Using NMR Chemical Shifts and Cryo-EM Density Restraints in Iterative Rosetta-MD Protein Structure Refinement.
Sumudu P. LeelanandaSteffen LindertPublished in: J. Chem. Inf. Model. (2020)
Keyphrases
- protein structure
- contact map
- nuclear magnetic resonance
- molecular biology
- protein sequences
- expectation maximization
- em algorithm
- secondary structure
- protein structure prediction
- chemical compounds
- amino acid sequences
- probabilistic model
- protein tertiary structure
- electron microscopy
- maximum likelihood
- amino acids
- protein structure alignment
- protein backbone
- sequence alignment
- fine grained
- protein structural
- machine learning