Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach.
Dirk RepsilberSabine KernAnna TelaarGerhard WalzlGillian F. BlackJoachim SelbigShreemanta K. ParidaStefan H. E. KaufmannMarc JacobsenPublished in: BMC Bioinform. (2010)
Keyphrases
- tissue samples
- biomarker discovery
- mass spectrometry data
- microarray
- high throughput
- gene expression data
- biological data
- cancer diagnosis
- cancer classification
- cell nuclei
- gene regulatory networks
- microarray data
- image processing
- rule learning
- gene expression profiles
- low contrast
- systems biology
- gene selection
- random forest
- pattern classification
- input data