Prediction of protein-protein interactions by combining structure and sequence conservation in protein interfaces.
A. Selim AytunaAttila GürsoyOzlem KeskinPublished in: Bioinform. (2005)
Keyphrases
- protein protein interactions
- multiple sequence alignments
- protein interaction
- predicting protein
- drug design
- computational methods
- wet lab
- interacting proteins
- protein interaction data
- structural properties
- sequence similarity
- contact map
- high throughput
- protein protein
- predicting protein protein interactions
- protein sequences
- functional modules
- protein function
- protein function prediction
- biological processes
- biological data
- protein complexes
- gene ontology
- biomedical literature
- computational approaches
- biological networks
- cellular processes
- experimentally determined
- protein interaction networks
- high precision
- protein structure prediction
- network topology
- genomic data
- sequence analysis
- systems biology
- multiple sequence alignment
- network analysis
- ad hoc networks
- protein protein interaction networks
- protein structure