Research and applications: Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases.
Younghee LeeHaiquan LiJianrong LiEllen RebmanIkbel AchourKelly ReganEric R. GamazonJames L. ChenXinan Holly YangNancy J. CoxYves A. LussierPublished in: J. Am. Medical Informatics Assoc. (2013)
Keyphrases
- complex diseases
- protein interaction
- biological data
- network structure
- gene gene interactions
- statistical models
- gene expression
- genome wide association studies
- feature selection
- model selection
- statistical model
- databases
- high speed
- data sources
- biological systems
- protein protein interactions
- wireless sensor networks
- decision trees