Disease-Aging Network Reveals Significant Roles of Aging Genes in Connecting Genetic Diseases.
Jiguang WangShi-Hua ZhangYong WangLuonan ChenXiang-Sun ZhangPublished in: PLoS Comput. Biol. (2009)
Keyphrases
- complex diseases
- software aging
- gene gene interactions
- age related
- single nucleotide polymorphisms
- genome wide association studies
- association studies
- gene gene
- genetic regulatory networks
- drosophila melanogaster
- age estimation
- gene networks
- disease diagnosis
- gene expression
- genome wide
- microarray
- protein protein interaction networks
- disease genes
- differentially expressed genes
- haplotype inference
- genetic variation
- candidate genes
- early diagnosis
- diagnostic process
- interaction networks
- network model
- gene interactions
- biological entities
- severe acute respiratory syndrome
- human genome
- related genes
- biological knowledge
- highly correlated
- high throughput
- gene expression data
- genomic data
- clinically relevant