De-Novo Discovery of Differentially Abundant Transcription Factor Binding Sites Including Their Positional Preference.
Jens KeilwagenJan GrauIvan A. PaponovStefan PoschMarc StrickertIvo GrossePublished in: PLoS Comput. Biol. (2011)
Keyphrases
- motif discovery
- binding sites
- transcription factor binding sites
- dna sequences
- human genome
- pattern discovery
- biological sequences
- transcription factors
- data mining tasks
- gene expression
- multiobjective optimization
- computational biology
- sequence data
- dna binding
- data mining
- pattern mining
- sequential patterns
- multi objective
- biological networks
- statistical significance
- co occurrence
- knowledge discovery
- regulatory networks