Prediction and ranking of human protein-protein interactions within a Bayesian framework.
Michelle S. ScottGeoffrey J. BartonPublished in: BMC Syst. Biol. (2007)
Keyphrases
- bayesian framework
- protein interaction
- protein protein interactions
- prior knowledge
- computational methods
- wet lab
- drug design
- generative model
- high throughput
- network topology
- biomedical literature
- expectation maximization
- gene ontology
- predicting protein protein interactions
- protein function
- protein interaction networks
- biological data
- gaussian process
- protein function prediction
- structural properties
- maximum a posteriori
- protein complexes
- gene expression
- network analysis
- high precision
- computational approaches
- probabilistic model
- biological systems
- binding sites
- maximum likelihood
- data sets