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Mechanistic analysis of multi-omics datasets to generate kinetic parameters for constraint-based metabolic models.
Cameron Cotten
Jennifer L. Reed
Published in:
BMC Bioinform. (2013)
Keyphrases
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parameter estimation
mathematical modeling
statistical models
model validation
high dimensional
free parameters
parametric models
experimental data
complex systems
analytical models
sensitivity analysis
database
model selection
maximum likelihood
graphical models
least squares
probabilistic model
genetic algorithm