Identifying individual risk rare variants using protein structure guided local tests (POINT).
Rachel Marceau WestWenbin LuDaniel M. RotroffMélaine A. KuenemannSheng-Mao ChangMichael C. WuMichael J. WagnerJohn B. BuseAlison A. Motsinger-ReifDenis FourchesJung-Ying TzengPublished in: PLoS Comput. Biol. (2019)
Keyphrases
- protein structure
- protein sequences
- molecular biology
- secondary structure
- amino acid sequences
- protein structure prediction
- protein structure and function
- protein tertiary structure
- protein function
- amino acids
- protein structure alignment
- protein structural
- high quality
- computational approaches
- nuclear magnetic resonance
- computational biology
- statistical tests
- fine grained
- lower bound