Boosting power to detect genetic associations in imaging using multi-locus, genome-wide scans and ridge regression.
Omid KohannimDerrek P. HibarJason L. SteinNeda JahanshadClifford R. JackMichael WeinerArthur W. TogaPaul M. ThompsonPublished in: ISBI (2011)
Keyphrases
- genome wide
- ridge regression
- genome wide association studies
- human genome
- high throughput
- gene gene interactions
- genetic variation
- complex diseases
- linkage disequilibrium
- linear regression
- single nucleotide polymorphisms
- regression methods
- association studies
- support vector machine
- ls svm
- ensemble methods
- data acquisition
- genetic algorithm
- microarray
- biological data
- support vector
- feature selection
- learning algorithm
- data mining
- statistically significant
- image classification
- pairwise
- decision trees