Glen E. P. Ropella

Publication Activity (10 Years)

Years Active: 2004-2020
Publications (10 Years): 5

Top Topics

Knowledge Communities

Computational Models

Top Venues

SpringSim (ADS)

PLoS Comput. Biol.

BMC Syst. Biol.

Int. J. Agent Technol. Syst.

Publications

Andrew K. Smith, Glen E. P. Ropella, Mitchell R. McGill, Preethi Krishnan, Lopamudra Dutta, Ryan C. Kennedy, Hartmut Jaeschke, C. Anthony Hunt
Contrasting model mechanisms of alanine aminotransferase (ALT) release from damaged and necrotic hepatocytes as an example of general biomarker mechanisms. PLoS Comput. Biol. 16 (6) (2020)
Andrew K. Smith, Glen E. P. Ropella, C. Anthony Hunt, Neil Kaplowitz, Murad Ookhtens
Virtual experiments help explain intra- and inter-strain variability of AILI-induced hepatic necrosis in mice. SpringSim (ADS) (2016)
Andrew K. Smith, Brenden K. Petersen, Glen E. P. Ropella, Ryan C. Kennedy, Neil Kaplowitz, Murad Ookhtens, C. Anthony Hunt
Competing Mechanistic Hypotheses of Acetaminophen-Induced Hepatotoxicity Challenged by Virtual Experiments. PLoS Comput. Biol. 12 (12) (2016)
Glen E. P. Ropella, C. Anthony Hunt
Measuring analog granularity. SpringSim (ADS) (2016)
Ryan C. Kennedy, Glen E. P. Ropella, C. Anthony Hunt
Implementing a cell-centered, agent-based framework with flexible environment granularities using MASON and VTK. SpringSim (ADS) (2016)
Brenden K. Petersen, Glen E. P. Ropella, C. Anthony Hunt
Toward modular biological models: defining analog modules based on referent physiological mechanisms. BMC Syst. Biol. 8 (2014)
Andrew K. Smith, Glen E. P. Ropella, Neil Kaplowitz, Murad Ookhtens, C. Anthony Hunt
Mechanistic agent-based damage and repair models as hypotheses for patterns of necrosis caused by drug induced liver injury. SummerSim (2014)
Glen E. P. Ropella, C. Anthony Hunt
Zonation of drug-induced, hepatic enzyme induction: falsifying fine grained mechanisms within a validated, multiscale In Silico Liver. SpringSim (ADS) (2012)
Glen E. P. Ropella, Ryan C. Kennedy, C. Anthony Hunt
Falsifying an Enzyme Induction Mechanism within a Validated, Multiscale Liver Model. Int. J. Agent Technol. Syst. 4 (3) (2012)
Glen E. P. Ropella, C. Anthony Hunt
Cloud computing and validation of expandable in silico livers. BMC Syst. Biol. 4 (2010)
Sean H. J. Kim, Sunwoo Park, Glen E. P. Ropella, C. Anthony Hunt
Agent-Directed Tracing of Multi-Scale Drug Disposition Events within Normal and Diseased In Silico Livers. Int. J. Agent Technol. Syst. 2 (3) (2010)
Sean H. J. Kim, Sunwoo Park, Glen E. P. Ropella, C. Anthony Hunt
Agent-based simulation of drug disposition in cirrhotic liver. SpringSim (2010)
Glen E. P. Ropella, Sunwoo Park, C. Anthony Hunt
Evaluating an hepatic enzyme induction mechanism through coarse- and fine-grained measurements of an in silico liver. Complex. 14 (6) (2009)
Tai Ning Lam, Glen E. P. Ropella, C. Anthony Hunt
Focus on discovering mechanisms: a relativistic, agent-directed, perfused liver. SpringSim (2009)
Li Yan, Sunwoo Park, Shahab Sheikh-Bahaei, Glen E. P. Ropella, C. Anthony Hunt
Predicting hepatic disposition properties of cationic drugs using a physiologically based, agent-oriented In Silico Liver. SpringSim (2008)
Jesse Engelberg, Glen E. P. Ropella, C. Anthony Hunt
Essential operating principles for tumor spheroid growth. BMC Syst. Biol. 2 (2008)
Jesse Engelberg, Glen E. P. Ropella, C. Anthony Hunt
Affects of Surface Detection on Shape and Growth of Model Tumor Spheroids. CAINE (2007)
Sunwoo Park, Sean H. J. Kim, Glen E. P. Ropella, C. Anthony Hunt
Tracking Compounds and Their Interactions within In Silico Liver. CAINE (2007)
C. Anthony Hunt, Glen E. P. Ropella, Michael S. Roberts, Li Yan
Biomimetic in Silico Devices. CMSB (2004)