Experimental design trade-offs for gene regulatory network inference: An in silico study of the yeast Saccharomyces cerevisiae cell cycle.
Johan MarkdahlNicolò ColomboJohan ThunbergJorge M. GoncalvesPublished in: CDC (2017)
Keyphrases
- saccharomyces cerevisiae
- gene regulatory networks
- cell cycle
- biological data
- budding yeast
- regulatory networks
- gene expression data
- microarray data
- protein protein interactions
- protein protein interaction networks
- systems biology
- biological processes
- reverse engineering
- bayesian inference
- dynamic bayesian networks
- network model
- gene regulation
- high throughput
- experimental conditions
- gene networks
- microarray
- interaction networks
- structure learning
- biological networks
- protein function
- data sets
- gene expression
- molecular biology
- statistical methods
- high precision
- data sources
- active learning
- feature selection