Hirokazu Sugiyama

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 18

Top Topics

Mass Customization

Manufacturing Process

Top Venues

Comput. Chem. Eng.

Publications

Kozue Okamura, Kota Oishi, Sara Badr, Akira Yamada, Hirokazu Sugiyama
Data-driven parameterization and development of mechanistic cell cultivation models in monoclonal antibody production processes: Shifts in cell metabolic behavior. Comput. Chem. Eng. 191 (2024)
Benedikt X. Scholz, Yusuke Hayashi, Isuru A. Udugama, Masahiro Kino-oka, Hirokazu Sugiyama
A CFD model-based design of seeding processes for two-dimensional mesenchymal stem cell cultivation. Comput. Chem. Eng. 171 (2023)
Isuru A. Udugama, Sara Badr, Keita Hirono, Benedikt X. Scholz, Yusuke Hayashi, Masahiro Kino-oka, Hirokazu Sugiyama
The role of process systems engineering in applying quality by design (QbD) in mesenchymal stem cell production. Comput. Chem. Eng. 172 (2023)
Kensaku Matsunami, Tomohiro Miura, Keita Yaginuma, Shuichi Tanabe, Sara Badr, Hirokazu Sugiyama
Surrogate modeling of dissolution behavior toward efficient design of tablet manufacturing processes. Comput. Chem. Eng. 171 (2023)
Daniel R. Lewin, Emilia M. Kondili, Ian T. Cameron, Grégoire Léonard, Seyed Soheil Mansouri, Fernando Gomes Martins, Luis A. Ricardez-Sandoval, Hirokazu Sugiyama, Edwin Zondervan
Agile process systems engineering education: What to teach, and how to teach. Comput. Chem. Eng. 170 (2023)
Junu Kim, Hironori Yonekura, Takeaki Watanabe, Satoshi Yoshikawa, Hayao Nakanishi, Sara Badr, Hirokazu Sugiyama
Model-based comparison of batch and flow syntheses of an active pharmaceutical ingredient using heterogeneous hydrogenation. Comput. Chem. Eng. 156 (2022)
Benedikt X. Scholz, Yusuke Hayashi, Isuru A. Udugama, Masahiro Kino-oka, Hirokazu Sugiyama
A multilayered approach to scale-up forced convection-based freezing of human induced pluripotent stem cells. Comput. Chem. Eng. 163 (2022)
Yusuke Hayashi, Masahiro Kino-oka, Hirokazu Sugiyama
Hybrid-model-based design of fill-freeze-thaw processes for human induced pluripotent stem cells considering productivity and quality. Comput. Chem. Eng. 156 (2022)
Sara Badr, Kozue Okamura, Nozomi Takahashi, Vera Ubbenjans, Haruku Shirahata, Hirokazu Sugiyama
Integrated design of biopharmaceutical manufacturing processes: Operation modes and process configurations for monoclonal antibody production. Comput. Chem. Eng. 153 (2021)
Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
Model-based assessment of temperature profiles in slow freezing for human induced pluripotent stem cells. Comput. Chem. Eng. 144 (2021)
Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
Slow freezing process design for human induced pluripotent stem cells by modeling intracontainer variation. Comput. Chem. Eng. 132 (2020)
Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
Data mining algorithm for pre-processing biopharmaceutical drug product manufacturing records. Comput. Chem. Eng. 124 (2019)
Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
Multiobjective decision-support tools for the choice between single-use and multi-use technologies in sterile filling of biopharmaceuticals. Comput. Chem. Eng. 122 (2019)
Koki Tsushima, Kazuki Uchida, Xu Han, Hirokazu Sugiyama, Masaki Aikawa, Natsuki Hayasaka, Masaki Matsuura, Takahiro Ishizaki, Takuto Shirai, Kazuhiko Shimomura
Lasing Characteristics of GalnAsP SCH MQW High-mesa Laser on Silicon Substrate. OECC/PSC (2019)
Takahiro Ishizaki, Kazuki Uchida, Hirokazu Sugiyama, Xu Han, Natsuki Hayasaka, Masaki Aikawa, Masaki Matsuura, Koki Tsushima, Takuto Shirai, Kazuhiko Shimomura
Lasing characteristics of GalnAsP SCH-MQW Laser Diode on Directly-bonded InP/Si Substrate. OECC/PSC (2019)
Haruku Shirahata, Sara Badr, Shant Dakessian, Hirokazu Sugiyama
Alternative generation and multiobjective evaluation using a design framework: Case study on sterile filling processes of biopharmaceuticals. Comput. Chem. Eng. 123 (2019)
Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbühler
Data-driven tiered procedure for enhancing yield in drug product manufacturing. Comput. Chem. Eng. 87 (2016)
Lukas Gallus Eberle, Elisabet Capón-García, Hirokazu Sugiyama, Andreas Graser, Rainer Schmidt, Konrad Hungerbühler
Rigorous approach to scheduling of sterile drug product manufacturing. Comput. Chem. Eng. 94 (2016)
Gioele Casola, Satoshi Yoshikawa, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama
Systematic retrofitting methodology for pharmaceutical drug purification processes. Comput. Chem. Eng. 80 (2015)
Lukas Gallus Eberle, Hirokazu Sugiyama, Rainer Schmidt
Improving lead time of pharmaceutical production processes using Monte Carlo simulation. Comput. Chem. Eng. 68 (2014)