What Population Reveals about Individual Cell Identity: Single-Cell Parameter Estimation of Models of Gene Expression in Yeast.
Artémis LlamosiAndrés M. González-VargasCristian VersariEugenio CinquemaniGiancarlo Ferrari-TrecatePascal HersenGrégory BattPublished in: PLoS Comput. Biol. (2016)
Keyphrases
- parameter estimation
- gene expression
- gene expression data
- microarray
- statistical models
- maximum likelihood
- model selection
- least squares
- em algorithm
- regulatory networks
- markov random field
- high throughput
- binding sites
- biological networks
- transcription factors
- cell cycle
- microarray data
- biological processes
- gene regulation
- expectation maximization
- signaling pathways
- dna binding
- parameter estimation algorithm
- gene regulatory networks
- approximate inference
- gene expression profiles
- parameter estimates
- probabilistic model
- protein interaction
- structure learning
- biological data
- high dimensionality
- saccharomyces cerevisiae
- higher order