dominating set. Ars Comb. 119 (2015)
Yudong Cai, Tao Huang, Lei Chen, Shan Gao, Ning Zhang
Novel Computational Methods and Tools in Biomedicine and Biopharmacy. Comput. Math. Methods Medicine 2014 (2014)
Lei Chen, Weiming Zeng, Changhong Lu
NP-completeness and APX-completeness of restrained domination in graphs. Theor. Comput. Sci. 448 (2012)
Lei Chen, Changhong Lu, Zhenbing Zeng
Vertices in all minimum paired-dominating sets of block graphs. J. Comb. Optim. 24 (3) (2012)
Tao Huang, Lei Chen, Xiao-Jun Liu, Yu-Dong Cai
Predicting triplet of transcription factor - mediating enzyme - target gene by functional profiles. Neurocomputing 74 (17) (2011)
Lei Chen, Ziliang Qian, Kaiyan Feng, Yudong Cai
Prediction of interactiveness between small molecules and enzymes by combining gene ontology and compound similarity. J. Comput. Chem. 31 (8) (2010)
Lei Chen, Changhong Lu, Zhenbing Zeng
Labelling algorithms for paired-domination problems in block and interval graphs. J. Comb. Optim. 19 (4) (2010)
Lei Chen, Kai-Yan Feng, Yu-Dong Cai, Kuo-Chen Chou, Hai-Peng Li
Predicting the network of substrate-enzyme-product triads by combining compound similarity and functional domain composition. BMC Bioinform. 11 (2010)
Lei Chen, Lin Lu, Kairui Feng, Wenjin Li, Jie Song, Lulu Zheng, Youlang Yuan, Zhenbing Zeng, Kai-Yan Feng, Wen-Cong Lu, Yudong Cai
Multiple classifier integration for the prediction of protein structural classes. J. Comput. Chem. 30 (14) (2009)
Lei Chen, Changhong Lu, Zhenbing Zeng
A linear-time algorithm for paired-domination problem in strongly chordal graphs. Inf. Process. Lett. 110 (1) (2009)
Lei Chen, Changhong Lu, Zhenbing Zeng
Hardness results and approximation algorithms for (weighted) paired-domination in graphs. Theor. Comput. Sci. 410 (47-49) (2009)
Lei Chen, Changhong Lu, Zhenbing Zeng
Distance paired-domination problems on subclasses of chordal graphs. Theor. Comput. Sci. 410 (47-49) (2009)
Changhong Lu, Lei Chen, Mingqing Zhai
Extremal problems on consecutive L(2, 1)-labelling. Discret. Appl. Math. 155 (10) (2007)