Constrained Maximum Likelihood Estimation of Relative Abundances of Protein Conformation in a Heterogeneous Mixture From Small Angle X-Ray Scattering Intensity Measurements.
A. Emre OnukMurat AkçakayaJaydeep P. BardhanDeniz ErdogmusDana H. BrooksLee MakowskiPublished in: IEEE Trans. Signal Process. (2015)
Keyphrases
- x ray
- maximum likelihood estimation
- multivariate gaussian
- expectation maximization
- mixture of gaussians
- protein structure
- em algorithm
- maximum likelihood
- protein folding
- protein structure prediction
- x ray images
- medical imaging
- dead end
- probability distribution
- intraoperative
- mixture model
- electron microscope
- digital x ray images
- amino acids
- sequence analysis
- tomographic images
- parameter estimation
- protein sequences
- electron microscopy
- three dimensional
- density function
- gaussian distribution
- projection images
- image intensity
- image processing
- gaussian mixture model
- guide wire
- least squares
- probabilistic model
- metal oxide