SBSI: an extensible distributed software infrastructure for parameter estimation in systems biology.
Richard R. AdamsAllan ClarkAzusa YamaguchiNeil HanlonNikos TsormanShakir AliGalina LebedevaAlexey GoltsovAnatoly A. SorokinOzgur E. AkmanCarl TroeinAndrew J. MillarIgor GoryaninStephen GilmorePublished in: Bioinform. (2013)
Keyphrases
- parameter estimation
- systems biology
- high throughput
- maximum likelihood
- least squares
- biological systems
- biological data
- markov random field
- model selection
- statistical models
- em algorithm
- parameter estimation algorithm
- structure learning
- biological networks
- molecular biology
- gene regulatory networks
- expectation maximization
- computational biology
- maximum likelihood estimation
- approximate inference
- microarray
- prior information
- protein protein interactions
- feature selection
- data analysis