Computational Strategy for Discovering Druggable Gene Networks from Genome-Wide RNA Expression Profiles.
Seiya ImotoYoshinori TamadaHiromitsu ArakiKaori YasudaCristin G. PrintStephen D. Charnock-JonesDeborah SandersChristopher J. SavoieKousuke TashiroSatoru KuharaSatoru MiyanoPublished in: Pacific Symposium on Biocomputing (2006)
Keyphrases
- genome wide
- expression profiles
- gene networks
- high throughput
- microarray
- systems biology
- microarray data
- gene expression
- gene expression data
- biological data
- human genome
- transcription factors
- gene ontology
- gene expression profiles
- experimental conditions
- protein protein interactions
- molecular biology
- gene selection
- gene regulatory networks
- regulatory networks
- low cost
- clustering analysis
- high dimensionality