Exhaustive Search of the SNP-SNP Interactome Identifies Epistatic Effects on Brain Volume in Two Cohorts.
Derrek P. HibarJason L. SteinNeda JahanshadOmid KohannimArthur W. TogaKatie McMahonGreig I. de ZubicarayGrant W. MontgomeryNicholas G. MartinMargaret J. WrightMichael W. WeinerPaul M. ThompsonPublished in: MICCAI (3) (2013)
Keyphrases
- exhaustive search
- genome wide
- statistical methods
- computational complexity
- genomic data
- brute force
- dynamic programming
- computationally feasible
- single nucleotide polymorphisms
- search space
- solution space
- human genome
- search methods
- high throughput
- mri scans
- linkage disequilibrium
- human brain
- brain images
- machine learning
- special case
- lower bound
- optimal solution