Steffen Lindert

Publication Activity (10 Years)

Years Active: 2012-2024
Publications (10 Years): 13

Top Topics

Protein Backbone

Coronary Artery

Top Venues

J. Chem. Inf. Model.

Briefings Bioinform.

J. Comput. Aided Mol. Des.

Publications

William T. Higgins, Sandip Vibhute, Chad Bennett, Steffen Lindert
Discovery of Nanomolar Inhibitors for Human Dihydroorotate Dehydrogenase Using Structure-Based Drug Discovery Methods. J. Chem. Inf. Model. 64 (2) (2024)
Eric R. Hantz, Svetlana B. Tikunova, Natalya Belevych, Jonathan P. Davis, Peter J. Reiser, Steffen Lindert
Targeting Troponin C with Small Molecules Containing Diphenyl Moieties: Calcium Sensitivity Effects on Striated Muscles and Structure-Activity Relationship. J. Chem. Inf. Model. 63 (11) (2023)
S. M. Bargeen Alam Turzo, Justin T. Seffernick, Sergey Lyskov, Steffen Lindert
Predicting ion mobility collision cross sections using projection approximation with ROSIE-PARCS webserver. Briefings Bioinform. 24 (5) (2023)
Austin M. Cool, Steffen Lindert
Umbrella Sampling Simulations of Cardiac Thin Filament Reveal Thermodynamic Consequences of Troponin I Inhibitory Peptide Mutations. J. Chem. Inf. Model. 63 (11) (2023)
Eric R. Hantz, Steffen Lindert
Actives-Based Receptor Selection Strongly Increases the Success Rate in Structure-Based Drug Design and Leads to Identification of 22 Potent Cancer Inhibitors. J. Chem. Inf. Model. 62 (22) (2022)
Eric R. Hantz, Steffen Lindert
Computational Exploration and Characterization of Potential Calcium Sensitizing Mutations in Cardiac Troponin C. J. Chem. Inf. Model. 62 (23) (2022)
Austin M. Cool, Steffen Lindert
Umbrella Sampling Simulations Measure Switch Peptide Binding and Hydrophobic Patch Opening Free Energies in Cardiac Troponin. J. Chem. Inf. Model. 62 (22) (2022)
Eric R. Hantz, Steffen Lindert
Adaptative Steered Molecular Dynamics Study of Mutagenesis Effects on Calcium Affinity in the Regulatory Domain of Cardiac Troponin C. J. Chem. Inf. Model. 61 (6) (2021)
William H. Coldren, Svetlana B. Tikunova, Jonathan P. Davis, Steffen Lindert
Discovery of Novel Small-Molecule Calcium Sensitizers for Cardiac Troponin C: A Combined Virtual and Experimental Screening Approach. J. Chem. Inf. Model. 60 (7) (2020)
Sumudu P. Leelananda, Steffen Lindert
Using NMR Chemical Shifts and Cryo-EM Density Restraints in Iterative Rosetta-MD Protein Structure Refinement. J. Chem. Inf. Model. 60 (5) (2020)
Jacob D. Bowman, William H. Coldren, Steffen Lindert
Mechanism of Cardiac Troponin C Calcium Sensitivity Modulation by Small Molecules Illuminated by Umbrella Sampling Simulations. J. Chem. Inf. Model. 59 (6) (2019)
Melanie L. Aprahamian, Svetlana B. Tikunova, Morgan V. Price, Andres F. Cuesta, Jonathan P. Davis, Steffen Lindert
Successful Identification of Cardiac Troponin Calcium Sensitizers Using a Combination of Virtual Screening and ROC Analysis of Known Troponin C Binders. J. Chem. Inf. Model. 57 (12) (2017)
Steffen Lindert, Lorillee Tallorin, Quynh G. Nguyen, Michael D. Burkart, James Andrew McCammon
In silico screening for Plasmodium falciparum enoyl-ACP reductase inhibitors. J. Comput. Aided Mol. Des. 29 (1) (2015)
Steffen Lindert, Phoebe L. Stewart, Jens Meiler
Computational determination of the orientation of a heat repeat-like domain of DNA-PKcs. Comput. Biol. Chem. 42 (2013)
Peter Michael Kekenes-Huskey, Steffen Lindert, James Andrew McCammon
Molecular Basis of Calcium-Sensitizing and Desensitizing Mutations of the Human Cardiac Troponin C Regulatory Domain: A Multi-Scale Simulation Study. PLoS Comput. Biol. 8 (11) (2012)