ChIP-GSM: Inferring active transcription factor modules to predict functional regulatory elements.
Xi ChenAndrew F. NeuwaldLeena Hilakivi-ClarkeRobert ClarkeJianhua XuanPublished in: PLoS Comput. Biol. (2021)
Keyphrases
- regulatory elements
- transcription factors
- binding sites
- dna sequences
- sequence data
- gene expression
- microarray
- transcription factor binding sites
- component analysis
- computational biology
- genome wide
- gene regulation
- high speed
- low cost
- co occurrence
- regulatory networks
- systems biology
- highly correlated
- biomedical literature
- motif discovery
- human genome
- biological sequences
- gene expression data
- statistical analysis
- statistical tests
- microarray data
- high dimensionality
- high throughput