Characterizing Protein Interactions Employing a Genome-Wide siRNA Cellular Phenotyping Screen.
Apichat SurataneeMartin H. SchaeferMatthew J. BettsZita SoonsHeiko A. MannspergerNathalie HarderMarcus OswaldMarkus GippEllen RammingerGuillermo Marcus MartinezReinhard MännerKarl RohrErich E. WankerRobert B. RussellMiguel A. Andrade-NavarroRoland EilsRainer KönigPublished in: PLoS Comput. Biol. (2014)
Keyphrases
- genome wide
- protein interaction
- high throughput
- protein protein interactions
- biological data
- systems biology
- microarray
- dna binding
- biological processes
- gene expression
- protein function
- computational methods
- protein interaction networks
- gene ontology
- functional modules
- genomic data
- biomedical literature
- protein complexes
- biological networks
- computational approaches
- molecular biology
- biological systems
- protein protein interaction networks
- gene gene interactions
- data acquisition
- gene expression data
- computational tools
- machine learning
- binding sites
- single nucleotide polymorphisms
- microarray data
- network topology