UbiSite: incorporating two-layered machine learning method with substrate motifs to predict ubiquitin-conjugation site on lysines.
Chien-Hsun HuangMin-Gang SuHui-Ju KaoJhih-Hua JhongShun-Long WengTzong-Yi LeePublished in: BMC Syst. Biol. (2016)
Keyphrases
- machine learning
- detection method
- preprocessing
- clustering method
- experimental evaluation
- support vector machine
- machine learning methods
- objective function
- synthetic data
- significant improvement
- cost function
- protein secondary structure prediction
- high precision
- unsupervised learning
- high accuracy
- computational cost
- denoising
- feature set
- dynamic programming
- data analysis
- computational complexity
- face recognition
- decision trees
- data sets