Erosion of Conserved Binding Sites in Personal Genomes Points to Medical Histories.
Harendra GuturuSandeep ChinchaliShoa L. ClarkeGill BejeranoPublished in: PLoS Comput. Biol. (2016)
Keyphrases
- binding sites
- sequence data
- regulatory elements
- sequence alignment
- sequenced genomes
- protein families
- dna sequences
- gene expression
- transcription factor binding sites
- coding regions
- transcription factors
- dna binding
- protein coding regions
- motif discovery
- phylogenetic analysis
- genome sequences
- biological sequences
- sequence analysis
- human genome
- comparative analysis
- genomic sequences
- statistical significance
- comparative genomics
- microarray
- genomic data
- machine learning
- statistical analysis
- high dimensional