Scalable nonlinear programming framework for parameter estimation in dynamic biological system models.
Sungho ShinOphelia VenturelliVictor M. ZavalaPublished in: PLoS Comput. Biol. (2019)
Keyphrases
- parameter estimation
- statistical models
- model selection
- model fitting
- maximum likelihood
- random fields
- nonlinear programming
- em algorithm
- least squares
- markov random field
- probabilistic model
- linear programming
- expectation maximization
- estimation problems
- parameter estimation algorithm
- bayesian framework
- generative model
- parametric models
- pairwise
- parameter estimates
- stochastic logic programs