Determining Effects of Non-synonymous SNPs on Protein-Protein Interactions using Supervised and Semi-supervised Learning.
Nan ZhaoJing Ginger HanChi-Ren ShyuDmitry KorkinPublished in: PLoS Comput. Biol. (2014)
Keyphrases
- protein protein interactions
- genomic data
- supervised and semi supervised learning
- high throughput
- computational methods
- predicting protein protein interactions
- biological processes
- genome wide
- network topology
- gene ontology
- biological data
- biomedical literature
- protein interaction
- high precision
- computational approaches
- systems biology
- functional modules
- biological networks
- wet lab
- structural properties
- network analysis
- protein interaction networks
- protein complexes
- protein protein
- machine learning
- single nucleotide polymorphisms
- data mining
- biological systems