AREM: Aligning Short Reads from ChIP-Sequencing by Expectation Maximization.
Daniel NewkirkJacob BiesingerAlvin ChonKyoko YokomoriXiaohui XiePublished in: RECOMB (2011)
Keyphrases
- expectation maximization
- em algorithm
- mixture model
- probabilistic model
- high speed
- maximum likelihood
- generative model
- low cost
- gaussian mixture model
- reference genome
- analog vlsi
- parameter estimation
- bayesian framework
- programmable logic
- probability density function
- gaussian mixture
- vlsi design
- high density
- mixture of gaussians
- vlsi implementation
- real time
- image registration
- maximum likelihood estimation
- density estimation
- signal processing
- chip design
- functional verification
- high throughput sequencing
- unsupervised learning