Uncover cooperative gene regulations by microRNAs and transcription factors in glioblastoma using a nonnegative hybrid factor model.
Jia MengHung-I Harry ChenJianqiu ZhangYidong ChenYufei HuangPublished in: ICASSP (2011)
Keyphrases
- gene regulation
- transcription factors
- binding sites
- gene expression
- microarray
- gene expression data
- regulatory networks
- dna binding
- transcription factor binding sites
- cis regulatory
- high throughput
- systems biology
- gene regulatory networks
- genome wide
- dna sequences
- biological processes
- saccharomyces cerevisiae
- post transcriptional
- biological systems
- cell cycle
- component analysis
- motif discovery
- transcriptional regulation
- biomedical literature
- sequence data
- co occurrence
- computational biology
- protein interaction
- gene ontology
- genomic sequences
- differentially expressed genes
- microarray data
- gene sets
- signaling pathways
- biological networks
- gene selection
- gene expression profiles
- computational methods
- magnetic resonance imaging