Sequence-structure specificity of a knowledge based energy function at the secondary structure level.
Dong XuMichael A. UnserenYing XuEdward C. UberbacherPublished in: Bioinform. (2000)
Keyphrases
- energy function
- secondary structure
- secondary structure of proteins
- tertiary structure
- sequence similarity
- energy minimization
- graph cuts
- protein secondary structure prediction
- protein sequences
- markov random field
- structural features
- computational methods
- predicting protein
- protein structure
- global minimum
- neural network
- image segmentation
- rna sequences
- hopfield neural network
- energy landscape
- rna secondary structures
- level set
- splice site
- active contours
- amino acids
- protein folding
- amino acid sequences
- rna molecules
- protein secondary structure
- psi blast
- multiple sequence alignment
- maximum a posteriori
- belief propagation
- genetic algorithm
- rna secondary structure prediction
- image processing
- bayesian networks
- ordering constraints
- hidden markov models
- shape prior