Clustering disease trajectories in contrastive feature space for biomarker discovery in age-related macular degeneration.
Robbie HollandOliver LeingangChristopher HolmesPhilipp AndersJohannes C. PaetzoldRebecca KayeSophie RiedlHrvoje BogunovicUrsula Schmidt-ErfurthLars FritscheHendrik P. N. SchollSobha SivaprasadAndrew J. LoteryDaniel RueckertMartin J. MentenPublished in: CoRR (2023)
Keyphrases
- feature space
- biomarker discovery
- age related macular degeneration
- data points
- mass spectrometry data
- high dimensionality
- high dimensional
- classification accuracy
- clustering method
- clustering algorithm
- cluster analysis
- k means
- feature vectors
- dimensionality reduction
- training set
- high throughput
- feature selection
- data sets
- feature extraction
- rule learning
- decision trees