Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models.
Florian MartinAlain SewerMarja TalikkaYang XiangJulia HoengManuel C. PeitschPublished in: BMC Bioinform. (2014)
Keyphrases
- causal models
- biological networks
- connected subgraphs
- directed acyclic graph
- biological data
- causal discovery
- protein protein interaction networks
- conditional independence
- biological systems
- gene expression
- structural equation models
- causal reasoning
- causal relationships
- graph mining
- complex networks
- link prediction
- interaction networks
- tractable cases
- causal structure
- community detection
- pattern mining
- community structure
- data sets
- gene regulatory networks
- network analysis
- computational model
- data integration
- data mining
- high throughput
- protein protein interactions